Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Senecaville | Populated Place | 272 | Guernsey | 39 56 03 N | 081 27 44 W |
| Senecaville Cemetery | Cemetery | 274 | Guernsey | 39 56 22 N | 081 27 47 W |
| Senecaville Dam | Dam | 254 | Guernsey | 39 55 30 N | 081 26 07 W |
| Senecaville Lake | Reservoir | 254 | Guernsey | 39 55 30 N | 081 26 07 W |
| Senecaville National Fish Hatchery | Locale | 250 | Guernsey | 39 55 32 N | 081 26 15 W |
| Senecaville Post Office | Post Office | 274 | Guernsey | 39 56 05 N | 081 27 44 W |
| Senior | Populated Place | 213 | Warren | 39 23 09 N | 084 05 22 W |
| Sensenbrenner Park | Park | 226 | Franklin | 39 58 05 N | 083 00 05 W |
| Sentinel | Populated Place | 314 | Ashtabula | 41 38 05 N | 080 43 17 W |
| Sentinel Point | Cape | 175 | Lucas | 41 33 44 N | 083 38 42 W |
| Sentinel Post Office (historical) | Post Office | 314 | Ashtabula | 41 38 05 N | 080 43 19 W |
| Sequoia Golf Course | Locale | 212 | Lake | 41 38 40 N | 081 23 06 W |
| Serpent Mound | Summit | 230 | Adams | 39 01 25 N | 083 25 53 W |
| Serpent Mound Mission | Church | 234 | Adams | 39 00 41 N | 083 24 28 W |
| Serpent Mound State Memorial | Park | 240 | Adams | 39 01 27 N | 083 25 47 W |
| Sesquicentennial Chapel | Church | 272 | Butler | 39 30 25 N | 084 43 60 W |
| Seth Corners | Locale | 348 | Clark | 40 01 48 N | 083 58 57 W |
| Seton High School | School | 267 | Hamilton | 39 06 47 N | 084 34 39 W |
| Setterlin Hall | Building | 238 | Franklin | 39 57 18 N | 082 56 14 W |
| Setty Branch | Stream | | Highland | 39 04 36 N | 083 27 13 W |
| Sevakeen Lake | Lake | 362 | Columbiana | 40 52 29 N | 080 56 27 W |
| Seven Hills | Populated Place | 269 | Cuyahoga | 41 23 43 N | 081 40 34 W |
| Seven Hills Church of God | Church | 262 | Hamilton | 39 16 28 N | 084 34 12 W |
| Seven Hills City Hall | Building | 338 | Cuyahoga | 41 22 05 N | 081 41 02 W |
| Seven Hills Golf Course | Locale | 351 | Stark | 40 57 04 N | 081 18 17 W |
| Seven Hills Police Station | Building | | Cuyahoga | 41 22 05 N | 081 41 02 W |
| Seven Hills School | School | 350 | Cuyahoga | 41 21 59 N | 081 40 49 W |
| Seven Hills School | School | 260 | Hamilton | 39 16 31 N | 084 33 32 W |
| Seven Mile | Populated Place | 199 | Butler | 39 28 48 N | 084 33 07 W |
| Seven Mile Creek | Stream | | Hamilton | 39 02 24 N | 084 21 16 W |
| Seven Mile Post Office | Post Office | 200 | Butler | 39 28 50 N | 084 33 05 W |
| Seven Mile United Methodist Church | Church | 198 | Butler | 39 28 52 N | 084 33 16 W |
| Seven Spring Farm (historical) | Locale | 316 | Knox | 40 24 10 N | 082 13 19 W |
| Seven Springs Lake | Reservoir | 305 | Medina | 41 07 24 N | 081 48 29 W |
| Seven Springs Lake Dam | Dam | 305 | Medina | 41 07 24 N | 081 48 29 W |
| Sevenmile Creek | Stream | | Preble | 39 27 50 N | 084 33 20 W |
| Seventh Avenue Community Baptist Church | Church | 235 | Franklin | 39 59 26 N | 083 00 20 W |
