Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Isaqueena School Number 1 (historical) | School | 277 | Oconee | 34 49 29 N | 082 55 03 W |
| Isaqueena School Number 2 (historical) | School | 302 | Oconee | 34 51 56 N | 082 55 07 W |
| Isaqueena Village (subdivision) | Populated Place | 269 | Pickens | 34 42 22 N | 082 47 32 W |
| Isbell Heights (subdivision) | Populated Place | 307 | Greenville | 34 49 09 N | 082 20 47 W |
| Iseman Crossroads | Populated Place | 52 | Darlington | 34 16 08 N | 079 57 10 W |
| Isgett Circle | Populated Place | 54 | Chesterfield | 34 42 06 N | 079 56 09 W |
| Isinglass Swamp | Swamp | 2 | Charleston | 32 43 16 N | 080 06 59 W |
| Island Branch | Stream | | Berkeley | 33 16 10 N | 079 54 22 W |
| Island Branch | Stream | | Williamsburg | 33 44 09 N | 079 23 13 W |
| Island Cemeteries | Cemetery | 44 | Orangeburg | 33 25 34 N | 080 34 20 W |
| Island Creek | Stream | | Aiken | 33 13 29 N | 081 46 32 W |
| Island Creek | Stream | | Spartanburg | 35 02 19 N | 081 50 50 W |
| Island Creek Cemetery | Cemetery | 290 | Cherokee | 35 05 04 N | 081 48 40 W |
| Island Creek Church | Church | 289 | Cherokee | 35 05 06 N | 081 48 44 W |
| Island Creek School (historical) | School | 277 | Cherokee | 35 05 36 N | 081 48 41 W |
| Island Creek School (historical) | School | 273 | Cherokee | 35 09 40 N | 081 42 43 W |
| Island Cut | Channel | 0 | Charleston | 33 04 29 N | 079 26 54 W |
| Island Ferry (historical) | Crossing | 131 | Cherokee | 35 01 37 N | 081 29 21 W |
| Island Lake | Lake | 33 | Aiken | 33 20 51 N | 081 54 00 W |
| Island of Palms | Island | 2 | Charleston | 32 47 58 N | 079 45 45 W |
| Island of Palms | Populated Place | 0 | Charleston | 32 47 25 N | 079 47 03 W |
| Island Palm Marina | Locale | -5 | Charleston | 32 48 21 N | 079 45 42 W |
| Island School | School | 42 | Orangeburg | 33 25 40 N | 080 33 59 W |
| Island Square Shopping Center | Locale | 4 | Beaufort | 32 24 53 N | 080 39 10 W |
| Island View Landing | Populated Place | 174 | York | 35 01 32 N | 081 02 35 W |
| Islanded Bay | Swamp | 30 | Clarendon | 33 37 22 N | 080 05 43 W |
| Islandton | Populated Place | 19 | Colleton | 32 54 33 N | 080 56 07 W |
| Islandton School (historical) | School | 22 | Colleton | 32 54 39 N | 080 56 47 W |
| Islay (historical) | Populated Place | 44 | Marlboro | 34 37 27 N | 079 43 38 W |
| Isle of Palms | Populated Place | 0 | Charleston | 32 47 13 N | 079 47 41 W |
| Isle of Palms Baptist Church | Church | 1 | Charleston | 32 47 32 N | 079 46 49 W |
| Isle of Palms City Hall | Building | 1 | Charleston | 32 47 23 N | 079 47 13 W |
| Isle of Palms Post Office | Post Office | 4 | Charleston | 32 47 08 N | 079 47 24 W |
| Isle of Palms Post Office (historical) | Post Office | 0 | Charleston | 32 47 13 N | 079 47 41 W |
| Isle of Pines | Populated Place | 158 | Laurens | 34 20 00 N | 082 06 08 W |
