Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Yauhannah Church | Church | 6 | Georgetown | 33 39 06 N | 079 11 14 W |
| Yauhannah Creek | Stream | | Georgetown | 33 37 42 N | 079 09 43 W |
| Yauhannah Forest Fire Tower | Tower | 6 | Georgetown | 33 38 50 N | 079 10 18 W |
| Yauhannah Lake | Lake | 1 | Georgetown | 33 39 24 N | 079 10 00 W |
| Yaupon Circle (subdivision) | Populated Place | 4 | Horry | 33 40 54 N | 078 53 36 W |
| Yaw Branch School (historical) | School | 93 | Barnwell | 33 27 10 N | 081 21 24 W |
| Yawkey-South Island Reserve | Park | 0 | Georgetown | 33 13 32 N | 079 13 19 W |
| Yeaman Hall Plaza Shopping Center | Locale | 20 | Berkeley | 32 54 05 N | 080 00 39 W |
| Yeamans Hall Plantation (historical) | Locale | 12 | Berkeley | 32 55 35 N | 079 58 41 W |
| Yeamans Hall Plantation Cemetery | Cemetery | 9 | Berkeley | 32 55 38 N | 079 58 41 W |
| Yellow Branch | Stream | | Oconee | 34 47 11 N | 083 08 01 W |
| Yellow Branch Campground | Locale | 466 | Oconee | 34 48 21 N | 083 07 42 W |
| Yellow Branch Lookout Tower | Tower | 460 | Oconee | 34 47 47 N | 083 07 19 W |
| Yellow House (historical) | Populated Place | 11 | Berkeley | 32 53 34 N | 079 55 29 W |
| Yellow House Creek | Gut | -2 | Berkeley | 32 54 60 N | 079 55 18 W |
| Yellow House Landing | Populated Place | 2 | Berkeley | 32 54 31 N | 079 55 29 W |
| Yellow Lake | Lake | 8 | Florence | 34 05 12 N | 079 32 08 W |
| Yellowjacket Island | Island | 9 | Berkeley | 33 10 20 N | 079 39 47 W |
| Yemassee | Populated Place | 13 | Hampton | 32 41 25 N | 080 51 02 W |
| Yemassee School (historical) | School | 11 | Hampton | 32 42 01 N | 080 51 14 W |
| Yenome | Populated Place | 70 | Barnwell | 33 11 01 N | 081 20 48 W |
| Yonah Dam | Dam | 225 | Oconee | 34 40 54 N | 083 20 33 W |
| Yonce Millpond | Reservoir | 131 | Aiken | 33 45 07 N | 081 42 30 W |
| Yonce Pond Dam D-1693 | Dam | 166 | Edgefield | 33 41 48 N | 081 51 29 W |
| Yonges Island | Island | 9 | Charleston | 32 41 38 N | 080 13 52 W |
| Yonges Island | Populated Place | 9 | Charleston | 32 41 37 N | 080 13 50 W |
| Yonges Island Airport | Airport | 8 | Charleston | 32 41 51 N | 080 13 33 W |
| Yonges Island Post Office | Post Office | 2 | Charleston | 32 41 25 N | 080 13 28 W |
| York | Populated Place | 232 | York | 34 59 39 N | 081 14 31 W |
| York Airport | Airport | 235 | York | 35 01 55 N | 081 15 04 W |
| York Associate Reformed Presbyterian Church | Church | 229 | York | 34 59 47 N | 081 14 24 W |
| York Bottom Creek | Stream | | Berkeley | 33 05 23 N | 079 48 10 W |
| York City Hall | Building | 228 | York | 34 59 43 N | 081 14 21 W |
| York Comprehensive High School | School | 217 | York | 34 58 03 N | 081 14 21 W |
| York County | Civil | 185 | York | 34 59 00 N | 081 10 59 W |
| York County Courthouse | Building | 231 | York | 34 59 37 N | 081 14 34 W |
