Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Eaton Breaker | Building | 282 | Lackawanna | 41 30 02 N | 075 32 27 W |
| Eaton Colliery (historical) | Building | 336 | Lackawanna | 41 30 02 N | 075 34 02 W |
| Ebenezer Maxwell House | Building | 83 | Philadelphia | 40 02 18 N | 075 11 00 W |
| Eddington Station | Building | 15 | Bucks | 40 05 00 N | 074 56 02 W |
| Eddy Creek Shaft Breaker | Building | 244 | Lackawanna | 41 27 46 N | 075 36 41 W |
| Edwin Forrest Home | Building | 71 | Philadelphia | 39 59 35 N | 075 13 10 W |
| Eilzabethtown Borough Wastewater Treatment Plant | Building | 119 | Lancaster | 40 07 47 N | 076 37 30 W |
| Elk Creek Breaker | Building | 367 | Lackawanna | 41 35 58 N | 075 29 05 W |
| Elk Haven County Home | Building | 531 | Elk | 41 27 16 N | 078 33 12 W |
| Elkland Boro Courthouse | Building | 343 | Tioga | 41 59 14 N | 077 18 37 W |
| Elkland Boro Fire Station | Building | 344 | Tioga | 41 59 14 N | 077 18 49 W |
| Elkland Boro Police Department | Building | 344 | Tioga | 41 59 14 N | 077 18 49 W |
| Elkland Library | Building | 346 | Tioga | 41 59 31 N | 077 18 39 W |
| Elwin Station | Building | 60 | Delaware | 39 54 37 N | 075 24 33 W |
| End Bailys Run Branch Station | Building | 241 | Allegheny | 40 35 32 N | 079 46 40 W |
| Endeavor Community Center | Building | 338 | Forest | 41 35 21 N | 079 23 06 W |
| Ennis Hall | Building | 403 | Westmoreland | 40 19 03 N | 079 33 36 W |
| Erie Breaker | Building | 302 | Lackawanna | 41 32 48 N | 075 31 34 W |
| Erie Station | Building | 34 | Philadelphia | 40 00 26 N | 075 08 09 W |
| Ewin Breaker (historical) | Building | 202 | Luzerne | 41 18 30 N | 075 48 35 W |
| Exeter Friends Meeting House | Building | 75 | Berks | 40 18 47 N | 075 47 03 W |
| Expedit PO (historical) | Building | 504 | Cambria | 40 29 48 N | 078 51 57 W |
| Fair Acres Geriatric Center | Building | 107 | Delaware | 39 55 02 N | 075 26 48 W |
| Fairmount Waterworks | Building | 6 | Philadelphia | 39 57 57 N | 075 11 01 W |
| Falling Waters Museum | Building | 420 | Fayette | 39 54 18 N | 079 27 59 W |
| Farm and Home Center | Building | 104 | Lancaster | 40 04 11 N | 076 19 33 W |
| Faudie Grange | Building | 522 | Clearfield | 41 00 33 N | 078 43 43 W |
| Fayette County Home | Building | 363 | Fayette | 39 54 44 N | 079 45 03 W |
| Fels Planetarium | Building | 7 | Philadelphia | 39 57 27 N | 075 10 21 W |
| Fern Rock Station | Building | 50 | Philadelphia | 40 02 42 N | 075 08 05 W |
| Fernwood Station | Building | 33 | Delaware | 39 56 22 N | 075 15 24 W |
| Fireman Recreation Hall | Building | 300 | Westmoreland | 40 37 51 N | 079 37 21 W |
| Firemans Hall Museum | Building | 7 | Philadelphia | 39 57 12 N | 075 08 39 W |
| First Bank of the United States | Building | 6 | Philadelphia | 39 56 51 N | 075 08 48 W |
| Fitzgerald Fieldhouse | Building | 340 | Allegheny | 40 26 39 N | 079 57 56 W |
| Foley Station (historical) | Building | 465 | Somerset | 39 49 48 N | 078 49 17 W |
