Bilateral agreements with several countries of the region, covering diverse areas of cooperation, have underscored the government's interest in strengthening regional ties. The return to Suriname from French Guiana of about 8,000 refugees of the 1986-91 civil war between the military and domestic insurgents has improved relations with French authorities. Longstanding border disputes with Guyana and French Guiana remain unresolved. Negotiations with the Government of Guyana brokered by the Jamaican Prime Minister in 2000 did not produce an agreement, but the countries agreed to restart talks after Guyanese national elections in 2001. In January 2002, the presidents of Suriname and Guyana met in Suriname and agreed to resume negotiations, establishing the Suriname-Guyana border commission. An earlier dispute with Brazil ended amicably after formal demarcation of the border.

In May 1997, then-President Wijdenbosch joined President Clinton and 14 other Caribbean leaders during the first-ever U.S.-regional summit in Bridgetown, Barbados. The summit strengthened the basis for regional cooperation on justice and counternarcotics issues, finance and development, and trade.