Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Sandy Island Bridge | Bridge | 32 | Bamberg | 33 10 42 N | 080 48 06 W |
| Skinface Pond | Reservoir | 32 | Aiken | 33 14 18 N | 081 46 39 W |
| Smith Store (historical) | Locale | 32 | Hampton | 32 44 08 N | 081 08 19 W |
| Smoaks | Populated Place | 32 | Colleton | 33 05 23 N | 080 48 50 W |
| South Carolina Noname 09001 D-2614 Dam | Dam | 32 | Calhoun | 33 47 13 N | 080 01 47 W |
| South Carolina Noname 09031 D-2645 Dam | Dam | 32 | Calhoun | 33 35 01 N | 080 35 47 W |
| South Carolina Noname 35015 Dam D-3427 | Dam | 32 | Marlboro | 34 45 19 N | 079 52 59 W |
| South Carolina Noname 38020 D-3762 Dam | Dam | 32 | Orangeburg | 33 27 31 N | 080 26 29 W |
| Sparrow Swamp Cemetery | Cemetery | 32 | Florence | 34 03 16 N | 079 52 37 W |
| Sparrow Swamp Church | Church | 32 | Florence | 34 03 13 N | 079 52 34 W |
| Sparrows Crossroads | Populated Place | 32 | Florence | 34 03 15 N | 079 52 47 W |
| Spring Branch Church | Church | 32 | Horry | 34 15 33 N | 079 02 06 W |
| Spring Branch School | School | 32 | Marion | 34 14 36 N | 079 24 01 W |
| Spring Branch School (historical) | School | 32 | Horry | 34 15 32 N | 079 02 02 W |
| Spring Grove Church | Church | 32 | Dillon | 34 17 51 N | 079 21 27 W |
| Squires Lake Dam D-0851 | Dam | 32 | Dillon | 34 25 07 N | 079 21 17 W |
| Stafford | Populated Place | 32 | Hampton | 32 40 13 N | 081 09 53 W |
| Strickland Cemetery | Cemetery | 32 | Horry | 34 12 24 N | 078 59 33 W |
| Thompson School (historical) | School | 32 | Hampton | 32 46 34 N | 081 20 06 W |
| Timrod Park | Park | 32 | Florence | 34 11 06 N | 079 46 20 W |
| Trinity Cemetery | Cemetery | 32 | Allendale | 32 52 27 N | 081 24 20 W |
| Trinity Cemetery | Cemetery | 32 | Colleton | 33 05 33 N | 080 48 50 W |
| Trinity Church | Church | 32 | Allendale | 32 52 28 N | 081 24 19 W |
| Trinity Church | Church | 32 | Clarendon | 33 44 28 N | 080 11 16 W |
| Turner Bay | Swamp | 32 | Florence | 34 03 17 N | 079 42 03 W |
| Turner Cemetery | Cemetery | 32 | Marion | 34 17 11 N | 079 24 58 W |
| Tyndall Cemetery | Cemetery | 32 | Dillon | 34 17 40 N | 079 21 36 W |
| Union Church | Church | 32 | Dillon | 34 23 34 N | 079 14 35 W |
| Union Hill Church | Church | 32 | Clarendon | 33 54 14 N | 079 58 44 W |
| Union Hill School | School | 32 | Clarendon | 33 54 13 N | 079 58 45 W |
| Welch Green School (historical) | School | 32 | Colleton | 32 57 43 N | 080 36 17 W |
| Whitestone Cemetery | Cemetery | 32 | Dorchester | 33 09 60 N | 080 40 09 W |
| Whitestone Church | Church | 32 | Dorchester | 33 09 58 N | 080 40 11 W |
| Williams | Populated Place | 32 | Colleton | 33 02 05 N | 080 50 33 W |
| Williamson Park | Park | 32 | Darlington | 34 18 44 N | 079 51 54 W |
| WJBS-AM (Holly Hill) | Tower | 32 | Orangeburg | 33 20 24 N | 080 26 17 W |
