Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Mount Carmel School (historical) | School | 24 | Colleton | 33 00 02 N | 080 41 39 W |
| Mount Clair Baptist Church | Church | 24 | Florence | 33 51 57 N | 079 45 06 W |
| Mount Olive | Populated Place | 24 | Horry | 34 08 49 N | 079 01 57 W |
| Mount Pisgah Church | Church | 24 | Florence | 34 13 50 N | 079 40 26 W |
| Mount Pleasant Church (historical) | Church | 24 | Hampton | 32 56 53 N | 081 01 56 W |
| Mount Pleasant Plantation Cemetery | Cemetery | 24 | Berkeley | 33 22 54 N | 080 12 30 W |
| Mount Vernon Cemetery | Cemetery | 24 | Williamsburg | 33 42 18 N | 079 57 21 W |
| Mount Vernon Church | Church | 24 | Williamsburg | 33 42 17 N | 079 57 20 W |
| Murrell (historical) | Populated Place | 24 | Berkeley | 33 25 35 N | 080 01 49 W |
| Nazareth Church | Church | 24 | Berkeley | 33 12 03 N | 080 02 11 W |
| Nazareth Church (historical) | Church | 24 | Berkeley | 33 14 22 N | 080 01 57 W |
| New Castle Church | Church | 24 | Hampton | 32 42 03 N | 081 07 04 W |
| New Hope | Populated Place | 24 | Florence | 34 01 04 N | 079 45 03 W |
| New Hope Cemetery | Cemetery | 24 | Berkeley | 33 06 25 N | 080 11 18 W |
| New Hope Church | Church | 24 | Hampton | 32 48 09 N | 081 07 07 W |
| New Hope School (historical) | School | 24 | Berkeley | 33 06 22 N | 080 11 15 W |
| Newcastle School | School | 24 | Hampton | 32 41 59 N | 081 07 07 W |
| Oakman Church | Church | 24 | Colleton | 33 03 15 N | 080 38 49 W |
| Oaks Church | Church | 24 | Clarendon | 33 31 16 N | 080 23 58 W |
| Oaks School (historical) | School | 24 | Clarendon | 33 31 25 N | 080 24 52 W |
| Old Peru | Populated Place | 24 | Berkeley | 33 25 14 N | 079 59 12 W |
| Oldfield Plantation Cemetery | Cemetery | 24 | Berkeley | 33 26 22 N | 079 58 24 W |
| Palmer Chapel (historical) | Church | 24 | Berkeley | 33 23 23 N | 080 03 46 W |
| Pamplico United Methodist Church | Church | 24 | Florence | 33 59 42 N | 079 34 11 W |
| Paradise Point | Cape | 24 | Clarendon | 33 37 04 N | 080 29 44 W |
| Parkers Ferry (historical) | Crossing | 24 | Marlboro | 34 48 24 N | 079 55 43 W |
| Pattillo (historical) | Populated Place | 24 | Colleton | 32 58 53 N | 080 46 11 W |
| Pigeon Bay | Swamp | 24 | Clarendon | 33 38 35 N | 080 02 27 W |
| Pine Grove Cemetery | Cemetery | 24 | Colleton | 32 53 21 N | 080 48 16 W |
| Pine Grove Church | Church | 24 | Clarendon | 33 32 44 N | 080 04 51 W |
| Pine Grove Number 1 Baptist Church | Church | 24 | Colleton | 32 53 23 N | 080 48 22 W |
| Pine Grove School | School | 24 | Horry | 34 05 56 N | 079 03 03 W |
| Pine Island | Island | 24 | Berkeley | 33 25 51 N | 080 11 36 W |
| Pine Island | Island | 24 | Clarendon | 33 28 46 N | 080 21 14 W |
| Pine Level Baptist Church | Church | 24 | Jasper | 32 42 04 N | 081 01 43 W |
| Pineforest Inn (subdivision) | Populated Place | 24 | Dorchester | 33 00 28 N | 080 11 46 W |
| Pineville | Populated Place | 24 | Berkeley | 33 25 42 N | 080 01 45 W |