| Isoms Creek | Stream | | Spartanburg | 34 52 31 N | 081 47 07 W |
| Isqett Cemetery | Cemetery | 46 | Darlington | 34 20 23 N | 079 48 50 W |
| Israel Christian Methodist Episcopal Church | Church | 300 | Greenville | 34 50 48 N | 082 24 48 W |
| Israelite Church | Church | 7 | Beaufort | 32 26 40 N | 080 38 26 W |
| Issaqueena Lake | Reservoir | 202 | Oconee | 34 44 06 N | 082 51 52 W |
| Issaqueena Lookout Tower | Tower | 293 | Pickens | 34 44 33 N | 082 50 19 W |
| Italy | Populated Place | 7 | Georgetown | 33 26 55 N | 079 32 27 W |
| Iva | Populated Place | 217 | Anderson | 34 18 23 N | 082 39 49 W |
| Iva Baptist Church | Church | 219 | Anderson | 34 18 21 N | 082 39 40 W |
| Iva Elementary School | School | 221 | Anderson | 34 18 51 N | 082 39 58 W |
| Iva Field | Airport | 198 | Anderson | 34 17 49 N | 082 41 01 W |
| Iva Post Office | Post Office | 216 | Anderson | 34 18 21 N | 082 39 47 W |
| Ivanhoe Bridge | Bridge | 1 | Colleton | 32 45 56 N | 080 37 05 W |
| Ivanhoe Shopping Center | Locale | 23 | Colleton | 32 55 48 N | 080 41 34 W |
| Ivenia Brown Elementary School | School | 4 | Colleton | 32 43 38 N | 080 36 22 W |
| Ivester Lake | Reservoir | 251 | Anderson | 34 30 24 N | 082 31 17 W |
| Ivey Hall | Populated Place | 47 | Sumter | 33 53 36 N | 080 21 54 W |
| Ivory Lake | Lake | 6 | Jasper | 32 28 27 N | 081 11 38 W |
| Izards Mill (historical) | Locale | 143 | Lancaster | 34 47 04 N | 080 52 25 W |
| J A Bedenbaugh Pond | Reservoir | 205 | Laurens | 34 26 36 N | 082 02 35 W |
| J A Bedenbaugh Pond Dam D-3016 | Dam | 205 | Laurens | 34 26 36 N | 082 02 35 W |
| J A Holmes Pond | Reservoir | 180 | Saluda | 33 53 49 N | 081 35 17 W |
| J A Holmes Pond Dam D-1199 | Dam | 180 | Saluda | 33 53 49 N | 081 35 17 W |
| J B Beck Middle School | School | 4 | Georgetown | 33 22 56 N | 079 17 45 W |
| J B Greer Pond Dam D-2888 | Dam | 276 | Greenville | 34 45 54 N | 082 19 29 W |
| J B Johnson Pond | Reservoir | 319 | Spartanburg | 35 03 24 N | 082 08 17 W |
| J B Johnson Pond Dam D-3315 | Dam | 319 | Spartanburg | 35 03 24 N | 082 08 17 W |
| J Ballentine Pond | Reservoir | 11 | Berkeley | 33 09 37 N | 080 09 41 W |
| J Brockman Pond Dam D-2788 | Dam | 239 | Spartanburg | 34 48 54 N | 082 10 05 W |
| J C Lynch Consolidated School | School | 28 | Florence | 33 58 18 N | 079 45 05 W |
| J C Petty Pond Dam D-3331 | Dam | 259 | Spartanburg | 35 04 00 N | 081 54 59 W |
| J C Watson Pond | Reservoir | 180 | Saluda | 33 51 31 N | 081 38 59 W |
| J C Watson Pond Dam D-1601 | Dam | 180 | Saluda | 33 51 31 N | 081 38 59 W |
| J D Lever School | School | 86 | Aiken | 33 22 32 N | 081 49 16 W |
| J E Beard Chapel | Church | 4 | Charleston | 32 47 38 N | 079 56 11 W |
| J E Powe Pond | Reservoir | 37 | Marlboro | 34 43 31 N | 079 50 53 W |
| J G Holliday Pond | Reservoir | 20 | Florence | 33 55 07 N | 079 33 41 W |
| J G Holliday Pond Dam D-3581 | Dam | 20 | Florence | 33 55 07 N | 079 33 41 W |
