Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Carver Elementary School | School | 44 | Florence | 34 12 12 N | 079 47 05 W |
| Cash | Populated Place | 44 | Chesterfield | 34 37 07 N | 079 52 38 W |
| Cash Baptist Church | Church | 44 | Chesterfield | 34 36 33 N | 079 52 37 W |
| Cattle Creek Campground | Locale | 44 | Orangeburg | 33 19 20 N | 080 45 03 W |
| Cattle Creek Cemetery | Cemetery | 44 | Orangeburg | 33 19 22 N | 080 45 03 W |
| Center School (historical) | School | 44 | Orangeburg | 33 22 39 N | 080 37 07 W |
| Church of God (historical) | Church | 44 | Florence | 34 07 46 N | 079 56 49 W |
| Church of Jesus (historical) | Church | 44 | Florence | 34 12 24 N | 079 45 56 W |
| Clayton School (historical) | School | 44 | Richland | 33 51 40 N | 080 51 38 W |
| Clear Pond | Populated Place | 44 | Bamberg | 33 11 18 N | 081 01 44 W |
| Clearwater Lake | Reservoir | 44 | Aiken | 33 30 21 N | 081 53 39 W |
| Clearwater Lake Dam | Dam | 44 | Aiken | 33 30 21 N | 081 53 39 W |
| Coggins Grove Church (historical) | Church | 44 | Bamberg | 33 07 60 N | 081 02 57 W |
| Coggins School (historical) | School | 44 | Bamberg | 33 06 39 N | 081 02 16 W |
| Collier School | School | 44 | Orangeburg | 33 18 07 N | 080 50 05 W |
| Cones Store (historical) | Locale | 44 | Allendale | 33 01 26 N | 081 10 34 W |
| Covington Mill (historical) | Locale | 44 | Marlboro | 34 36 26 N | 079 37 49 W |
| Curtis Millpond | Reservoir | 44 | Clarendon | 33 43 37 N | 080 23 34 W |
| Damascus Number 2 Church | Church | 44 | Richland | 33 51 39 N | 080 51 36 W |
| Dewitt Pond Dam D-3555 | Dam | 44 | Darlington | 34 12 19 N | 079 53 17 W |
| Dundee Acres (subdivision) | Populated Place | 44 | Marlboro | 34 36 15 N | 079 42 30 W |
| East Florence Church | Church | 44 | Florence | 34 11 57 N | 079 44 19 W |
| East Sumter | Populated Place | 44 | Sumter | 33 55 32 N | 080 17 46 W |
| Ehrhardt | Populated Place | 44 | Bamberg | 33 05 49 N | 081 00 51 W |
| Ehrhardt Airport | Airport | 44 | Bamberg | 33 05 23 N | 081 00 29 W |
| Ehrhardt Post Office | Post Office | 44 | Bamberg | 33 05 49 N | 081 00 49 W |
| Ehrhardt United Methodist Church | Church | 44 | Bamberg | 33 05 32 N | 081 00 49 W |
| Emanuel Cemetery | Cemetery | 44 | Orangeburg | 33 19 25 N | 080 55 46 W |
| Emanuel Church | Church | 44 | Orangeburg | 33 19 26 N | 080 55 49 W |
| Enon School (historical) | School | 44 | Florence | 34 07 56 N | 079 58 39 W |
| Evergreen Cemetery | Cemetery | 44 | Dillon | 34 27 34 N | 079 20 04 W |
| Faith Church | Church | 44 | Florence | 34 12 46 N | 079 51 41 W |
| Felderville Church | Church | 44 | Orangeburg | 33 26 29 N | 080 36 53 W |
| Ferndale | Populated Place | 44 | Florence | 34 11 24 N | 079 54 13 W |
| First Assembly of God Church | Church | 44 | Florence | 34 11 23 N | 079 47 58 W |
| First Baptist Church | Church | 44 | Florence | 34 08 07 N | 079 56 39 W |
| First Church of the Nazarene | Church | 44 | Florence | 34 11 33 N | 079 47 41 W |