| Pineville Lookout Tower | Tower | 24 | Berkeley | 33 26 29 N | 080 03 59 W |
| Piney Grove School | School | 24 | Colleton | 32 57 34 N | 080 58 57 W |
| Pinkey Landing | Locale | 24 | Orangeburg | 33 30 08 N | 080 27 42 W |
| Pinopolis School (historical) | School | 24 | Berkeley | 33 14 15 N | 080 02 04 W |
| Pintail Island | Island | 24 | Berkeley | 33 23 55 N | 080 09 15 W |
| Playcards | Populated Place | 24 | Horry | 34 03 17 N | 079 00 21 W |
| Pleasant View Church | Church | 24 | Horry | 34 05 54 N | 079 03 47 W |
| Red Root School (historical) | School | 24 | Colleton | 32 57 20 N | 080 49 06 W |
| Redeemer Church | Church | 24 | Berkeley | 33 25 42 N | 080 01 53 W |
| Redeemer School (historical) | School | 24 | Berkeley | 33 26 23 N | 080 03 39 W |
| Region Town (historical) | Populated Place | 24 | Berkeley | 33 26 44 N | 080 01 47 W |
| Richmond Cemetery | Cemetery | 24 | Williamsburg | 33 31 36 N | 079 58 21 W |
| Ridge Cemetery | Cemetery | 24 | Berkeley | 33 02 32 N | 080 06 39 W |
| Ridgeville Church | Church | 24 | Hampton | 32 43 39 N | 080 53 42 W |
| Roadside School (historical) | School | 24 | Colleton | 33 00 27 N | 080 38 12 W |
| Robbins Neck Station (historical) | Locale | 24 | Darlington | 34 27 51 N | 079 47 32 W |
| Robinson Auditorium | Building | 24 | Florence | 33 51 21 N | 079 45 48 W |
| Rock Pond Campground | Locale | 24 | Orangeburg | 33 24 03 N | 080 13 52 W |
| Rock Spring School (historical) | School | 24 | Jasper | 32 40 09 N | 080 59 04 W |
| Rocks Cemetery | Cemetery | 24 | Berkeley | 33 24 48 N | 080 11 57 W |
| Rocks Church (historical) | Church | 24 | Berkeley | 33 24 44 N | 080 11 57 W |
| Ronald E McNair Junior High School | School | 24 | Florence | 33 52 08 N | 079 46 03 W |
| Rosehill (subdivision) | Populated Place | 24 | Dorchester | 33 00 12 N | 080 11 17 W |
| Round Island | Island | 24 | Clarendon | 33 29 35 N | 080 16 33 W |
| Ruddell (historical) | Populated Place | 24 | Allendale | 32 50 56 N | 081 24 24 W |
| Rum Gully School (historical) | School | 24 | Colleton | 33 01 53 N | 080 54 04 W |
| Russellville | Populated Place | 24 | Berkeley | 33 23 50 N | 079 58 18 W |
| Russellville Post Office | Post Office | 24 | Berkeley | 33 24 33 N | 079 59 10 W |
| Russellville School (historical) | School | 24 | Berkeley | 33 24 28 N | 079 58 45 W |
| Saint James School | School | 24 | Marion | 34 03 40 N | 079 18 50 W |
| Saint John Church | Church | 24 | Hampton | 32 52 40 N | 080 58 44 W |
| Saint John School (historical) | School | 24 | Hampton | 32 52 40 N | 080 58 44 W |
| Saint Johns | Populated Place | 24 | Berkeley | 33 07 15 N | 080 04 08 W |
| Saint Johns Cemetery | Cemetery | 24 | Florence | 33 54 09 N | 079 37 41 W |
| Saint Johns Church | Church | 24 | Williamsburg | 33 41 44 N | 079 58 56 W |
| Saint Johns Race Track (historical) | Locale | 24 | Orangeburg | 33 24 58 N | 080 17 28 W |
| Saint Lukes Church (historical) | Church | 24 | Berkeley | 33 25 16 N | 080 07 41 W |