| Wren Creek (subdivision) | Populated Place | 32 | Florence | 34 10 51 N | 079 48 32 W |
| Wyboo Church (historical) | Church | 32 | Clarendon | 33 32 21 N | 080 13 02 W |
| Wymans School | School | 32 | Hampton | 32 59 41 N | 081 01 11 W |
| Zion Church (historical) | Church | 32 | Marion | 34 16 24 N | 079 20 08 W |
| Aynor | Populated Place | 31 | Horry | 33 59 60 N | 079 11 58 W |
| Aynor High School | School | 31 | Horry | 33 59 60 N | 079 12 28 W |
| Bayboro | Populated Place | 31 | Horry | 34 00 35 N | 079 01 20 W |
| Beards Crossroads | Populated Place | 31 | Clarendon | 33 51 42 N | 080 02 25 W |
| Berea Church | Church | 31 | Horry | 34 01 44 N | 079 06 00 W |
| Bermuda Church | Church | 31 | Dillon | 34 21 56 N | 079 16 45 W |
| Bermuda High School (historical) | School | 31 | Dillon | 34 21 57 N | 079 16 42 W |
| Bethany Church | Church | 31 | Colleton | 33 01 31 N | 080 32 26 W |
| Bethel Chapel | Church | 31 | Horry | 34 03 20 N | 079 04 32 W |
| Bethel Hill Cemetery | Cemetery | 31 | Dillon | 34 22 28 N | 079 26 49 W |
| Beulah Church | Church | 31 | Florence | 34 10 26 N | 079 42 22 W |
| Biggers Church | Church | 31 | Clarendon | 33 41 29 N | 080 04 27 W |
| Black Creek Church | Church | 31 | Hampton | 32 49 16 N | 081 09 52 W |
| Bowers Chapel | Church | 31 | Florence | 34 12 54 N | 079 36 52 W |
| Brady Pond | Reservoir | 31 | Calhoun | 33 46 13 N | 080 49 53 W |
| Brady Pond Dam D-2624 | Dam | 31 | Calhoun | 33 46 13 N | 080 49 53 W |
| Browns Chapel | Church | 31 | Dorchester | 33 12 05 N | 080 35 32 W |
| Carolina Country Club | Locale | 31 | Horry | 34 05 20 N | 078 50 56 W |
| Carolina School (historical) | School | 31 | Horry | 34 09 32 N | 078 56 12 W |
| Cedar Grove School (historical) | School | 31 | Hampton | 32 56 16 N | 081 06 45 W |
| Central Crossroads | Populated Place | 31 | Clarendon | 33 53 17 N | 079 54 46 W |
| Central School (historical) | School | 31 | Florence | 33 53 19 N | 079 54 42 W |
| Cherry Hill Church | Church | 31 | Horry | 33 59 52 N | 078 53 40 W |
| Clarkes Lake | Lake | 31 | Aiken | 33 20 10 N | 081 53 49 W |
| Clay Hill Cemetery | Cemetery | 31 | Marion | 34 12 34 N | 079 13 16 W |
| Cleland Crossroads | Populated Place | 31 | Hampton | 32 56 21 N | 081 07 04 W |
| Cleland School (historical) | School | 31 | Hampton | 32 56 19 N | 081 06 59 W |
| Colonel Joseph Risher Cemetery | Cemetery | 31 | Colleton | 33 01 56 N | 080 50 01 W |
| Community Church (historical) | Church | 31 | Florence | 33 57 51 N | 079 51 03 W |
| Crutchlow Bay | Swamp | 31 | Dillon | 34 18 10 N | 079 10 24 W |
| Cypress Church | Church | 31 | Clarendon | 33 35 36 N | 080 12 19 W |
| Devils Elbow | Bend | 31 | Richland | 33 45 37 N | 080 41 12 W |
| Dorchester | Populated Place | 31 | Dorchester | 33 08 24 N | 080 23 39 W |
