On July 4, 1973, Barbados, Trinidad and Tobago, Guyana, and Jamaica signed a treaty in Trinidad to found the Caribbean Community and Common Market (CARICOM). In May 1974, most of the remaining English-speaking Caribbean states joined CARICOM, which now has 14 members. Barbados also is a member of the Caribbean Development Bank, established in 1970, with headquarters in Bridgetown. The eastern Caribbean's Regional Security System, which associates Barbados with six other island nations, also is headquartered in Barbados. In July 1994, Barbados joined the newly established Association of Caribbean States (ACS).

As a member of CARICOM, Barbados supported efforts by the United States to implement UN Security Council Resolution 940, designed to facilitate the departure of Haiti's de facto authorities from power. The country agreed to contribute personnel to the multinational force, which restored the democratically elected government of Haiti in October 1994.

In May 1997, Prime Minister Owen Arthur hosted President Clinton and 14 other Caribbean leaders during the first-ever U.S.-regional summit in Bridgetown, Barbados. The summit strengthened the basis for regional cooperation on justice and counternarcotics issues, finance and development, and trade.

Barbados has diplomatic missions headed by resident ambassadors or high commissioners in Canada, the U.K., the U.S., and Venezuela, and at the European Union (Brussels) and the UN. It also has resident consuls general in Toronto, Miami, and New York City. Brazil, Canada, Colombia, China, Guatemala, the U.K., the U.S., and Venezuela have ambassadors or high commissioners resident in Barbados.