Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Southwood Lutheran Church | Church | 374 | Lancaster | 40 45 38 N | 096 40 59 W |
| Sovereign Grace Church | Church | 355 | Douglas | 41 18 15 N | 096 03 58 W |
| Sowards Ranch | Locale | 1195 | Sheridan | 42 13 24 N | 102 13 42 W |
| Sowbelly Canyon | Valley | | Sioux | 42 45 29 N | 103 49 24 W |
| Sowbelly Creek | Stream | | Sioux | 42 50 51 N | 103 48 58 W |
| Spade Ranch | Locale | 1177 | Sheridan | 42 18 20 N | 102 05 21 W |
| Spade Ranch Historical Marker | Park | 1195 | Sheridan | 42 03 31 N | 102 16 51 W |
| Spade School | School | 1189 | Sheridan | 42 19 39 N | 102 07 14 W |
| Spahn Ranch | Locale | 1127 | Arthur | 41 38 20 N | 101 48 58 W |
| Spahnle Cemetery | Cemetery | 386 | Otoe | 40 46 14 N | 096 27 48 W |
| Spahr Ranch | Locale | 1409 | Banner | 41 37 29 N | 104 00 18 W |
| Spalding | Locale | 573 | Greeley | 41 41 04 N | 098 22 01 W |
| Spalding | Populated Place | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Academy | School | 582 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding City Park | Park | 582 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding City Park Campground | Locale | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Co-op Elevator | Locale | 616 | Greeley | 41 32 55 N | 098 31 52 W |
| Spalding Community Clinic | Hospital | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Cooperative Elevator | Locale | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Cooperative Elevator | Locale | 598 | Valley | 41 29 43 N | 098 46 23 W |
| Spalding Dam Site Campground | Locale | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Election Precinct | Civil | 597 | Greeley | 41 40 09 N | 098 23 38 W |
| Spalding Post Office | Post Office | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Public Library | Building | 581 | Greeley | 41 41 20 N | 098 21 48 W |
| Spalding Public Schools | School | 584 | Greeley | 41 41 25 N | 098 21 50 W |
| Spall Lake | Lake | 1040 | Cherry | 42 57 30 N | 101 53 01 W |
| Spanish Assembly of God Church | Church | 1210 | Box Butte | 42 06 04 N | 102 52 51 W |
| Spanish Assembly of God Church | Church | 855 | Lincoln | 41 08 39 N | 100 46 22 W |
| Spanish-American War Veterans Memorial | Park | 439 | Platte | 41 25 13 N | 097 22 02 W |
| Spannuth School (historical) | School | 866 | Lincoln | 41 10 10 N | 100 17 02 W |
| Sparks | Populated Place | 793 | Cherry | 42 56 28 N | 100 15 21 W |
| Sparks Cemetery | Cemetery | 794 | Cherry | 42 56 24 N | 100 14 48 W |
| Sparks Hall | Building | 1045 | Dawes | 42 49 12 N | 103 00 03 W |
| Sparks Post Office | Post Office | 793 | Cherry | 42 56 28 N | 100 15 21 W |
| Sparks Public School | School | 793 | Cherry | 42 56 28 N | 100 15 21 W |
| Sparks Store and RV Camp | Locale | 793 | Cherry | 42 56 28 N | 100 15 21 W |
| Sparta | Populated Place | 502 | Knox | 42 39 19 N | 097 58 25 W |
| Sparta Post Office (historical) | Post Office | 502 | Knox | 42 39 19 N | 097 58 25 W |
| Spaulding Park | Park | 320 | Douglas | 41 17 37 N | 095 57 30 W |
| Spear Flat | Flat | 1378 | Banner | 41 40 45 N | 104 00 16 W |
| Spear-Diamond Ranch | Locale | 1426 | Sioux | 42 08 57 N | 103 38 56 W |
| Speas Dam | Dam | 1277 | Sioux | 42 45 36 N | 103 34 14 W |
| Speas Reservoir | Reservoir | 1277 | Sioux | 42 45 36 N | 103 34 14 W |
| Specialty Clinic West | Hospital | 504 | York | 40 52 50 N | 097 35 36 W |
| Specialty Services Pavilion | Building | 350 | Douglas | 41 15 16 N | 095 58 41 W |
| Speck Lake | Lake | 1028 | Cherry | 42 19 40 N | 101 16 47 W |
| Speckel-Meir Lake | Lake | 1046 | Cherry | 42 20 41 N | 101 22 37 W |
| Speedway School | School | 492 | Butler | 41 09 21 N | 097 06 02 W |
| Speer Ranch | Locale | 1179 | Sheridan | 42 17 47 N | 102 25 27 W |
| Speiser Election Precinct | Civil | 326 | Richardson | 40 02 28 N | 095 56 50 W |
| Spekes Temple African Methodist Episcopal Zion Church | Church | 316 | Douglas | 41 17 29 N | 095 56 56 W |
| Spelts | Populated Place | 616 | Valley | 41 35 48 N | 098 50 50 W |
| Spencer | Populated Place | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer (historical) | Locale | 473 | Boyd | 42 52 40 N | 098 41 41 W |
