Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Bryant Temple Church | Church | 27 | Dorchester | 33 04 59 N | 080 27 49 W |
| Buzzard Bay | Swamp | 27 | Berkeley | 33 17 56 N | 080 12 19 W |
| Byrd School | School | 27 | Dorchester | 33 09 52 N | 080 31 03 W |
| Camp Branch | Populated Place | 27 | Florence | 33 54 31 N | 079 49 04 W |
| Camp Branch Cemetery | Cemetery | 27 | Florence | 33 54 32 N | 079 49 01 W |
| Camp Branch Free Will Baptist Church | Church | 27 | Florence | 33 54 30 N | 079 49 01 W |
| Camp Robinson | Locale | 27 | Clarendon | 33 32 06 N | 080 15 41 W |
| Cane Branch Church | Church | 27 | Horry | 34 00 12 N | 078 56 31 W |
| Caney Branch School | School | 27 | Colleton | 32 51 59 N | 080 45 44 W |
| Chinquapin Bay | Swamp | 27 | Berkeley | 33 15 25 N | 080 12 00 W |
| Claussen | Populated Place | 27 | Florence | 34 07 52 N | 079 37 51 W |
| Clemson Terrace (subdivision) | Populated Place | 27 | Dorchester | 33 03 01 N | 080 12 02 W |
| Cobia School (historical) | School | 27 | Clarendon | 33 33 24 N | 080 16 19 W |
| Colleton County Courthouse | Building | 27 | Colleton | 32 54 10 N | 080 40 00 W |
| Corey Point (subdivision) | Populated Place | 27 | Dorchester | 33 00 36 N | 080 12 59 W |
| Coward Post Office | Post Office | 27 | Florence | 33 58 14 N | 079 44 57 W |
| Cross High School | School | 27 | Berkeley | 33 21 06 N | 080 09 49 W |
| Cross School | School | 27 | Berkeley | 33 18 05 N | 080 10 01 W |
| Cypress Lake | Reservoir | 27 | Clarendon | 33 50 55 N | 080 00 17 W |
| Daisy | Populated Place | 27 | Horry | 33 59 44 N | 078 52 02 W |
| Demaries Ferry (historical) | Crossing | 27 | Aiken | 33 12 46 N | 081 48 26 W |
| Ditch Bay | Swamp | 27 | Berkeley | 33 14 13 N | 080 14 04 W |
| Dorchester Academy | School | 27 | Dorchester | 33 11 09 N | 080 33 03 W |
| Douglas Fork Church (historical) | Church | 27 | Clarendon | 33 50 54 N | 079 58 28 W |
| Douglas School (historical) | School | 27 | Clarendon | 33 50 53 N | 079 58 30 W |
| Dukes Cemetery | Cemetery | 27 | Dorchester | 33 10 27 N | 080 35 17 W |
| Dyers Hill Church | Church | 27 | Marlboro | 34 35 03 N | 079 45 47 W |
| Ebenezer Cemetery | Cemetery | 27 | Berkeley | 33 09 07 N | 080 03 34 W |
| Ebenezer Church | Church | 27 | Berkeley | 33 09 06 N | 080 03 35 W |
| Ebenezer School (historical) | School | 27 | Berkeley | 33 09 06 N | 080 03 35 W |
| Effingham Church | Church | 27 | Marion | 34 12 34 N | 079 17 22 W |
| Elam Church | Church | 27 | Dorchester | 33 12 33 N | 080 23 51 W |
| Elbow School (historical) | School | 27 | Colleton | 32 54 03 N | 080 44 11 W |
| Elliot Pond | Reservoir | 27 | Clarendon | 33 39 13 N | 080 29 41 W |
| Elvington Cemetery | Cemetery | 27 | Dillon | 34 19 11 N | 079 12 48 W |
| Fair Haven Church | Church | 27 | Clarendon | 33 42 43 N | 080 09 52 W |