| Seventh Church of Christ Scientist | Church | 182 | Cuyahoga | 41 34 24 N | 081 34 46 W |
| Seventh Day Adventist Church | Church | 268 | Auglaize | 40 32 36 N | 084 23 42 W |
| Seventh Day Adventist Church | Church | 348 | Crawford | 40 43 57 N | 082 47 42 W |
| Seventh Day Adventist Church | Church | 230 | Defiance | 41 17 19 N | 084 45 54 W |
| Seventh Day Adventist Church | Church | 252 | Licking | 40 03 11 N | 082 24 16 W |
| Seventh Day Adventist Church | Church | 342 | Portage | 41 09 29 N | 081 15 33 W |
| Seventh Day Adventist Church | Church | 268 | Tuscarawas | 40 29 25 N | 081 27 33 W |
| Seventh Day Adventist Church | Church | 291 | Wayne | 40 48 11 N | 081 56 15 W |
| Seventh Day Adventist Temple | Church | 207 | Henry | 41 23 36 N | 084 07 42 W |
| Seventh Day Adventist Temple Emmanuel | Church | 313 | Mahoning | 41 05 15 N | 080 40 17 W |
| Seventh Day Cemetery | Cemetery | 312 | Shelby | 40 26 21 N | 084 02 59 W |
| Seventh Day Church of God (historical) | Church | 277 | Trumbull | 41 13 13 N | 080 47 54 W |
| Seventh Presbyterian Church | Church | 247 | Hamilton | 39 07 46 N | 084 28 25 W |
| Seventh Street Church of Christ | Church | 211 | Morgan | 39 38 52 N | 081 51 06 W |
| Seventyfive North Industrial Park | Locale | 274 | Montgomery | 39 50 28 N | 084 11 05 W |
| Severance Hall | Building | 208 | Cuyahoga | 41 30 23 N | 081 36 34 W |
| Severance Hall | Building | 329 | Wayne | 40 48 34 N | 081 56 09 W |
| Severance Town Center Shopping Center | Locale | 297 | Cuyahoga | 41 31 01 N | 081 33 03 W |
| Severance-Millikin School | School | 299 | Cuyahoga | 41 30 48 N | 081 32 48 W |
| Seville | Populated Place | 298 | Medina | 41 00 36 N | 081 51 44 W |
| Seville Branch Medina County District Library | Building | 298 | Medina | 41 00 37 N | 081 51 44 W |
| Seville Elementary School | School | 300 | Medina | 41 00 34 N | 081 51 37 W |
| Seville Post Office | Post Office | 298 | Medina | 41 00 35 N | 081 51 44 W |
| Seville Presbyterian Church | Church | 307 | Medina | 41 00 49 N | 081 51 44 W |
| Seville United Methodist Church | Church | 306 | Medina | 41 00 37 N | 081 52 01 W |
| Seward | Populated Place | 230 | Fulton | 41 41 59 N | 084 02 11 W |
| Seward Post Office (historical) | Post Office | 230 | Fulton | 41 42 00 N | 084 02 10 W |
| Seward School (historical) | School | 227 | Fulton | 41 42 02 N | 084 01 14 W |
| Sewell Cemetery | Cemetery | 283 | Clinton | 39 22 42 N | 083 57 19 W |
| Sewell Run | Stream | | Clinton | 39 24 10 N | 083 58 29 W |
| Sewellsville | Populated Place | 402 | Belmont | 40 05 53 N | 081 12 47 W |
| Sewellsville Cemetery | Cemetery | 398 | Belmont | 40 05 50 N | 081 12 42 W |
| Sewellsville Methodist Episcopal Church | Church | 400 | Belmont | 40 05 50 N | 081 12 44 W |
| Sewellsville Post Office (historical) | Post Office | 402 | Belmont | 40 05 55 N | 081 12 49 W |
| Sexton Cemetery | Cemetery | 223 | Ashtabula | 41 48 21 N | 080 54 13 W |