| Fish Hatchery Lake One Dam D-3222 | Dam | 44 | Chesterfield | 34 37 37 N | 079 56 23 W |
| Fishers Hill School (historical) | School | 44 | Chesterfield | 34 40 19 N | 079 56 15 W |
| Five Forks | Populated Place | 44 | Dillon | 34 28 46 N | 079 19 16 W |
| Florence County Courthouse | Building | 44 | Florence | 34 11 54 N | 079 46 03 W |
| Florence County Jail | Building | 44 | Florence | 34 11 54 N | 079 46 02 W |
| Florence Post Office | Post Office | 44 | Florence | 34 11 52 N | 079 46 06 W |
| Florence Public Library | Building | 44 | Florence | 34 11 32 N | 079 46 05 W |
| Fox Tindal Pond | Reservoir | 44 | Clarendon | 33 39 13 N | 080 26 35 W |
| Glad Tidings Church | Church | 44 | Florence | 34 08 49 N | 079 53 13 W |
| Golden Acre Mobile Home Park | Populated Place | 44 | Sumter | 33 55 31 N | 080 18 23 W |
| Goodland Church | Church | 44 | Bamberg | 33 12 01 N | 080 55 27 W |
| Hamer | Populated Place | 44 | Dillon | 34 28 41 N | 079 19 51 W |
| Harllee Natural History Museum | Building | 44 | Florence | 34 11 32 N | 079 47 22 W |
| Hendricks Pond Dam D-3230 | Dam | 44 | Chesterfield | 34 36 25 N | 079 54 47 W |
| High Hill Church | Church | 44 | Darlington | 34 14 09 N | 079 53 26 W |
| Home Branch School (historical) | School | 44 | Clarendon | 33 45 24 N | 080 18 40 W |
| Hunters Chapel School (historical) | School | 44 | Bamberg | 33 10 38 N | 080 55 14 W |
| Iola Jones Park | Park | 44 | Florence | 34 12 25 N | 079 45 27 W |
| Island Cemeteries | Cemetery | 44 | Orangeburg | 33 25 34 N | 080 34 20 W |
| Islay (historical) | Populated Place | 44 | Marlboro | 34 37 27 N | 079 43 38 W |
| Jehovah Church of Christ | Church | 44 | Florence | 34 08 06 N | 079 56 37 W |
| Jerusalem Church | Church | 44 | Orangeburg | 33 30 36 N | 080 32 42 W |
| Jessie Rast Pond | Reservoir | 44 | Calhoun | 33 33 25 N | 080 41 05 W |
| Jessie Rast Pond Dam D-2687 | Dam | 44 | Calhoun | 33 33 25 N | 080 41 05 W |
| Kelly Farms | Populated Place | 44 | Florence | 34 10 30 N | 079 54 29 W |
| Lake Katherine | Reservoir | 44 | Richland | 34 00 11 N | 080 57 50 W |
| Lake Katherine Dam | Dam | 44 | Richland | 34 00 11 N | 080 57 50 W |
| Lake Wallace | Reservoir | 44 | Marlboro | 34 37 50 N | 079 40 52 W |
| Liberty Heights (subdivision) | Populated Place | 44 | Darlington | 34 19 23 N | 079 51 50 W |
| Linkside | Populated Place | 44 | Dillon | 34 27 39 N | 079 19 27 W |
| Macedonia Church | Church | 44 | Bamberg | 33 09 10 N | 081 04 21 W |
| Marlboro County Airport | Airport | 44 | Marlboro | 34 37 21 N | 079 44 05 W |
| Mattie Js Pond | Reservoir | 44 | Lee | 34 04 48 N | 080 12 09 W |
| Mattie Js Pond Dam D-2422 | Dam | 44 | Lee | 34 04 48 N | 080 12 09 W |
| Maxwell Baptist Church | Church | 44 | Florence | 34 12 33 N | 079 44 55 W |
| McCayhan Cemetery | Cemetery | 44 | Dillon | 34 28 48 N | 079 20 35 W |
| McIntosh Millpond | Reservoir | 44 | Darlington | 34 24 56 N | 079 59 24 W |
