Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Siamese Legation Building | Building | 49 | District of Columbia | 38 55 02 N | 077 03 04 W |
| Sibley Memorial Hospital | Hospital | 21 | District of Columbia | 38 54 23 N | 077 00 36 W |
| Sidwell Friends School | School | 104 | District of Columbia | 38 55 58 N | 077 04 34 W |
| Silver Spring Branch (historical) | Stream | | District of Columbia | 38 58 58 N | 077 02 26 W |
| Simms-Lihault House | Building | 38 | District of Columbia | 38 54 28 N | 077 04 14 W |
| Simon Elementary School | School | 20 | District of Columbia | 38 50 09 N | 076 59 60 W |
| Simpson Methodist Church (historical) | Church | 34 | District of Columbia | 38 55 13 N | 077 01 30 W |
| Simpson-Hamline United Methodist Church | Church | 66 | District of Columbia | 38 56 43 N | 077 02 09 W |
| Sims House | Building | 13 | District of Columbia | 38 54 18 N | 077 03 26 W |
| Single Oak | Building | 83 | District of Columbia | 38 55 40 N | 077 03 32 W |
| Sir William Blackstone Statue | Park | 6 | District of Columbia | 38 53 33 N | 077 00 56 W |
| Sir Winston Churchill Statue | Park | 55 | District of Columbia | 38 55 12 N | 077 03 44 W |
| SIS Annex | Building | 119 | District of Columbia | 38 56 10 N | 077 05 25 W |
| Sisters Academy (historical) | School | 8 | District of Columbia | 38 53 06 N | 077 01 17 W |
| Sisters Public School (historical) | School | 14 | District of Columbia | 38 54 06 N | 077 00 43 W |
| Sixteenth Steet Bridge | Bridge | 34 | District of Columbia | 38 56 17 N | 077 02 11 W |
| Sixteenth Street Reservoir (historical) | Reservoir | 82 | District of Columbia | 38 57 17 N | 077 02 14 W |
| Sixth Presbyterian Church | Church | 81 | District of Columbia | 38 57 20 N | 077 02 10 W |
| Slash Run (historical) | Stream | | District of Columbia | 38 55 08 N | 077 02 29 W |
| Slater-Langston Elementary School (historical) | School | 19 | District of Columbia | 38 54 35 N | 077 00 37 W |
| Slidell House (historical) | Building | 19 | District of Columbia | 38 54 01 N | 077 02 14 W |
| Slowe Elementary School | School | 44 | District of Columbia | 38 55 45 N | 076 59 11 W |
| Small Business Administration Building | Building | 21 | District of Columbia | 38 54 14 N | 077 02 02 W |
| Smallwood School (historical) | School | 5 | District of Columbia | 38 52 46 N | 077 00 59 W |
| SMART Program Adult Education Center | School | 25 | District of Columbia | 38 53 17 N | 076 59 07 W |
| Smith Row | Building | 26 | District of Columbia | 38 54 24 N | 077 03 56 W |
| Smith-Morton Row House | Building | 30 | District of Columbia | 38 54 33 N | 077 03 36 W |
| Smiths Park (historical) | Park | 37 | District of Columbia | 38 55 15 N | 077 01 18 W |
| Smithsonian Grounds | Area | 7 | District of Columbia | 38 53 23 N | 077 01 34 W |
| Smithsonian Institution | Building | 9 | District of Columbia | 38 53 19 N | 077 01 33 W |
| Smithsonian Metro Station | Locale | 10 | District of Columbia | 38 53 20 N | 077 01 43 W |
| Smothers Elementary School | School | 32 | District of Columbia | 38 53 37 N | 076 56 18 W |
| Soapstone Valley | Valley | | District of Columbia | 38 56 51 N | 077 03 53 W |
| Soapstone Valley Park | Park | 48 | District of Columbia | 38 56 43 N | 077 03 32 W |
| Society of the Cincinnati Headquarters Building | Building | 23 | District of Columbia | 38 54 40 N | 077 02 51 W |
| Solar Building | Building | 17 | District of Columbia | 38 54 09 N | 077 02 13 W |
