Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Saint Phillips Church | Church | 124 | Lee | 34 06 18 N | 080 25 32 W |
| Saint Phillips Church | Church | 105 | Lee | 34 14 20 N | 080 25 00 W |
| Saint Phillips School (historical) | School | 93 | Lee | 34 14 24 N | 080 24 44 W |
| Saint Sinai Church | Church | 50 | Lee | 34 02 44 N | 080 12 59 W |
| Saints Church | Church | 83 | Lee | 34 11 29 N | 080 22 41 W |
| Salem Church | Church | 94 | Lee | 34 11 41 N | 080 22 58 W |
| Sand Hill Cemetery | Cemetery | 88 | Lee | 34 07 43 N | 080 27 04 W |
| Sanders Bridge (historical) | Bridge | 38 | Lee | 34 05 09 N | 080 04 20 W |
| Sanders Cemetery | Cemetery | 45 | Lee | 34 04 59 N | 080 05 31 W |
| Sandy Bluff School (historical) | School | 71 | Lee | 34 16 19 N | 080 11 48 W |
| Sandy Grove Church | Church | 55 | Lee | 34 11 13 N | 080 08 33 W |
| Savannah Cemetery | Cemetery | 66 | Lee | 34 18 24 N | 080 12 04 W |
| Savannah Church | Church | 65 | Lee | 34 18 25 N | 080 12 06 W |
| Scotts Cemetery | Cemetery | 55 | Lee | 34 08 56 N | 080 13 02 W |
| Scottville School (historical) | School | 40 | Lee | 33 57 33 N | 080 09 55 W |
| Shady Grove Church | Church | 72 | Lee | 34 16 17 N | 080 11 46 W |
| Shannon Hill | Populated Place | 47 | Lee | 34 15 06 N | 080 12 14 W |
| Shannon Hill Church | Church | 60 | Lee | 34 15 08 N | 080 12 02 W |
| Shaws Mission School (historical) | School | 103 | Lee | 34 15 42 N | 080 18 24 W |
| Shaws Pond | Reservoir | 54 | Lee | 34 08 37 N | 080 14 29 W |
| Shekinah Tabernacle | Church | 69 | Lee | 34 13 14 N | 080 15 03 W |
| Shiver Millpond | Lake | 66 | Lee | 34 10 31 N | 080 27 44 W |
| Shrocks Mill School (historical) | School | 96 | Lee | 34 17 05 N | 080 24 25 W |
| Singletary Millpond | Reservoir | 61 | Lee | 34 14 37 N | 080 21 17 W |
| Singletary Millpond Dam D-2410 | Dam | 67 | Lee | 34 14 42 N | 080 21 16 W |
| Smith Pond | Reservoir | 59 | Lee | 34 17 43 N | 080 09 11 W |
| South Carolina Noname 31001 D-2425 Dam | Dam | 59 | Lee | 34 17 43 N | 080 09 11 W |
| South Carolina Noname 31003 D-2424 Dam | Dam | 44 | Lee | 34 01 37 N | 080 11 47 W |
| South Carolina Noname 31004 D-2423 Dam | Dam | 46 | Lee | 34 01 13 N | 080 11 53 W |
| South Carolina Noname 31006 D-2418 Dam | Dam | 54 | Lee | 34 08 37 N | 080 14 29 W |
| South Carolina Noname 31007 D-2419 Dam | Dam | 58 | Lee | 34 18 49 N | 080 15 05 W |
| South Carolina Noname 31009 D-2412 Dam | Dam | 70 | Lee | 34 19 49 N | 080 18 11 W |
| South Carolina Noname 31012 D-2414 Dam | Dam | 53 | Lee | 34 06 06 N | 080 18 57 W |
| South Carolina Noname 31013 D-2407 Dam | Dam | 62 | Lee | 34 08 05 N | 080 20 19 W |
| South Carolina Noname 31014 D-2411 Dam | Dam | 65 | Lee | 34 13 31 N | 080 20 59 W |
| South Carolina Noname 31015 D-2413 Dam | Dam | 70 | Lee | 34 16 42 N | 080 22 15 W |
