Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Schuyler Creek | Stream | | Butler | 42 52 26 N | 092 41 38 W |
| Schwartz Chiropractic Clinic | Hospital | 448 | Dickinson | 43 25 23 N | 095 06 07 W |
| Schwenck Family Plot (historical) | Cemetery | 348 | Wright | 42 41 00 N | 093 57 41 W |
| Schwenker Lake Dam | Dam | 268 | Jackson | 42 14 58 N | 090 46 15 W |
| Schwerin Landing Strip | Airport | 326 | Bremer | 42 49 30 N | 092 09 55 W |
| Schwob Marsh State Game Management Area | Park | 347 | Kossuth | 43 19 18 N | 094 07 16 W |
| Science and Classroom Building | Building | 261 | Polk | 41 37 15 N | 093 36 23 W |
| Science and Education Building | Building | 284 | Polk | 41 35 00 N | 093 39 41 W |
| Science and Technology Center | Building | 446 | Sioux | 43 04 56 N | 096 10 02 W |
| Science Center of Iowa | Building | 273 | Polk | 41 34 58 N | 093 40 46 W |
| Science Division Annex | Building | 260 | Polk | 41 37 15 N | 093 36 24 W |
| Science Hall | Building | 217 | Henry | 40 58 25 N | 091 33 26 W |
| Science Hall | Building | 439 | Sioux | 42 59 52 N | 096 03 26 W |
| Science Hall | Building | 289 | Story | 42 01 45 N | 093 38 47 W |
| Science Hall II | Building | 288 | Story | 42 01 47 N | 093 38 47 W |
| Sciola | Populated Place | 334 | Montgomery | 41 02 02 N | 094 59 08 W |
| Sciola Baptist Cemetery | Cemetery | 332 | Montgomery | 41 02 03 N | 094 59 09 W |
| Sciola Post Office (historical) | Post Office | 322 | Montgomery | 41 01 58 N | 094 59 46 W |
| Scotch Grove | Populated Place | 267 | Jones | 42 10 22 N | 091 06 28 W |
| Scotch Grove (historical) | Locale | 267 | Jones | 42 10 22 N | 091 06 28 W |
| Scotch Grove Cemetery | Cemetery | 276 | Jones | 42 09 57 N | 091 03 50 W |
| Scotch Grove Church | Church | 275 | Jones | 42 09 45 N | 091 03 54 W |
| Scotch Grove Post Office (historical) | Post Office | 267 | Jones | 42 10 22 N | 091 06 28 W |
| Scotch Ridge | Populated Place | 284 | Warren | 41 28 21 N | 093 33 31 W |
| Scotch Ridge Cemetery | Cemetery | 284 | Warren | 41 28 24 N | 093 33 29 W |
| Scotch Ridge United Presbyterian Church | Church | 284 | Warren | 41 28 24 N | 093 33 31 W |
| Scott | Locale | 332 | Floyd | 42 55 17 N | 092 56 59 W |
| Scott | Populated Place | 351 | Fayette | 42 42 07 N | 091 45 56 W |
| Scott Cemetery | Cemetery | 222 | Henry | 40 59 40 N | 091 33 11 W |
| Scott Cemetery | Cemetery | 223 | Johnson | 41 36 13 N | 091 26 39 W |
| Scott Cemetery | Cemetery | 276 | Jones | 42 09 57 N | 091 03 50 W |
| Scott Center Post Office (historical) | Post Office | 362 | Fayette | 42 41 26 N | 091 49 29 W |
| Scott Chapel | Building | 291 | Polk | 41 36 12 N | 093 39 10 W |
| Scott Community College | School | 204 | Scott | 41 32 53 N | 090 28 07 W |
| Scott Community College Library | Building | 203 | Scott | 41 32 50 N | 090 28 05 W |
| Scott County | Civil | 226 | Scott | 41 38 00 N | 090 38 01 W |