| Sexton Ditch | Canal | 337 | Madison | 39 46 41 N | 083 34 32 W |
| Sexton Junior High School | School | 298 | Mahoning | 41 03 12 N | 080 35 48 W |
| Seybert Church | Church | 232 | Sandusky | 41 16 34 N | 082 50 54 W |
| Seyforth Cemetery | Cemetery | 221 | Warren | 39 16 28 N | 084 14 04 W |
| Seymore Cemetery | Cemetery | 207 | Scioto | 38 46 46 N | 083 02 17 W |
| Seymoreville (historical) | Populated Place | 187 | Ross | 39 20 40 N | 082 56 50 W |
| Seymour Creek | Stream | | Huron | 41 16 50 N | 082 40 36 W |
| Seymour Nature Preserve | Park | 176 | Hamilton | 39 11 50 N | 084 29 55 W |
| Seymour Plaza Shopping Center | Locale | 171 | Hamilton | 39 11 32 N | 084 27 52 W |
| Seymour Run | Stream | | Ashland | 40 44 46 N | 082 21 42 W |
| Shaaray Torah Synagogue | Church | 353 | Stark | 40 49 50 N | 081 22 26 W |
| Shackleton | Populated Place | 332 | Highland | 39 10 32 N | 083 40 41 W |
| Shadblow Reservable Area | Locale | 281 | Franklin | 40 04 32 N | 082 52 40 W |
| Shade | Populated Place | 246 | Athens | 39 13 33 N | 082 02 19 W |
| Shade Bridge | Bridge | 251 | Fairfield | 39 36 27 N | 082 31 46 W |
| Shade Creek | Stream | | Wayne | 40 55 29 N | 082 00 27 W |
| Shade Post Office | Post Office | 244 | Athens | 39 13 30 N | 082 02 20 W |
| Shade River | Populated Place | 177 | Meigs | 39 04 06 N | 081 48 51 W |
| Shade River | Stream | | Athens | 39 15 01 N | 082 01 23 W |
| Shade River | Stream | | Meigs | 39 04 03 N | 081 48 49 W |
| Shade Valley Lake | Reservoir | 183 | Meigs | 39 06 29 N | 081 52 15 W |
| Shademoore | Populated Place | 147 | Hamilton | 39 08 17 N | 084 22 06 W |
| Shadeville | Populated Place | 214 | Franklin | 39 49 56 N | 083 00 12 W |
| Shadeville Post Office (historical) | Post Office | 214 | Franklin | 39 49 55 N | 083 00 10 W |
| Shadley Cemetery | Cemetery | 306 | Hardin | 40 42 40 N | 083 48 15 W |
| Shadley Valley Cemetery | Cemetery | 323 | Knox | 40 31 31 N | 082 17 08 W |
| Shadley Valley Creek | Stream | | Knox | 40 29 57 N | 082 17 21 W |
| Shadow Lake | Reservoir | 237 | Warren | 39 24 00 N | 084 18 60 W |
| Shadow Lake Dam | Dam | 237 | Warren | 39 24 00 N | 084 18 60 W |
| Shadow of the Almighty Church | Church | 162 | Scioto | 38 44 03 N | 082 59 39 W |
| Shady Acres Golf Course | Locale | 235 | Hancock | 41 06 17 N | 083 47 17 W |
| Shady Bend | Populated Place | 241 | Coshocton | 40 16 04 N | 081 38 25 W |
| Shady Bowl Speedway | Locale | 329 | Champaign | 40 15 28 N | 083 56 09 W |
| Shady Corner School (historical) | School | 220 | Defiance | 41 16 55 N | 084 36 41 W |
| Shady Glen | Populated Place | 318 | Jefferson | 40 28 48 N | 080 38 23 W |
| Shady Glen Church | Church | 212 | Ross | 39 16 04 N | 083 07 03 W |
| Shady Grove | Populated Place | 335 | Fayette | 39 42 12 N | 083 38 32 W |
| Shady Grove Baptist Church of Christ | Church | 243 | Franklin | 39 58 04 N | 082 58 30 W |