| Spencer Dam | Dam | 461 | Holt | 42 48 30 N | 098 39 25 W |
| Spencer Dam | Dam | 460 | Holt | 42 48 17 N | 098 39 35 W |
| Spencer Dam | Dam | 792 | Red Willow | 40 16 00 N | 100 43 02 W |
| Spencer Elementary School | School | 512 | Boyd | 42 52 32 N | 098 42 02 W |
| Spencer Fire Department | Building | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer Lake | Lake | 880 | Cherry | 42 36 05 N | 100 37 54 W |
| Spencer Medical Clinic | Hospital | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer Park - Fairgrounds Campground | Locale | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer Park (historical) | Locale | 583 | Adams | 40 34 35 N | 098 22 33 W |
| Spencer Park School (historical) | School | 748 | Custer | 41 22 24 N | 099 28 35 W |
| Spencer Police Department | Building | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer Post Office | Post Office | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer Ranch | Locale | 1127 | Arthur | 41 35 25 N | 101 50 19 W |
| Spencer Ranch | Locale | 877 | Cherry | 42 18 06 N | 100 35 10 W |
| Spencer Reservoir | Reservoir | 792 | Red Willow | 40 16 00 N | 100 43 02 W |
| Spencer Township Library | Building | 514 | Boyd | 42 52 26 N | 098 42 05 W |
| Spencer-Naper High School | School | 512 | Boyd | 42 52 32 N | 098 42 02 W |
| Spieker Dam | Dam | 560 | Boone | 41 49 18 N | 098 05 49 W |
| Spieker Reservoir | Reservoir | 560 | Boone | 41 49 18 N | 098 05 49 W |
| Spiker | Locale | 410 | Washington | 41 36 26 N | 096 18 35 W |
| Spiker Post Office (historical) | Post Office | 410 | Washington | 41 36 26 N | 096 18 35 W |
| Spikerush State Wildlife Management Area | Park | 497 | York | 40 54 30 N | 097 29 11 W |
| Spillway Bay | Bay | 998 | Keith | 41 12 25 N | 101 40 22 W |
| Spillway Bay Campground | Locale | 1013 | Keith | 41 12 27 N | 101 40 12 W |
| Spillway Park | Park | 1025 | Keith | 41 11 45 N | 101 39 27 W |
| Spititual Assembly of the Baha'i | Church | 374 | Lancaster | 40 48 47 N | 096 38 10 W |
| Splash Arena | Park | 1185 | Scotts Bluff | 41 52 38 N | 103 39 24 W |
| Split Lake | Lake | 1121 | Grant | 41 52 40 N | 101 42 19 W |
| Spohn Canal | Canal | 1043 | Garden | 41 26 07 N | 102 26 42 W |
| Sponheinmer Dam | Dam | 366 | Lancaster | 40 58 12 N | 096 34 37 W |
| Sponheinmer Reservoir | Reservoir | 366 | Lancaster | 40 58 12 N | 096 34 37 W |
| Spook Canyon | Valley | | Scotts Bluff | 41 48 35 N | 103 49 37 W |
| Sports Medicine Institute of Nebraska | Building | 401 | Lancaster | 40 47 53 N | 096 37 34 W |
| Sportsman Field | Park | 758 | Dawson | 40 52 18 N | 099 58 41 W |
| Spotted Horse Valley | Basin | 1073 | Arthur | 41 27 46 N | 101 34 32 W |
| Spotted Tail Campground | Locale | 1154 | Dawes | 42 45 26 N | 102 59 22 W |
| Spotted Tail Cemetery | Cemetery | 653 | Keya Paha | 42 58 48 N | 099 19 58 W |
| Spotted Tail Creek | Stream | | Keya Paha | 42 55 49 N | 099 19 28 W |
| Spotted Tail School (historical) | School | 647 | Keya Paha | 42 58 50 N | 099 19 34 W |
| Spotted Tail Trailhead | Locale | 1142 | Dawes | 42 45 24 N | 102 59 18 W |
| Spottedtail Community Hall | Locale | 1265 | Furnas | 42 02 41 N | 103 48 53 W |
| Spottedtail Creek | Stream | | Sioux | 41 57 07 N | 103 48 38 W |
| Sprague | Locale | 382 | Lancaster | 40 37 27 N | 096 44 44 W |
| Sprague | Populated Place | 388 | Lancaster | 40 37 33 N | 096 44 41 W |
| Sprague Community Church | Church | 388 | Lancaster | 40 37 33 N | 096 44 41 W |
| Sprague Park | Park | 565 | Hall | 40 56 30 N | 098 19 51 W |
| Sprague Post Office | Post Office | 388 | Lancaster | 40 37 33 N | 096 44 41 W |
| Sprick Dam | Dam | 376 | Washington | 41 35 60 N | 096 17 37 W |
| Sprick Reservoir | Reservoir | 376 | Washington | 41 35 60 N | 096 17 37 W |
| Spring Bank Post Office (historical) | Post Office | 454 | Dixon | 42 24 60 N | 096 48 16 W |
| Spring Branch | Stream | | Hitchcock | 40 09 56 N | 101 19 02 W |
| Spring Branch | Stream | | Lancaster | 40 36 55 N | 096 45 52 W |
| Spring Branch | Stream | | Rock | 42 28 40 N | 099 41 03 W |
| Spring Branch | Stream | | Sherman | 41 05 15 N | 099 05 35 W |
| Spring Branch | Stream | | Thayer | 40 03 21 N | 097 25 58 W |
| Spring Branch | Stream | | Wayne | 42 03 06 N | 097 24 26 W |