| Saint Marks Camp Ground (historical) | Locale | 24 | Hampton | 32 41 09 N | 081 18 09 W |
| Saint Marys Holiness Church | Church | 24 | Berkeley | 33 24 28 N | 079 58 58 W |
| Saint Paul Cemetery | Cemetery | 24 | Florence | 34 05 54 N | 079 38 19 W |
| Saint Paul School (historical) | School | 24 | Dorchester | 33 12 10 N | 080 29 07 W |
| Saint Pauls Church | Church | 24 | Dorchester | 33 12 09 N | 080 29 07 W |
| Saint Peter Church | Church | 24 | Florence | 33 54 01 N | 079 47 21 W |
| Saint Stephen | Populated Place | 24 | Berkeley | 33 24 16 N | 079 55 18 W |
| Saint Stephen Cemetery | Cemetery | 24 | Berkeley | 33 23 34 N | 079 55 06 W |
| Saint Stephen Elementary School | School | 24 | Berkeley | 33 23 56 N | 079 55 44 W |
| Saint Stephen High School | School | 24 | Berkeley | 33 23 41 N | 079 56 35 W |
| Saint Stephen Post Office | Post Office | 24 | Berkeley | 33 24 19 N | 079 55 26 W |
| Saint Stephens Cemetery | Cemetery | 24 | Berkeley | 33 24 19 N | 079 55 00 W |
| Saint Stephens Episcopal Church | Church | 24 | Berkeley | 33 24 20 N | 079 55 00 W |
| Salem Church | Church | 24 | Berkeley | 33 02 54 N | 080 06 35 W |
| Sand Hill Original Church | Church | 24 | Florence | 34 01 02 N | 079 47 22 W |
| Sand Hill School (historical) | School | 24 | Hampton | 32 41 07 N | 081 19 09 W |
| Sand Ridge | Island | 24 | Sumter | 33 46 49 N | 080 34 12 W |
| Sandhill Church | Church | 24 | Hampton | 32 41 13 N | 081 19 08 W |
| Sandhill School | School | 24 | Florence | 34 13 50 N | 079 40 20 W |
| Sandridge | Populated Place | 24 | Berkeley | 33 15 19 N | 080 18 57 W |
| Sandy Grove Church | Church | 24 | Williamsburg | 33 48 59 N | 079 53 56 W |
| Sandy Hill School (historical) | School | 24 | Florence | 34 01 07 N | 079 47 16 W |
| Santee Canal | Canal | 24 | Berkeley | 33 25 36 N | 080 06 07 W |
| Santee National Wildlife Refuge | Park | 24 | Clarendon | 33 29 54 N | 080 18 01 W |
| Shoe Lake | Lake | 24 | Sumter | 33 46 56 N | 080 35 28 W |
| Slader Nelson School (historical) | School | 24 | Clarendon | 33 32 19 N | 080 19 46 W |
| Sniders School (historical) | School | 24 | Colleton | 32 53 25 N | 080 50 17 W |
| Solomons Cemetery | Cemetery | 24 | Hampton | 32 40 45 N | 081 19 41 W |
| South Carolina Noname 14013 D-3503 Dam | Dam | 24 | Clarendon | 33 34 37 N | 080 13 17 W |
| South Carolina Noname 16008 D-3540 Dam | Dam | 24 | Darlington | 34 23 55 N | 079 46 53 W |
| South Carolina Noname 25021 D-2598 Dam | Dam | 24 | Hampton | 32 41 49 N | 081 19 23 W |
| South Carolina Noname 26001 D-3608 Dam | Dam | 24 | Horry | 34 13 19 N | 079 02 12 W |
| South Carolina Noname 27002 D-2585 Dam | Dam | 24 | Jasper | 32 31 43 N | 081 00 29 W |
| South Carolina Noname 38036 D-3743 Dam | Dam | 24 | Orangeburg | 33 31 19 N | 080 30 53 W |
| Spring Branch Church | Church | 24 | Florence | 34 04 51 N | 079 35 38 W |
| Spring Hill Church | Church | 24 | Orangeburg | 33 24 25 N | 080 17 48 W |