| Fibers Recreation Pond Dam D-3549 | Dam | 27 | Darlington | 34 16 31 N | 079 47 47 W |
| First Baptist Church | Church | 27 | Colleton | 32 54 08 N | 080 39 47 W |
| First Baptist Church of Lake View | Church | 27 | Dillon | 34 20 42 N | 079 09 56 W |
| First Christian Church | Church | 27 | Colleton | 32 54 01 N | 080 39 37 W |
| Flowers Point | Cape | 27 | Barnwell | 33 11 51 N | 081 45 23 W |
| Floyd Tabernacle | Church | 27 | Williamsburg | 33 50 52 N | 079 53 15 W |
| Floyds School | School | 27 | Horry | 34 11 30 N | 079 03 53 W |
| Fork Swamp Hunting Club | Locale | 27 | Richland | 33 45 43 N | 080 37 34 W |
| Fowler Cemetery | Cemetery | 27 | Horry | 34 07 24 N | 078 53 25 W |
| Fox Bay | Swamp | 27 | Marion | 34 08 54 N | 079 16 30 W |
| Friendship Cemetery | Cemetery | 27 | Berkeley | 33 17 58 N | 080 10 01 W |
| Friendship Church | Church | 27 | Berkeley | 33 17 58 N | 080 10 00 W |
| Friendship School (historical) | School | 27 | Florence | 33 59 02 N | 079 40 18 W |
| Gaddys Mill | Populated Place | 27 | Dillon | 34 23 40 N | 079 14 13 W |
| Gaddys Millpond D-0512 Dam | Dam | 27 | Marion | 34 10 19 N | 079 20 59 W |
| Gadsden Acres (subdivision) | Populated Place | 27 | Dorchester | 33 01 03 N | 080 12 10 W |
| Galilee Church | Church | 27 | Berkeley | 33 19 03 N | 080 10 21 W |
| Galilee Church | Church | 27 | Orangeburg | 33 18 53 N | 080 21 30 W |
| Garbon Subdivision | Populated Place | 27 | Dorchester | 33 00 16 N | 080 10 24 W |
| Genoa | Populated Place | 27 | Marlboro | 34 27 23 N | 079 39 43 W |
| Glendale School | School | 27 | Florence | 33 54 11 N | 079 49 48 W |
| Grant School (historical) | School | 27 | Hampton | 32 41 02 N | 081 15 50 W |
| Grays School | School | 27 | Jasper | 32 40 27 N | 081 01 17 W |
| Green Lake | Lake | 27 | Sumter | 33 50 13 N | 080 35 54 W |
| Green Sea Church | Church | 27 | Horry | 34 07 44 N | 078 58 33 W |
| Green Sea-Floyds Middle School | School | 27 | Horry | 34 07 37 N | 078 58 26 W |
| Greenland Church | Church | 27 | Berkeley | 33 24 40 N | 080 08 32 W |
| Hampton Street Elementary School | School | 27 | Colleton | 32 54 04 N | 080 39 36 W |
| Harleyville | Populated Place | 27 | Dorchester | 33 12 53 N | 080 26 52 W |
| Harleyville Cemetery | Cemetery | 27 | Dorchester | 33 12 03 N | 080 27 06 W |
| Hebron Church | Church | 27 | Florence | 33 58 50 N | 079 40 30 W |
| High Island | Island | 27 | Sumter | 33 52 57 N | 080 35 08 W |
| Hillside Church | Church | 27 | Florence | 34 09 39 N | 079 43 26 W |
| Hope (historical) | Populated Place | 27 | Berkeley | 33 13 26 N | 080 17 24 W |
| Hope Graded School (historical) | School | 27 | Berkeley | 33 13 35 N | 080 17 31 W |
| Hopewell Cemetery | Cemetery | 27 | Dillon | 34 16 50 N | 079 16 21 W |
| Horse Island | Island | 27 | Chesterfield | 34 45 08 N | 079 54 22 W |