| South Carolina Noname 31016 D-2406 Dam | Dam | 69 | Lee | 34 08 37 N | 080 22 35 W |
| South Carolina Noname 31018 D-2408 Dam | Dam | 75 | Lee | 34 11 47 N | 080 24 27 W |
| South Carolina Noname 31019 D-2415 Dam | Dam | 67 | Lee | 34 12 43 N | 080 16 59 W |
| South Carolina Noname 31021 D-2420 Dam | Dam | 54 | Lee | 34 11 01 N | 080 14 05 W |
| South Carolina Noname 31022 D-2421 Dam | Dam | 52 | Lee | 34 13 43 N | 080 12 59 W |
| South Lynchburg | Populated Place | 46 | Lee | 34 03 09 N | 080 03 39 W |
| South Main Historic District | Park | 70 | Lee | 34 12 55 N | 080 15 10 W |
| Spiveys Ferry (historical) | Crossing | 58 | Lee | 34 19 29 N | 080 14 34 W |
| Spring Hill | Populated Place | 106 | Lee | 34 09 06 N | 080 26 18 W |
| Spring Hill | Summit | 149 | Lee | 34 08 43 N | 080 25 55 W |
| Spring Hill School (historical) | School | 107 | Lee | 34 09 06 N | 080 26 17 W |
| Spur | Populated Place | 73 | Lee | 34 10 06 N | 080 17 53 W |
| Stokes Bridge | Locale | 69 | Lee | 34 17 45 N | 080 12 16 W |
| Stokes Bridge (historical) | Bridge | 48 | Lee | 34 20 32 N | 080 15 18 W |
| Stony Run Branch | Stream | | Lee | 34 03 13 N | 080 10 53 W |
| Sunesac Lake | Reservoir | 65 | Lee | 34 18 31 N | 080 16 05 W |
| Sunesac Lake Dam D-2417 | Dam | 65 | Lee | 34 18 31 N | 080 16 05 W |
| Tallon Field | Airport | 50 | Lee | 34 06 04 N | 080 07 32 W |
| Thomastown School (historical) | School | 83 | Lee | 34 12 24 N | 080 19 04 W |
| Thursa | Populated Place | 97 | Lee | 34 15 17 N | 080 17 14 W |
| Turkey Creek | Stream | | Lee | 34 18 51 N | 080 14 24 W |
| Turkey Creek Cemetery | Cemetery | 75 | Lee | 34 19 53 N | 080 17 41 W |
| Turkey Creek Church (historical) | Church | 78 | Lee | 34 20 01 N | 080 18 27 W |
| Turkey Creek Presbyterian Church (historical) | Church | 75 | Lee | 34 19 53 N | 080 17 39 W |
| Turkey Creek School (historical) | School | 74 | Lee | 34 19 29 N | 080 17 14 W |
| Turkey Creek School (historical) | School | 80 | Lee | 34 20 01 N | 080 18 17 W |
| Turners Pond | Reservoir | 44 | Lee | 34 01 37 N | 080 11 47 W |
| Unionville Church | Church | 52 | Lee | 34 03 44 N | 080 14 47 W |
| WAGS-AM (Bishopville) | Tower | 64 | Lee | 34 12 37 N | 080 13 49 W |
| Watsons Mill (historical) | Locale | 63 | Lee | 34 16 16 N | 080 15 24 W |
| Wayside Church | Church | 61 | Lee | 34 14 03 N | 080 11 37 W |
| Weatherly (historical) | Populated Place | 66 | Lee | 34 14 35 N | 080 11 45 W |
| Wells Cemetery | Cemetery | 49 | Lee | 34 04 02 N | 080 09 52 W |
| Wells Church (historical) | Church | 47 | Lee | 34 04 03 N | 080 09 54 W |
| Wells Crossroads | Populated Place | 48 | Lee | 34 04 05 N | 080 09 45 W |
| Wesley Memorial Church | Church | 62 | Lee | 34 12 45 N | 080 14 58 W |
| West Lee School | School | 115 | Lee | 34 09 48 N | 080 25 12 W |