| Soldiers Home Cemetery | Cemetery | 89 | District of Columbia | 38 56 40 N | 077 00 31 W |
| Soldiers Home Farm (historical) | Locale | 68 | District of Columbia | 38 56 00 N | 077 00 29 W |
| Soldiers Home Post Office | Post Office | 99 | District of Columbia | 38 56 31 N | 077 00 42 W |
| Sonny Bono Statue | Park | 25 | District of Columbia | 38 54 30 N | 077 02 40 W |
| Sons of the American Revolution Building | Building | 21 | District of Columbia | 38 54 22 N | 077 02 10 W |
| Soul Saving Center Church of God | Church | 32 | District of Columbia | 38 55 08 N | 077 01 38 W |
| Source Main Stage | Building | 29 | District of Columbia | 38 54 52 N | 077 01 55 W |
| Source Warehouse Theatre | Building | 29 | District of Columbia | 38 54 54 N | 077 01 55 W |
| Sousa Middle School | School | 29 | District of Columbia | 38 53 01 N | 076 57 10 W |
| Southeast | Populated Place | 19 | District of Columbia | 38 52 50 N | 076 59 24 W |
| Southeast Branch Library | Building | 23 | District of Columbia | 38 53 02 N | 076 59 48 W |
| Southeast Federal Center | Building | 5 | District of Columbia | 38 52 32 N | 077 00 14 W |
| Southeast Hebrew Temple | Church | 22 | District of Columbia | 38 52 58 N | 076 59 39 W |
| Southeast Quadrant | Civil | 42 | District of Columbia | 38 51 49 N | 076 58 28 W |
| Southeast Station Post Office | Post Office | 24 | District of Columbia | 38 53 07 N | 076 59 47 W |
| Southeastern University | School | 7 | District of Columbia | 38 52 46 N | 077 01 09 W |
| Southern Aid Society Building | Building | 27 | District of Columbia | 38 54 56 N | 077 01 19 W |
| Southern Building | Building | 18 | District of Columbia | 38 54 00 N | 077 02 01 W |
| Southern Railway Building (historical) | Building | 5 | District of Columbia | 38 53 41 N | 077 01 47 W |
| Southwest | Populated Place | 5 | District of Columbia | 38 52 52 N | 077 00 59 W |
| Southwest Branch Library | Building | 5 | District of Columbia | 38 52 44 N | 077 01 01 W |
| Southwest Quadrangle | Locale | | District of Columbia | 38 54 24 N | 077 04 33 W |
| Southwest Quadrant | Civil | 2 | District of Columbia | 38 51 23 N | 077 00 39 W |
| Southwest Station Post Office | Post Office | 5 | District of Columbia | 38 52 40 N | 077 00 36 W |
| Southworth College (historical) | Building | 34 | District of Columbia | 38 54 21 N | 077 04 13 W |
| Spalding Hall | Building | 54 | District of Columbia | 38 55 54 N | 076 59 48 W |
| Spellman Hall | Building | 54 | District of Columbia | 38 55 53 N | 076 59 48 W |
| Spencer Carriage House and Stable | Building | 21 | District of Columbia | 38 54 34 N | 077 02 51 W |
| Spingarn School to Aid Youth | School | 18 | District of Columbia | 38 53 58 N | 076 58 15 W |
| Spingarn Senior High School | School | 18 | District of Columbia | 38 53 58 N | 076 58 15 W |
| Spingarn-Langston Recreation Center | Park | 18 | District of Columbia | 38 53 59 N | 076 58 15 W |
| Spirit of Washington Heliport | Airport | 2 | District of Columbia | 38 52 27 N | 077 01 15 W |
| Spring Branch (historical) | Stream | | District of Columbia | 38 53 16 N | 076 58 06 W |
| Spring Grotto | Park | 13 | District of Columbia | 38 53 27 N | 077 00 37 W |
| Spring Hill Farm (historical) | Locale | 41 | District of Columbia | 38 54 32 N | 077 04 54 W |
| Spring Tavern (historical) | Locale | 33 | District of Columbia | 38 54 42 N | 076 58 34 W |
| Spring Valley | Populated Place | 85 | District of Columbia | 38 56 22 N | 077 05 56 W |