| Scott County Community College | School | 171 | Scott | 41 31 15 N | 090 34 57 W |
| Scott County Courthouse | Building | 178 | Scott | 41 31 26 N | 090 34 45 W |
| Scott County Library | Building | 224 | Scott | 41 35 04 N | 090 46 24 W |
| Scott County Library | Building | 242 | Scott | 41 41 51 N | 090 34 57 W |
| Scott County Library | Building | 236 | Scott | 41 38 25 N | 090 35 02 W |
| Scott County Library | Building | 183 | Scott | 41 36 01 N | 090 20 37 W |
| Scott County Park | Park | 225 | Scott | 41 42 41 N | 090 31 47 W |
| Scott County Sheriffs Office | Building | 178 | Scott | 41 31 26 N | 090 34 45 W |
| Scott Field Municipal Airport | Airport | 371 | Fayette | 42 59 04 N | 091 47 25 W |
| Scott Island | Island | 181 | Jackson | 42 19 09 N | 090 25 35 W |
| Scott Park | Park | 218 | Johnson | 41 39 18 N | 091 28 43 W |
| Scott Post Office (historical) | Post Office | 352 | Fayette | 42 42 05 N | 091 45 51 W |
| Scott Post Office (historical) | Post Office | 313 | Floyd | 42 56 60 N | 092 56 11 W |
| Scott School | School | 340 | Madison | 41 17 16 N | 093 57 18 W |
| Scott School | School | 242 | Polk | 41 34 49 N | 093 34 15 W |
| Scott State Wildlife Management Area | Park | 284 | Fremont | 40 51 41 N | 095 48 01 W |
| Scott Street Dam | Dam | 232 | Polk | 41 34 48 N | 093 36 42 W |
| Scott Township Ditch | Canal | 285 | Fremont | 40 50 00 N | 095 48 45 W |
| Scottswood | Locale | 354 | Pottawattamie | 41 14 46 N | 095 47 07 W |
| Scottswood Post Office (historical) | Post Office | 371 | Pottawattamie | 41 16 00 N | 095 45 58 W |
| Scout Park | Park | 428 | Buena Vista | 42 38 26 N | 095 12 47 W |
| Scout Park | Park | 203 | Scott | 41 36 30 N | 090 20 45 W |
| Scranton | Locale | 360 | Greene | 42 01 10 N | 094 32 41 W |
| Scranton | Populated Place | 359 | Greene | 42 01 21 N | 094 32 43 W |
| Scranton Cemetery | Cemetery | 369 | Greene | 42 01 50 N | 094 34 43 W |
| Scranton City Town Hall | Building | 360 | Greene | 42 01 17 N | 094 32 43 W |
| Scranton Consolidated School | School | 358 | Greene | 42 01 20 N | 094 32 37 W |
| Scranton Post Office | Post Office | 360 | Greene | 42 01 17 N | 094 32 43 W |
| Scranton Public Library | Building | 360 | Greene | 42 01 15 N | 094 32 43 W |
| Seamans Center for the Engineering Arts and Sciences | Building | 202 | Johnson | 41 39 34 N | 091 32 14 W |
| Sears Sports Complex | Locale | 389 | Union | 41 03 15 N | 094 21 14 W |
| Searsboro | Locale | 257 | Poweshiek | 41 34 50 N | 092 42 13 W |
| Searsboro | Populated Place | 257 | Poweshiek | 41 34 50 N | 092 42 13 W |
| Searsboro Community Center | Building | 257 | Poweshiek | 41 34 50 N | 092 42 13 W |
| Searsboro Fire Department | Building | 257 | Poweshiek | 41 34 50 N | 092 42 13 W |
| Searsboro International Order of Odd Fellows Cemetery | Cemetery | 275 | Poweshiek | 41 34 57 N | 092 42 06 W |
| Searsboro Post Office | Post Office | 257 | Poweshiek | 41 34 50 N | 092 42 13 W |
