Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Alexander Creek | Stream | | Spartanburg | 35 06 53 N | 082 06 17 W |
| Alexander Crossroads | Populated Place | 46 | Darlington | 34 11 50 N | 079 55 49 W |
| Alexander Elementary School | School | 305 | Greenville | 34 51 22 N | 082 26 23 W |
| Alexander Hill | Summit | 368 | Pickens | 34 59 48 N | 082 34 39 W |
| Alexander School (historical) | School | 48 | Darlington | 34 13 38 N | 079 54 29 W |
| Alexander School (historical) | School | 224 | Spartanburg | 34 57 23 N | 081 55 37 W |
| Alexanders Mill (historical) | Locale | 202 | Greenville | 34 37 23 N | 082 18 12 W |
| Alexanders Store (historical) | Locale | 424 | Pickens | 35 00 10 N | 082 48 14 W |
| Alford Branch | Stream | | Florence | 34 14 24 N | 079 36 31 W |
| Alford Cemetery | Cemetery | 47 | Dillon | 34 28 55 N | 079 28 56 W |
| Alfords Bridge (historical) | Bridge | 201 | Anderson | 34 23 01 N | 082 50 14 W |
| Alfred Creek | Stream | | Horry | 33 49 18 N | 079 13 43 W |
| Algary (historical) | Populated Place | 207 | Greenwood | 34 21 56 N | 082 16 44 W |
| Algary School (historical) | School | 216 | Greenwood | 34 21 30 N | 082 18 04 W |
| Alice Birney Middle School | School | 12 | Charleston | 32 56 34 N | 080 03 20 W |
| Alice Drive Elementary School | School | 54 | Sumter | 33 55 58 N | 080 22 39 W |
| Alice Drive Junior High School | School | 53 | Sumter | 33 55 58 N | 080 22 37 W |
| Alice Methodist Church | Church | 327 | Pickens | 34 49 59 N | 082 37 10 W |
| Alice Mill School | School | 340 | Pickens | 34 49 49 N | 082 37 12 W |
| All Saints Anglican Church | Church | 158 | Aiken | 33 33 36 N | 081 42 57 W |
| All Saints Cemetery | Cemetery | 3 | Georgetown | 33 28 03 N | 079 08 24 W |
| All Saints Church | Church | 122 | Aiken | 33 25 24 N | 081 51 37 W |
| All Saints Church | Church | 3 | Georgetown | 33 28 04 N | 079 08 22 W |
| All Saints Episcopal Church | Church | 38 | Clarendon | 33 41 38 N | 080 12 46 W |
| All Saints Episcopal Church | Church | 43 | Florence | 34 11 08 N | 079 47 37 W |
| All Saints Episcopal Church | Church | 198 | Laurens | 34 28 06 N | 081 52 21 W |
| Allen | Populated Place | 18 | Horry | 33 55 17 N | 079 02 26 W |
| Allen Acres (subdivision) | Populated Place | 225 | Spartanburg | 34 58 40 N | 081 55 35 W |
| Allen Benedict Court (subdivision) | Populated Place | 82 | Richland | 34 00 54 N | 081 01 19 W |
| Allen Cemetery | Cemetery | 3 | Beaufort | 32 13 50 N | 081 00 03 W |
| Allen Cemetery | Cemetery | 29 | Dillon | 34 18 55 N | 079 23 50 W |
| Allen Cemetery | Cemetery | 15 | Marion | 34 05 53 N | 079 15 58 W |
| Allen Chapel | Church | 177 | Abbeville | 34 11 54 N | 082 15 34 W |
| Allen Chapel | Church | 216 | Spartanburg | 34 53 55 N | 081 52 50 W |
| Allen Chapel | Church | 52 | Sumter | 33 54 24 N | 080 23 10 W |
| Allen Chapel | Church | 21 | Williamsburg | 33 44 60 N | 079 50 55 W |
| Allen Chapel (historical) | Church | 52 | Allendale | 33 00 37 N | 081 15 40 W |
| Allen Chapel Cemetery | Cemetery | 52 | Allendale | 33 00 38 N | 081 15 39 W |
| Allen Chapel School (historical) | School | 21 | Williamsburg | 33 44 58 N | 079 51 00 W |
| Allen Church | Church | 9 | Beaufort | 32 28 46 N | 080 44 13 W |
| Allen Church | Church | 2 | Charleston | 32 33 07 N | 080 16 37 W |
| Allen Church | Church | 8 | Charleston | 32 41 51 N | 080 15 41 W |
| Allen Church | Church | 21 | Williamsburg | 33 45 11 N | 079 50 58 W |
| Allen Creek | Stream | | Abbeville | 34 10 04 N | 082 43 24 W |
| Allen Creek | Stream | | Colleton | 32 59 26 N | 080 37 27 W |
| Allen Hills (subdivision) | Populated Place | 234 | Anderson | 34 31 05 N | 082 38 29 W |
| Allen Knob | Summit | 455 | Greenville | 35 04 36 N | 082 24 46 W |
| Allen Meadow | Swamp | 9 | Colleton | 32 46 60 N | 080 26 46 W |
| Allen Park | Park | 197 | Anderson | 34 27 25 N | 082 35 30 W |
| Allen Shoals | Rapids | 228 | Greenville | 34 39 47 N | 082 27 49 W |
| Allen Temple | Church | 232 | Cherokee | 35 04 51 N | 081 38 58 W |
| Allen Temple African Methodist Episcopal Church | Church | 309 | Greenville | 34 50 29 N | 082 24 32 W |
| Allen University | School | 89 | Richland | 34 00 39 N | 081 01 13 W |
| Allendale | Populated Place | 57 | Allendale | 33 00 29 N | 081 18 30 W |
