Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| School Number 124 (historical) | School | 198 | Will | 41 31 56 N | 087 56 06 W |
| School Number 97 (historical) | School | 198 | Will | 41 37 34 N | 088 02 30 W |
| Scott School (historical) | Locale | 198 | Grundy | 41 07 20 N | 088 31 42 W |
| Seaborn Cemetery | Cemetery | 198 | Pike | 39 50 02 N | 090 50 31 W |
| Seventh Avenue Elementary School | School | 198 | Cook | 41 48 04 N | 087 51 58 W |
| Seventh Day Adventist Church | Church | 198 | Fulton | 40 32 38 N | 090 02 08 W |
| Sexson Corner | Populated Place | 198 | Shelby | 39 23 22 N | 088 31 05 W |
| Shelbyville Free Public Library | Building | 198 | Shelby | 39 24 27 N | 088 47 38 W |
| Shelbyville Historic District | Park | 198 | Shelby | 39 24 32 N | 088 47 45 W |
| Shepherd of the Hill Lutheran Church | Church | 198 | Will | 41 35 29 N | 088 02 30 W |
| Sherwood Park | Park | 198 | Lake | 42 10 43 N | 087 49 24 W |
| Shriners Hospital | Hospital | 198 | Cook | 41 55 11 N | 087 47 36 W |
| Skinner Airport | Airport | 198 | La Salle | 41 14 15 N | 088 55 35 W |
| Smalleytown School (historical) | School | 198 | Macoupin | 39 04 21 N | 089 58 42 W |
| Smoky Row School (historical) | School | 198 | Montgomery | 39 15 42 N | 089 13 30 W |
| Somme Prairie Nature Preserve | Park | 198 | Cook | 42 08 30 N | 087 50 16 W |
| Sononauk Lake (historical) | Lake | 198 | DeKalb | 41 38 12 N | 088 37 54 W |
| Sooy Cemetery | Cemetery | 198 | Morgan | 39 35 20 N | 090 10 43 W |
| South Basco Cemetery | Cemetery | 198 | Hancock | 40 18 37 N | 091 12 04 W |
| South Hall | Building | 198 | Will | 41 36 10 N | 088 04 58 W |
| South Otter Townhall | Building | 198 | Macoupin | 39 23 43 N | 089 51 52 W |
| South Point Shopping Center | Locale | 198 | Cook | 42 05 47 N | 087 54 30 W |
| South Prairie School (historical) | School | 198 | Henderson | 40 44 58 N | 090 55 60 W |
| Southland Acres (subdivision) | Populated Place | 198 | Douglas | 39 47 22 N | 088 17 05 W |
| Spangler Cemetery | Cemetery | 198 | Macon | 39 51 03 N | 088 53 54 W |
| Spoon Lake | Reservoir | 198 | Knox | 40 57 04 N | 090 07 29 W |
| Spoon Lake Dam | Dam | 198 | Knox | 40 57 04 N | 090 07 29 W |
| Spring Bluff Elementary School | School | 198 | Lake | 42 28 59 N | 087 49 32 W |
| Spring Creek Plaza Shopping Center | Locale | 198 | Macon | 39 52 23 N | 088 58 20 W |
| Spring Creek School (historical) | School | 198 | Whiteside | 41 45 48 N | 090 10 24 W |