| J G McCracken Junior High School | School | 242 | Spartanburg | 34 58 32 N | 081 52 14 W |
| J H Holliday Pond | Reservoir | 15 | Florence | 33 53 19 N | 079 31 29 W |
| J H Holliday Pond Dam D-3584 | Dam | 15 | Florence | 33 53 19 N | 079 31 29 W |
| J H Page Lake Dam D-2760 | Dam | 195 | Spartanburg | 34 54 30 N | 081 55 29 W |
| J Hopkins Pond Dam D-3155 | Dam | 244 | Anderson | 34 39 12 N | 082 45 24 W |
| J J Padgett Pond | Reservoir | 20 | Colleton | 33 01 07 N | 080 50 17 W |
| J K Gourdine Elementary School | School | 24 | Berkeley | 33 25 32 N | 079 59 25 W |
| J L Mann High School | School | 307 | Greenville | 34 48 42 N | 082 20 43 W |
| J L Wannamaker Cabin Pond | Reservoir | 76 | Calhoun | 33 42 01 N | 080 42 35 W |
| J L Wannamaker Pond | Reservoir | 54 | Calhoun | 33 42 01 N | 080 47 17 W |
| J L Wannamaker Pond Dam D-2685 | Dam | 54 | Calhoun | 33 42 01 N | 080 47 17 W |
| J M Gentry Pond | Reservoir | 277 | Spartanburg | 35 01 18 N | 082 05 41 W |
| J M Gentry Pond Dam D-3320 | Dam | 277 | Spartanburg | 35 01 18 N | 082 05 41 W |
| J P Gamble Pond | Reservoir | 8 | Williamsburg | 33 28 31 N | 079 56 23 W |
| J P Gamble Pond Dam | Dam | 8 | Williamsburg | 33 28 31 N | 079 56 23 W |
| J P Stevens Pond | Reservoir | 262 | Greenville | 34 50 30 N | 082 14 11 W |
| J P Stevens Pond | Reservoir | 31 | Marlboro | 34 42 49 N | 079 51 47 W |
| J P Stevens Pond Dam D-2901 | Dam | 262 | Greenville | 34 50 30 N | 082 14 11 W |
| J Paul Beam Elementary School | School | 257 | Cherokee | 35 06 19 N | 081 42 15 W |
| J Paul Trulock Elementary School | School | 24 | Florence | 33 53 18 N | 079 45 57 W |
| J Stooksburry Pond Dam D-1121 | Dam | 344 | Greenville | 35 03 00 N | 082 26 47 W |
| J V Martin Junior High School | School | 36 | Dillon | 34 25 16 N | 079 22 24 W |
| J W Cowan Pond Dam D-3149 | Dam | 215 | Anderson | 34 25 06 N | 082 27 29 W |
| J W Crocker Pond | Reservoir | 213 | Spartanburg | 34 57 36 N | 081 46 17 W |
| J W Crocker Pond Dam D-3373 | Dam | 213 | Spartanburg | 34 57 36 N | 081 46 17 W |
| J W Smoaks Pond | Reservoir | 53 | Orangeburg | 33 31 31 N | 080 56 05 W |
| J W Wilson Pond Dam D-3031 | Dam | 191 | Abbeville | 34 16 24 N | 082 34 05 W |
| J Williams Pond Dam D-1173 | Dam | 387 | Greenville | 35 06 18 N | 082 26 47 W |
| J. Strom Thurmond Reservoir | Reservoir | 104 | McCormick | 33 39 40 N | 082 11 57 W |
| Jack Branch | Stream | | Orangeburg | 33 24 35 N | 080 31 34 W |
| Jack Creek | Gut | 0 | Charleston | 32 55 22 N | 079 34 56 W |
| Jack Crow Island | Island | 3 | Beaufort | 32 09 26 N | 080 53 04 W |
| Jack Hill | Ridge | 6 | Georgetown | 33 16 43 N | 079 31 03 W |
| Jack Hole | Lake | 30 | Sumter | 33 55 27 N | 080 37 09 W |
| Jack Island | Island | 3 | Beaufort | 32 10 23 N | 080 52 03 W |
| Jack Island | Island | 0 | Beaufort | 32 30 26 N | 080 41 08 W |
| Jack Lake | Lake | 9 | Horry | 34 01 42 N | 079 17 55 W |