| Allendale | Populated Place | 210 | Anderson | 34 25 47 N | 082 45 29 W |
| Allendale Academy | School | 55 | Allendale | 33 00 53 N | 081 18 08 W |
| Allendale County | Civil | 59 | Allendale | 33 00 02 N | 081 20 59 W |
| Allendale County African-American Cultural Center | Building | 57 | Allendale | 33 00 31 N | 081 18 36 W |
| Allendale County Airport | Airport | 47 | Allendale | 32 59 42 N | 081 16 12 W |
| Allendale County Courthouse | Building | 58 | Allendale | 33 00 48 N | 081 18 22 W |
| Allendale County Hospital | Hospital | 39 | Allendale | 32 57 58 N | 081 14 55 W |
| Allendale County Museum | Building | 56 | Allendale | 33 00 48 N | 081 18 14 W |
| Allendale Elementary School | School | 54 | Allendale | 32 59 59 N | 081 18 04 W |
| Allendale Fairfax High School | School | 44 | Allendale | 32 58 57 N | 081 16 22 W |
| Allendale Fairfax Middle School | School | 44 | Allendale | 32 58 57 N | 081 16 21 W |
| Allendale Primary School | School | 57 | Allendale | 33 00 13 N | 081 19 17 W |
| Allendale War Memorial Building | Building | 58 | Allendale | 33 00 45 N | 081 18 20 W |
| Allens Bridge | Bridge | 16 | Dillon | 34 15 59 N | 079 12 58 W |
| Allens Bridge | Bridge | 171 | Spartanburg | 34 43 07 N | 082 04 09 W |
| Allens Chapel | Church | 59 | Barnwell | 33 07 57 N | 081 14 27 W |
| Allens Mill (historical) | Locale | 86 | Chester | 34 32 59 N | 080 53 14 W |
| Allens School | School | 26 | Horry | 33 56 43 N | 079 04 48 W |
| Allens View Church | Church | 249 | Spartanburg | 34 51 42 N | 082 07 01 W |
| Allentown | Populated Place | 12 | Georgetown | 33 37 34 N | 079 21 01 W |
| Alligator Bay | Swamp | 51 | Bamberg | 33 09 19 N | 081 08 36 W |
| Alligator Bay | Swamp | 32 | Florence | 34 01 59 N | 079 41 19 W |
| Alligator Bay | Swamp | 22 | Horry | 34 11 36 N | 079 06 46 W |
| Alligator Bay | Swamp | 14 | Williamsburg | 33 26 60 N | 079 40 24 W |
| Alligator Branch | Stream | | Florence | 34 07 31 N | 079 48 26 W |
| Alligator Branch | Stream | | Sumter | 33 56 18 N | 080 14 41 W |
| Alligator Bridge | Bridge | 6 | Berkeley | 33 08 41 N | 079 51 28 W |
| Alligator Creek | Gut | 0 | Charleston | 33 05 54 N | 079 21 49 W |
| Alligator Creek | Gut | 0 | Charleston | 33 08 10 N | 079 18 56 W |
| Alligator Creek | Stream | | Berkeley | 33 08 10 N | 079 49 28 W |
| Alligator Creek | Stream | | Charleston | 32 39 11 N | 080 00 56 W |
| Alligator Creek | Stream | | Colleton | 32 33 45 N | 080 24 35 W |
| Alligator Creek | Stream | | Darlington | 34 18 29 N | 079 44 04 W |
| Alligator Creek | Stream | | Jasper | 32 41 10 N | 081 05 14 W |
| Alligator Lake | Lake | 13 | Marion | 34 09 52 N | 079 12 05 W |
| Alligator Lake | Lake | 33 | Richland | 33 55 22 N | 080 59 39 W |
| Alligator Lake | Populated Place | 35 | Florence | 34 07 32 N | 079 48 15 W |
| Alligator Pond | Lake | 6 | Horry | 33 46 44 N | 078 45 53 W |
| Alligator Run | Stream | | Marion | 33 55 05 N | 079 18 58 W |
| Alligator Swamp | Stream | | Horry | 33 56 17 N | 078 55 19 W |
| Allison Creek | Stream | | Cherokee | 35 06 55 N | 081 38 15 W |
| Allison Creek | Stream | | York | 35 01 50 N | 081 02 32 W |
| Allison Creek Church | Church | 220 | York | 35 03 48 N | 081 13 49 W |
| Allison Creek Church | Church | 214 | York | 35 02 26 N | 081 06 07 W |
| Allison Ferry (historical) | Crossing | 3 | Florence | 33 53 07 N | 079 24 34 W |
| Allison School (historical) | School | 279 | Greenville | 35 01 12 N | 082 33 44 W |
| Allisons Branch | Stream | | Laurens | 34 31 06 N | 081 47 01 W |
| Alliston Estate | Locale | 4 | Georgetown | 33 25 09 N | 079 08 22 W |
| Allowance Hall School (historical) | School | 157 | Lancaster | 34 37 29 N | 080 48 25 W |
| Allsbrook | Populated Place | 32 | Horry | 34 01 13 N | 078 56 47 W |
| Allsbrook Pond | Reservoir | 24 | Horry | 34 00 13 N | 078 58 35 W |
| Allsbrook Pond Dam D-3619 | Dam | 24 | Horry | 34 00 13 N | 078 58 35 W |
| Allsbrook School (historical) | School | 29 | Horry | 34 00 59 N | 078 56 39 W |
| Allston Creek | Stream | | Georgetown | 33 31 38 N | 079 03 11 W |
| Alma Elementary School | School | 228 | Cherokee | 35 04 54 N | 081 36 35 W |
| Almeda | Populated Place | 25 | Hampton | 32 49 48 N | 081 02 57 W |