| McKenzie School | School | 44 | Florence | 34 11 43 N | 079 46 35 W |
| McLaurin Pond | Reservoir | 44 | Sumter | 33 50 31 N | 080 20 23 W |
| McLaurin Pond Dam D-2062 | Dam | 44 | Sumter | 33 50 31 N | 080 20 23 W |
| Midland Acres | Populated Place | 44 | Sumter | 33 55 32 N | 080 17 24 W |
| Mill Branch School | School | 44 | Orangeburg | 33 19 14 N | 080 49 37 W |
| Mill Creek Park Pond | Reservoir | 44 | Sumter | 33 44 07 N | 080 31 29 W |
| Mill Creek Pond Park Dam D-2066 | Dam | 44 | Sumter | 33 44 07 N | 080 31 29 W |
| Mount Carmel Baptist Church (historical) | Church | 44 | Florence | 34 12 11 N | 079 46 13 W |
| Mount Olive Church | Church | 44 | Orangeburg | 33 18 60 N | 080 43 37 W |
| Mount Zion United Methodist Church | Church | 44 | Florence | 34 08 11 N | 079 56 31 W |
| Mulberry Picnic Pond | Reservoir | 44 | Kershaw | 34 11 49 N | 080 33 47 W |
| Mulberry Picnic Pond Dam D-2506 | Dam | 44 | Kershaw | 34 11 49 N | 080 33 47 W |
| Mulberry School (historical) | School | 44 | Sumter | 33 49 43 N | 080 17 29 W |
| Murray Lake | Reservoir | 44 | Richland | 33 59 07 N | 080 42 29 W |
| New Holy Church | Church | 44 | Dillon | 34 33 04 N | 079 27 15 W |
| New Holy School (historical) | School | 44 | Dillon | 34 33 06 N | 079 27 09 W |
| North Vista Cemetery | Cemetery | 44 | Florence | 34 12 33 N | 079 45 36 W |
| Northwest Community Park | Park | 44 | Florence | 34 12 29 N | 079 46 54 W |
| Northwest Junction (historical) | Locale | 44 | Kershaw | 34 11 46 N | 080 34 57 W |
| Oak Grove | Populated Place | 44 | Dillon | 34 21 06 N | 079 32 33 W |
| Oak Grove School | School | 44 | Bamberg | 33 08 06 N | 080 58 13 W |
| Oak Grove School (historical) | School | 44 | Dillon | 34 21 10 N | 079 32 36 W |
| Peaceful Baptist Church | Church | 44 | Florence | 34 12 11 N | 079 46 13 W |
| Peedee Agricultural Experiment Station | Locale | 44 | Florence | 34 12 56 N | 079 47 06 W |
| Peeples (historical) | Populated Place | 44 | Hampton | 32 47 28 N | 081 18 47 W |
| Pentecostal Holiness Church | Church | 44 | Florence | 34 12 02 N | 079 46 08 W |
| Pepper Ridge (subdivision) | Populated Place | 44 | Darlington | 34 17 26 N | 079 50 45 W |
| Pilgrim Church | Church | 44 | Bamberg | 33 17 12 N | 080 58 48 W |
| Pine Acres | Populated Place | 44 | Darlington | 34 12 41 N | 079 52 31 W |
| Pleasant Hill Church (historical) | Church | 44 | Bamberg | 33 09 48 N | 081 00 48 W |
| Pleasant View (historical) | Populated Place | 44 | Florence | 34 07 17 N | 079 57 56 W |
| Pocalla Springs | Populated Place | 44 | Sumter | 33 52 19 N | 080 21 15 W |
| Prospect School (historical) | School | 44 | Orangeburg | 33 20 37 N | 080 45 24 W |
| Red Hill Church | Church | 44 | Richland | 33 51 26 N | 080 44 53 W |
| Red Hill Church (historical) | Church | 44 | Richland | 33 51 37 N | 080 45 10 W |
| Red Hill School (historical) | School | 44 | Richland | 33 51 22 N | 080 44 50 W |