| Horsegall | Populated Place | 27 | Hampton | 32 44 39 N | 081 02 37 W |
| Howard | Populated Place | 27 | Horry | 34 06 45 N | 078 52 33 W |
| Howells | Populated Place | 27 | Horry | 33 58 36 N | 078 59 53 W |
| Huntington Farms | Populated Place | 27 | Dorchester | 33 01 28 N | 080 12 59 W |
| Hunts Bluff School (historical) | School | 27 | Marlboro | 34 29 03 N | 079 41 51 W |
| Hunts Bluff School (historical) | School | 27 | Marlboro | 34 29 17 N | 079 43 09 W |
| Huttos Lake | Reservoir | 27 | Calhoun | 33 35 31 N | 080 36 47 W |
| Indian Field School | School | 27 | Dorchester | 33 15 04 N | 080 31 15 W |
| Interchange 62 | Crossing | 27 | Colleton | 33 00 10 N | 080 40 09 W |
| Interchange 68 | Crossing | 27 | Colleton | 33 05 04 N | 080 39 09 W |
| Jehovah Church | Church | 27 | Berkeley | 33 21 40 N | 080 10 59 W |
| Jerusalem Church | Church | 27 | Hampton | 32 46 37 N | 080 58 25 W |
| Johnsonville High School | School | 27 | Florence | 33 48 59 N | 079 26 45 W |
| Johnsonville Middle School | School | 27 | Florence | 33 48 57 N | 079 26 35 W |
| Juneburn School (historical) | School | 27 | Clarendon | 33 42 45 N | 080 09 59 W |
| Kingville | Populated Place | 27 | Richland | 33 48 21 N | 080 41 51 W |
| Lake Redwing | Reservoir | 27 | Darlington | 34 19 25 N | 079 44 35 W |
| Lake View | Populated Place | 27 | Dillon | 34 20 45 N | 079 09 56 W |
| Lake View High School | School | 27 | Dillon | 34 20 39 N | 079 09 43 W |
| Lake View Middle School | School | 27 | Dillon | 34 20 36 N | 079 09 43 W |
| Lake View United Methodist Church | Church | 27 | Dillon | 34 20 35 N | 079 10 05 W |
| Lawson Pond | Lake | 27 | Berkeley | 33 22 09 N | 080 13 37 W |
| Lee Tabernacle | Church | 27 | Florence | 33 55 60 N | 079 48 02 W |
| Legare Church (historical) | Church | 27 | Berkeley | 33 17 01 N | 080 11 29 W |
| Limestone Cemetery | Cemetery | 27 | Dorchester | 33 08 51 N | 080 21 53 W |
| Limestone Church | Church | 27 | Dorchester | 33 08 52 N | 080 21 57 W |
| Little Bethel Baptist Church | Church | 27 | Marion | 34 09 33 N | 079 19 46 W |
| Little Horsepen Bay | Swamp | 27 | Marion | 34 09 44 N | 079 19 37 W |
| Little Rock Church | Church | 27 | Jasper | 32 34 59 N | 081 00 20 W |
| Lumber (historical) | Populated Place | 27 | Darlington | 34 25 05 N | 079 48 32 W |
| Mace Cemetery | Cemetery | 27 | Dillon | 34 17 34 N | 079 28 48 W |
| Malta | Populated Place | 27 | Sumter | 33 52 38 N | 080 35 02 W |
| Marion County Airport | Airport | 27 | Marion | 34 10 52 N | 079 20 04 W |
| Marks Creek | Stream | 27 | Marlboro | 34 47 35 N | 079 55 55 W |
| McAlhany Cemetery | Cemetery | 27 | Orangeburg | 33 11 21 N | 080 47 26 W |
| Mill Swamp | Swamp | 27 | Horry | 34 01 05 N | 079 09 32 W |
| Mosquito Bay | Swamp | 27 | Berkeley | 33 13 60 N | 080 14 30 W |