| Whilden Cemetery | Cemetery | 70 | Lee | 34 09 02 N | 080 19 26 W |
| Windi Knoll Lake | Reservoir | 79 | Lee | 34 13 37 N | 080 24 11 W |
| Windi Knoll Lake D-1723 Dam | Dam | 79 | Lee | 34 13 37 N | 080 24 11 W |
| Wisacky | Populated Place | 62 | Lee | 34 08 54 N | 080 11 36 W |
| Witherspoon School | School | 42 | Lee | 33 58 40 N | 080 09 15 W |
| Woodrow | Populated Place | 74 | Lee | 34 05 42 N | 080 22 40 W |
| Woodrow School (historical) | School | 66 | Lee | 34 05 56 N | 080 22 22 W |
| Woodward Park | Park | 68 | Lee | 34 13 05 N | 080 14 53 W |
| WQHB-TV (Sumter) | Tower | 92 | Lee | 34 08 54 N | 080 28 12 W |
| WXMA-FM (Bishopville) | Tower | 105 | Lee | 34 16 27 N | 080 20 12 W |
| Zemp | Populated Place | 106 | Lee | 34 16 15 N | 080 19 36 W |
| Abells Mill (historical) | Locale | 128 | Lexington | 33 52 15 N | 081 27 32 W |
| Abells Millpond | Reservoir | 128 | Lexington | 33 52 13 N | 081 27 31 W |
| Acapulco | Populated Place | 126 | Lexington | 34 03 52 N | 081 28 22 W |
| Air South Industrial Park | Locale | 88 | Lexington | 33 55 16 N | 081 04 41 W |
| Airport Church | Church | 97 | Lexington | 33 57 55 N | 081 07 55 W |
| Airport High School | School | 69 | Lexington | 33 57 03 N | 081 06 16 W |
| Althea (historical) | Populated Place | 110 | Lexington | 33 48 45 N | 081 27 49 W |
| Altman Pond | Lake | 103 | Lexington | 33 44 42 N | 081 23 42 W |
| American Creative School | School | 90 | Lexington | 33 59 02 N | 081 04 31 W |
| Amicks Ferry (historical) | Crossing | 110 | Lexington | 34 04 58 N | 081 25 28 W |
| Ansel Smith Pond | Reservoir | 143 | Lexington | 33 52 55 N | 081 28 35 W |
| Antioch Cemetery | Cemetery | 141 | Lexington | 33 45 46 N | 081 09 48 W |
| Antioch Church | Church | 145 | Lexington | 33 45 47 N | 081 09 54 W |
| Apollo Gardens (subdivision) | Populated Place | 70 | Lexington | 33 54 31 N | 081 06 38 W |
| Arborgate (subdivision) | Populated Place | 67 | Lexington | 33 54 54 N | 081 05 53 W |
| Areharts Pond Dam D-1716 | Dam | 112 | Lexington | 33 45 01 N | 081 20 59 W |
| Armour Pond | Reservoir | 56 | Lexington | 33 54 31 N | 081 08 44 W |
| Arrants Pond | Reservoir | 89 | Lexington | 33 55 25 N | 081 14 05 W |
| Arthur | Populated Place | 96 | Lexington | 33 58 19 N | 081 08 15 W |
| Arthur Fire Tower (historical) | Tower | 137 | Lexington | 33 58 07 N | 081 10 23 W |
| Assembly of God Church | Church | 125 | Lexington | 33 56 42 N | 081 14 11 W |
| Athens Church | Church | 146 | Lexington | 33 47 06 N | 081 05 59 W |
| Athens School (historical) | School | 146 | Lexington | 33 47 05 N | 081 05 58 W |
| Athens School (historical) | School | 132 | Lexington | 33 46 25 N | 081 05 55 W |
| Augusta Street Presbyterian Church | Church | 64 | Lexington | 33 59 26 N | 081 03 37 W |
| Bachman Cemetery | Cemetery | 137 | Lexington | 33 45 13 N | 081 09 27 W |