| York County Hospital | Hospital | 204 | York | 34 57 03 N | 081 02 23 W |
| York County Nature Museum | Building | 201 | York | 35 00 37 N | 081 03 45 W |
| York Hills (subdivision) | Populated Place | 235 | Cherokee | 35 02 25 N | 081 39 14 W |
| York Historic District | Park | 232 | York | 34 59 39 N | 081 14 31 W |
| York Junior High School | School | 211 | York | 34 58 08 N | 081 14 18 W |
| York Plaza Shopping Center | Locale | 185 | York | 34 58 09 N | 080 59 42 W |
| York Post Office | Post Office | 229 | York | 34 59 37 N | 081 14 26 W |
| York Public Library | Building | 230 | York | 34 59 55 N | 081 14 18 W |
| York Road Elementary School | School | 198 | York | 34 56 52 N | 081 04 27 W |
| York Road School | School | 172 | Chester | 34 43 46 N | 081 12 14 W |
| York Technical College | School | 183 | York | 34 56 08 N | 080 59 42 W |
| York Terrace | Populated Place | 170 | Chester | 34 43 19 N | 081 12 25 W |
| York Village Shopping Center | Locale | 214 | York | 34 59 10 N | 081 13 24 W |
| Yorkdale | Populated Place | 209 | York | 34 54 24 N | 080 55 44 W |
| Yorkley Creek | Stream | | Jasper | 32 25 34 N | 081 12 16 W |
| Yorkshire (subdivision) | Populated Place | 67 | Richland | 33 58 57 N | 080 56 30 W |
| Yorkwood | Populated Place | 298 | Pickens | 34 48 15 N | 082 32 47 W |
| Yost Creek | Stream | | Lexington | 34 03 33 N | 081 11 52 W |
| Young Hall | Building | 220 | Pickens | 34 40 41 N | 082 50 25 W |
| Young Macedonia Cemetery | Cemetery | 157 | Edgefield | 33 37 31 N | 081 58 24 W |
| Young Macedonia Church | Church | 160 | Edgefield | 33 37 29 N | 081 58 23 W |
| Young Macedonia School (historical) | School | 140 | Edgefield | 33 37 33 N | 081 58 32 W |
| Young Memorial Associate Reformed Presbyterian Church | Church | 235 | Anderson | 34 30 53 N | 082 38 34 W |
| Young School (historical) | School | 237 | Cherokee | 35 08 20 N | 081 34 17 W |
| Young Storm Branch Church | Church | 95 | Aiken | 33 30 05 N | 081 50 34 W |
| Young Zion Church | Church | 7 | Beaufort | 32 15 47 N | 080 52 07 W |
| Young Zion Hill Church | Church | 131 | Aiken | 33 34 43 N | 081 45 24 W |
| Younginer Pond | Reservoir | 101 | Lexington | 33 54 19 N | 081 16 30 W |
| Youngs | Populated Place | 224 | Laurens | 34 40 14 N | 082 04 50 W |
| Youngs Branch | Stream | | Pickens | 34 56 38 N | 082 45 29 W |
| Youngs Bridge | Bridge | 97 | Kershaw | 34 30 28 N | 080 32 38 W |
| Youngs Bridge (historical) | Bridge | 72 | Kershaw | 34 26 33 N | 080 19 34 W |
| Youngs Chapel | Church | 168 | Greenwood | 34 11 34 N | 082 04 19 W |
| Youngs Chapel | Church | 79 | Richland | 34 01 04 N | 081 04 53 W |
| Youngs Chapel School (historical) | School | 165 | Greenwood | 34 11 32 N | 082 04 18 W |
| Youngs Ferry (historical) | Crossing | 134 | Laurens | 34 18 29 N | 082 06 36 W |