| Spring Valley Park | Park | 76 | District of Columbia | 38 56 14 N | 077 05 55 W |
| Spring Valley Shopping Center | Locale | 74 | District of Columbia | 38 56 42 N | 077 05 44 W |
| Springfield Baptist Church | Church | 26 | District of Columbia | 38 54 33 N | 077 01 11 W |
| Springland House | Building | 87 | District of Columbia | 38 56 29 N | 077 04 06 W |
| Stadium-Armory Metro Station | Locale | 21 | District of Columbia | 38 53 11 N | 076 58 39 W |
| Stan Saloon | Building | 8 | District of Columbia | 38 53 47 N | 077 01 31 W |
| Stanton Elementary School | School | 85 | District of Columbia | 38 51 34 N | 076 58 07 W |
| Stanton Hospital (historical) | Hospital | 16 | District of Columbia | 38 54 04 N | 077 00 48 W |
| Stanton Park | Park | 25 | District of Columbia | 38 53 37 N | 076 59 58 W |
| Stanton Park | Populated Place | 11 | District of Columbia | 38 54 05 N | 076 59 60 W |
| Stead Playground | Park | 24 | District of Columbia | 38 54 37 N | 077 02 15 W |
| Stead Recreation Center | Park | 24 | District of Columbia | 38 54 37 N | 077 02 15 W |
| Stephen A Douglas House (historical) | Building | 16 | District of Columbia | 38 54 04 N | 077 00 49 W |
| Steuart Building (historical) | Building | 18 | District of Columbia | 38 54 11 N | 077 01 09 W |
| Steuart Office Pad | Airport | 93 | District of Columbia | 38 57 30 N | 077 05 17 W |
| Stevens Elementary School | School | 17 | District of Columbia | 38 54 11 N | 077 02 49 W |
| Stevens Playground | Park | 79 | District of Columbia | 38 58 15 N | 077 01 50 W |
| Stevens-Billings Houses | Building | 16 | District of Columbia | 38 54 19 N | 077 03 35 W |
| Stewarts Castle (historical) | Building | 27 | District of Columbia | 38 54 36 N | 077 02 40 W |
| Stickfoot Branch | Stream | | District of Columbia | 38 51 54 N | 077 00 08 W |
| Stockton Hall - George Washington University | Building | 19 | District of Columbia | 38 53 55 N | 077 02 41 W |
| Stoddert Elementary School | School | 92 | District of Columbia | 38 55 22 N | 077 04 42 W |
| Stoddert Playground | Park | 92 | District of Columbia | 38 55 22 N | 077 04 41 W |
| Stoddert Recreation Center | Park | 93 | District of Columbia | 38 55 22 N | 077 04 39 W |
| Stone House (historical) | Building | 11 | District of Columbia | 38 53 50 N | 077 01 56 W |
| Stott Company Building (historical) | Building | 14 | District of Columbia | 38 53 56 N | 077 01 57 W |
| Stott Station (historical) | Locale | 65 | District of Columbia | 38 57 23 N | 077 00 15 W |
| Stuart-Hobson Middle School | School | 19 | District of Columbia | 38 53 47 N | 076 59 60 W |
| Student Health & Fitness Center | Building | 55 | District of Columbia | 38 56 16 N | 076 59 53 W |
| Studio Theater | Building | 29 | District of Columbia | 38 54 38 N | 077 01 57 W |
| Success (historical) | Civil | 37 | District of Columbia | 38 55 11 N | 077 01 49 W |
| Sulgrave Club | Building | 26 | District of Columbia | 38 54 34 N | 077 02 33 W |
| Sulpician Seminary | School | 60 | District of Columbia | 38 55 52 N | 076 59 55 W |
| Summer House | Building | 11 | District of Columbia | 38 53 28 N | 077 00 38 W |
| Summy House (historical) | Building | 55 | District of Columbia | 38 56 17 N | 077 01 58 W |
| Supreme Court | Building | 27 | District of Columbia | 38 53 25 N | 077 00 16 W |
| Sursum Corda Community Library | Building | 24 | District of Columbia | 38 54 21 N | 077 00 48 W |