| Fonthill Museum | Building | 130 | Bucks | 40 19 16 N | 075 07 21 W |
| Forest City Breaker | Building | 450 | Susquehanna | 41 38 52 N | 075 27 51 W |
| Forest County Courthouse | Building | 333 | Forest | 41 29 47 N | 079 27 20 W |
| Forest County Jail | Building | 335 | Forest | 41 29 47 N | 079 27 19 W |
| Fort Hunter Museum | Building | 97 | Dauphin | 40 20 34 N | 076 54 38 W |
| Fort Perry Station | Building | 231 | Allegheny | 40 23 53 N | 079 48 54 W |
| Fort Pitt Block House | Building | 223 | Allegheny | 40 26 28 N | 080 00 35 W |
| Fort Pitt Museum | Building | 222 | Allegheny | 40 26 29 N | 080 00 36 W |
| Fortney P O (historical) | Building | 206 | York | 40 05 53 N | 076 54 25 W |
| Foster Station | Building | 307 | Susquehanna | 41 42 12 N | 075 45 45 W |
| Foster Township Municipal Building | Building | 435 | McKean | 41 59 22 N | 078 37 04 W |
| Founders Hall | Building | 130 | Dauphin | 40 16 16 N | 076 37 32 W |
| Frankford Station | Building | 6 | Philadelphia | 40 00 24 N | 075 05 05 W |
| Franklin Center | Building | 88 | Delaware | 39 54 20 N | 075 27 08 W |
| Franklin Court | Building | 7 | Philadelphia | 39 56 58 N | 075 08 49 W |
| Franklin Institute Research Lab | Building | 8 | Philadelphia | 39 57 25 N | 075 10 21 W |
| Franklin Print Shop | Building | 8 | Philadelphia | 39 57 02 N | 075 08 50 W |
| Freeport Junction Station (historical) | Building | 250 | Armstrong | 40 40 33 N | 079 40 38 W |
| Fresh Air Home | Building | 356 | Allegheny | 40 40 22 N | 080 04 56 W |
| Friendship Country Home | Building | 70 | Berks | 40 18 44 N | 075 50 59 W |
| Fruit Research Labratory of Penn State | Building | 200 | Adams | 39 55 51 N | 077 14 56 W |
| Fulton Opera House | Building | 109 | Lancaster | 40 02 26 N | 076 18 27 W |
| Gateway Center | Building | 221 | Allegheny | 40 26 33 N | 080 00 21 W |
| Gateway Center Station | Building | 222 | Allegheny | 40 26 33 N | 080 00 27 W |
| Glanford Station | Building | 248 | Allegheny | 40 27 33 N | 080 02 57 W |
| Glanside Station | Building | 77 | Montgomery | 40 06 03 N | 075 09 14 W |
| Glen Olden Station | Building | 25 | Delaware | 39 53 48 N | 075 17 23 W |
| Glenwood Station | Building | 231 | Allegheny | 40 24 11 N | 079 56 41 W |
| Governors Mansion | Building | 93 | Dauphin | 40 16 39 N | 076 53 56 W |
| Gowen Colliery | Building | 326 | Luzerne | 40 56 46 N | 076 10 53 W |
| Gracedale County Home | Building | 147 | Northampton | 40 44 22 N | 075 20 13 W |
| Graff House | Building | 11 | Philadelphia | 39 57 03 N | 075 09 09 W |
| Grassy Island Breaker | Building | 253 | Lackawanna | 41 28 25 N | 075 35 19 W |
| Green Point Fire Company | Building | 157 | Lebanon | 40 28 43 N | 076 33 33 W |
| Green Ridge Breaker | Building | 227 | Lackawanna | 41 25 07 N | 075 39 08 W |
| Green Ridge Station | Building | 224 | Lackawanna | 41 25 42 N | 075 39 14 W |
| Greene County Home (historical) | Building | 314 | Greene | 39 53 20 N | 080 07 28 W |