| Youngs Grove Cemetery | Cemetery | 236 | Cherokee | 35 08 17 N | 081 34 18 W |
| Youngs Grove Church | Church | 239 | Cherokee | 35 08 19 N | 081 34 17 W |
| Youngs Island | Island | 54 | Orangeburg | 33 25 11 N | 081 10 52 W |
| Youngs Pond | Reservoir | 70 | Richland | 33 58 58 N | 080 50 03 W |
| Youngs Post Office (historical) | Post Office | 223 | Laurens | 34 40 17 N | 082 04 48 W |
| Youngs School | School | 37 | Allendale | 32 59 59 N | 081 12 03 W |
| Youngs School (historical) | School | 43 | Chesterfield | 34 37 30 N | 079 52 53 W |
| Youngs School (historical) | School | 212 | Laurens | 34 40 30 N | 082 03 52 W |
| Youngs School (historical) | School | 157 | McCormick | 33 59 24 N | 082 19 30 W |
| Z L Madden Elementary School | School | 246 | Spartanburg | 34 58 19 N | 081 57 05 W |
| Zacharias Point | Cape | 4 | Jasper | 32 26 52 N | 081 12 17 W |
| Zadok (historical) | Populated Place | 241 | York | 35 04 45 N | 081 16 41 W |
| Zahler Cemetery | Cemetery | 20 | Hampton | 32 44 20 N | 080 52 53 W |
| Zeeks Branch | Stream | | Horry | 34 02 60 N | 079 00 19 W |
| Zeiglers Pond | Reservoir | 74 | Orangeburg | 33 27 25 N | 080 58 58 W |
| Zeiglers Pond | Reservoir | 69 | Orangeburg | 33 34 25 N | 080 47 17 W |
| Zekial Creek | Stream | | Cherokee | 35 06 20 N | 081 50 28 W |
| Zemp | Populated Place | 106 | Lee | 34 16 15 N | 080 19 36 W |
| Zemp Field | Park | 50 | Kershaw | 34 14 07 N | 080 36 16 W |
| Ziegenfuss Pond | Reservoir | 203 | Laurens | 34 28 48 N | 082 14 05 W |
| Ziegenfuss Pond Dam D-2970 | Dam | 203 | Laurens | 34 28 48 N | 082 14 05 W |
| Zigzag Branch | Stream | | Hampton | 32 40 21 N | 081 08 06 W |
| Zimmerman Pond | Reservoir | 121 | Lexington | 33 52 50 N | 081 21 01 W |
| Zimmerman Pond | Reservoir | 212 | Spartanburg | 34 51 12 N | 081 53 37 W |
| Zion | Populated Place | 33 | Marion | 34 15 36 N | 079 19 04 W |
| Zion African Methodist Episcopal Church (historical) | Church | 169 | Lancaster | 34 43 02 N | 080 46 26 W |
| Zion Baptist Church | Church | 27 | Colleton | 32 57 34 N | 080 41 57 W |
| Zion Baptist Church | Church | 76 | Richland | 34 00 08 N | 081 02 28 W |
| Zion Baptist Church | Church | 52 | Sumter | 33 55 10 N | 080 20 49 W |
| Zion Branch Church | Church | 141 | Aiken | 33 28 40 N | 081 45 12 W |
| Zion Canaan Church | Church | 113 | Richland | 34 04 44 N | 080 58 34 W |
| Zion Cemetery | Cemetery | 27 | Berkeley | 33 21 40 N | 080 11 36 W |
| Zion Cemetery | Cemetery | 200 | Chester | 34 49 07 N | 081 13 51 W |
| Zion Cemetery | Cemetery | 175 | Chesterfield | 34 44 45 N | 080 21 31 W |
| Zion Cemetery | Cemetery | 27 | Colleton | 32 57 35 N | 080 41 57 W |
| Zion Cemetery | Cemetery | 110 | Lexington | 34 01 16 N | 081 09 12 W |
| Zion Cemetery | Cemetery | 131 | Newberry | 34 24 09 N | 081 38 48 W |
| Zion Cemetery | Cemetery | 156 | Newberry | 34 08 38 N | 081 31 47 W |