| Searsboro Sully Lynville School | School | 275 | Poweshiek | 41 34 56 N | 092 41 60 W |
| Seashore Hall | Building | 207 | Johnson | 41 39 42 N | 091 31 53 W |
| Seater Family Plot | Cemetery | 374 | Worth | 43 26 60 N | 093 13 01 W |
| Seaton Post Office (historical) | Post Office | 345 | Fayette | 42 44 45 N | 091 49 12 W |
| Seay Cemetery | Cemetery | 268 | Jasper | 41 31 56 N | 093 06 25 W |
| Second Baptist Church | Church | 297 | Appanoose | 40 43 48 N | 092 52 05 W |
| Second Baptist Church | Church | 180 | Clinton | 41 50 57 N | 090 11 42 W |
| Second Baptist Church | Church | 218 | Henry | 40 58 13 N | 091 33 29 W |
| Second Baptist Church | Church | 162 | Lee | 40 37 31 N | 091 21 06 W |
| Second Baptist Church | Church | 273 | Marshall | 42 03 06 N | 092 54 11 W |
| Second Baptist Church | Church | 215 | Wapello | 41 01 05 N | 092 24 31 W |
| Second Baptist Church | Church | 337 | Webster | 42 30 08 N | 094 10 23 W |
| Second Christian Reformed Church | Church | 266 | Marion | 41 24 16 N | 092 54 55 W |
| Second Creek | Stream | | Boone | 42 00 30 N | 093 55 24 W |
| Second Reformed Church | Church | 267 | Marion | 41 24 18 N | 092 55 05 W |
| Secor (historical) | Populated Place | 288 | Hardin | 42 18 40 N | 093 04 19 W |
| Secor Post Office (historical) | Post Office | 288 | Hardin | 42 18 40 N | 093 04 19 W |
| Security Building | Building | 292 | Polk | 41 36 12 N | 093 39 04 W |
| Security Office | Building | 268 | Dubuque | 42 29 54 N | 090 41 29 W |
| Sedan | Populated Place | 286 | Appanoose | 40 39 25 N | 092 50 01 W |
| Sedan (historical) | Locale | 286 | Appanoose | 40 39 25 N | 092 50 01 W |
| Sedan Bottoms | Park | 253 | Appanoose | 40 40 00 N | 092 45 46 W |
| Sedan Post Office (historical) | Post Office | 286 | Appanoose | 40 39 25 N | 092 50 01 W |
| Sedgewich (historical) | Locale | 327 | Decatur | 40 36 33 N | 093 56 22 W |
| Sedgewick Post Office (historical) | Post Office | 342 | Decatur | 40 36 16 N | 093 56 29 W |
| Sedore Cemetery | Cemetery | 192 | Wapello | 40 56 05 N | 092 18 21 W |
| Seed of Life Family Church | Church | 278 | Bremer | 42 43 03 N | 092 28 24 W |
| Seed Sciences Building | Building | 284 | Story | 42 01 45 N | 093 38 36 W |
| Seeds of Faith Lutheran Church | Church | 279 | Linn | 41 55 25 N | 091 25 13 W |
| Seegmiller Cemetery | Cemetery | 380 | Winneshiek | 43 24 27 N | 091 43 59 W |
| Seegmiller Cemetery | Cemetery | 378 | Winneshiek | 43 24 28 N | 091 43 60 W |
| Seeley Creek Timber | Park | 392 | Guthrie | 41 39 30 N | 094 36 26 W |
| Seely Creek | Stream | | Guthrie | 41 41 27 N | 094 32 46 W |
| Seerley Hall | Building | 282 | Black Hawk | 42 30 50 N | 092 27 27 W |
| Seerley Park | Park | 278 | Black Hawk | 42 30 59 N | 092 27 04 W |
| Seevers (historical) | Locale | 259 | Jasper | 41 39 06 N | 093 12 48 W |
| Seevers Post Office (historical) | Post Office | 259 | Jasper | 41 39 06 N | 093 12 48 W |