| Greene County Museum | Building | 314 | Greene | 39 53 21 N | 080 07 28 W |
| Greenock Station | Building | 228 | Allegheny | 40 18 49 N | 079 47 31 W |
| Greenwood Mausoleum | Building | 453 | Lackawanna | 41 27 53 N | 075 41 41 W |
| Gregg Township Office | Building | 197 | Union | 41 07 58 N | 076 59 29 W |
| Guyastuta Station | Building | 226 | Allegheny | 40 29 18 N | 079 54 05 W |
| Hall P O (historical) | Building | 143 | York | 40 01 10 N | 076 58 51 W |
| Hall Station | Building | 263 | Allegheny | 40 26 08 N | 079 48 12 W |
| Hallam Station | Building | 104 | York | 39 59 56 N | 076 36 14 W |
| Han Herr House | Building | 146 | Lancaster | 39 58 26 N | 076 15 47 W |
| Harbor Creek Youth Services | Building | 294 | Erie | 42 06 16 N | 080 01 16 W |
| Harmarville Rehabilitation Center | Building | 368 | Allegheny | 40 32 58 N | 079 52 14 W |
| Harmony Township Community Center | Building | 331 | Forest | 41 34 01 N | 079 24 34 W |
| Harrison Manns Choice Community Center | Building | 350 | Bedford | 40 00 17 N | 078 35 35 W |
| Haverford Station | Building | 90 | Montgomery | 40 00 48 N | 075 17 32 W |
| Haycock Township Municipal Building | Building | 169 | Bucks | 40 28 46 N | 075 14 56 W |
| Hays Station | Building | 225 | Allegheny | 40 23 42 N | 079 56 17 W |
| Hazelwood Station | Building | 231 | Allegheny | 40 25 14 N | 079 57 02 W |
| Hazlett Theater | Building | 236 | Allegheny | 40 27 18 N | 080 00 17 W |
| Head House Square | Building | 6 | Philadelphia | 39 56 33 N | 075 08 44 W |
| Heaton Station | Building | 80 | Montgomery | 40 09 15 N | 075 06 26 W |
| Heinz Hall | Building | 222 | Allegheny | 40 26 33 N | 080 00 06 W |
| Henderson Station (historical) | Building | 49 | Montgomery | 40 05 12 N | 075 21 26 W |
| Hershey Information Center | Building | 116 | Dauphin | 40 17 18 N | 076 39 41 W |
| Hershey Museum of American Life | Building | 117 | Dauphin | 40 17 17 N | 076 39 25 W |
| Highland Fling Tavern | Building | 775 | Cambria | 40 35 24 N | 078 26 55 W |
| Hill-Physick-Keith House | Building | 10 | Philadelphia | 39 56 39 N | 075 09 26 W |
| Historical Society of Pennsylvaina | Building | 12 | Philadelphia | 39 56 51 N | 075 09 47 W |
| Hoffman Orphanage | Building | 171 | Adams | 39 44 55 N | 077 10 44 W |
| Holmesburg Prison | Building | 9 | Philadelphia | 40 02 12 N | 075 01 11 W |
| Holy Family Convent | Building | 172 | Montour | 40 58 04 N | 076 37 16 W |
| Home for the Aged | Building | 403 | Butler | 40 52 56 N | 079 43 19 W |
| Home of John Audubon | Building | 30 | Montgomery | 40 07 24 N | 075 26 41 W |
| Homestead Transfer Station | Building | 231 | Allegheny | 40 24 10 N | 079 55 07 W |
| Honey Brook Colliery (historical) | Building | 521 | Schuylkill | 40 54 58 N | 076 00 17 W |
| House of Good Shepherd | Building | 80 | Berks | 40 21 11 N | 075 56 36 W |
| Humboldt Colliery | Building | 532 | Luzerne | 40 56 11 N | 076 02 23 W |
| Huntingdon Valley Station | Building | 37 | Montgomery | 40 07 15 N | 075 04 23 W |