| Dorchester County Courthouse | Building | 31 | Dorchester | 33 11 06 N | 080 34 39 W |
| Dukes | Populated Place | 31 | Hampton | 32 53 52 N | 081 14 16 W |
| Eagle Point | Cape | 31 | Aiken | 33 16 31 N | 081 50 19 W |
| Edisto School | School | 31 | Colleton | 33 08 06 N | 080 44 23 W |
| Elim School (historical) | School | 31 | Florence | 34 02 16 N | 079 49 32 W |
| Evergreen | Populated Place | 31 | Florence | 34 04 07 N | 079 40 44 W |
| Evergreen Baptist Church | Church | 31 | Florence | 34 04 09 N | 079 40 48 W |
| Evergreen Cemetery | Cemetery | 31 | Florence | 34 04 07 N | 079 40 47 W |
| Evergreen Church | Church | 31 | Florence | 34 03 01 N | 079 40 01 W |
| Evergreen School (historical) | School | 31 | Florence | 34 04 08 N | 079 40 38 W |
| Feathery Bay | Swamp | 31 | Horry | 34 11 46 N | 078 58 58 W |
| Fendall | Populated Place | 31 | Florence | 34 08 21 N | 079 41 16 W |
| Flag Patch Church | Church | 31 | Horry | 34 02 41 N | 078 49 11 W |
| Florence County | Civil | 31 | Florence | 34 03 01 N | 079 39 59 W |
| Flowertown Estates (subdivision) | Populated Place | 31 | Dorchester | 33 02 20 N | 080 10 43 W |
| Forest Lake | Reservoir | 31 | Florence | 34 09 31 N | 079 49 41 W |
| Fork School (historical) | School | 31 | Dillon | 34 17 04 N | 079 16 47 W |
| Friendship Church | Church | 31 | Colleton | 33 00 09 N | 081 01 16 W |
| Friendship School | School | 31 | Colleton | 33 00 10 N | 081 01 16 W |
| Friendship School (historical) | School | 31 | Florence | 34 13 15 N | 079 38 19 W |
| Gable School (historical) | School | 31 | Clarendon | 33 49 27 N | 080 06 06 W |
| Gardners Bluff | Cliff | 31 | Marlboro | 34 36 28 N | 079 46 54 W |
| Garners Ferry (historical) | Crossing | 31 | Sumter | 33 56 49 N | 080 37 40 W |
| Garvin Cemetery | Cemetery | 31 | Allendale | 32 53 21 N | 081 25 34 W |
| Glendale Church | Church | 31 | Horry | 34 04 34 N | 078 52 29 W |
| Goodwill Pond | Reservoir | 31 | Richland | 33 57 39 N | 080 39 11 W |
| Goose Pond | Lake | 31 | Richland | 33 50 33 N | 080 54 22 W |
| Green Hill Lake | Lake | 31 | Richland | 33 52 12 N | 080 58 43 W |
| Harris Creek School (historical) | School | 31 | Chesterfield | 34 30 50 N | 079 52 01 W |
| Hayes Cemetery | Cemetery | 31 | Dillon | 34 21 34 N | 079 15 03 W |
| Hayestown Church | Church | 31 | Dillon | 34 21 23 N | 079 15 24 W |
| High Hill School (historical) | School | 31 | Dillon | 34 21 24 N | 079 15 23 W |
| Holly Hill Middle School | School | 31 | Orangeburg | 33 19 31 N | 080 24 58 W |
| Holly Hill Post Office | Post Office | 31 | Orangeburg | 33 19 11 N | 080 24 40 W |
| Holly Hill Primary School | School | 31 | Orangeburg | 33 19 30 N | 080 24 22 W |
| Horse Pond School (historical) | School | 31 | Hampton | 32 44 24 N | 081 08 34 W |
| Howe Cemetery | Cemetery | 31 | Florence | 34 08 21 N | 079 44 40 W |