Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Almetta Church | Church | 119 | Chesterfield | 34 38 58 N | 080 23 01 W |
| Almwell Church | Church | 20 | Florence | 33 56 47 N | 079 33 26 W |
| Alston | Populated Place | 76 | Fairfield | 34 14 37 N | 081 19 00 W |
| Alston Creek | Stream | | Charleston | 32 55 37 N | 079 44 09 W |
| Alston Creek | Stream | | Charleston | 32 55 04 N | 079 45 33 W |
| Alston School | School | 30 | Dorchester | 33 01 53 N | 080 10 56 W |
| Alta Vista (subdivision) | Populated Place | 290 | Greenville | 34 50 02 N | 082 23 21 W |
| Althea (historical) | Populated Place | 110 | Lexington | 33 48 45 N | 081 27 49 W |
| Altman Branch | Stream | | Horry | 33 51 01 N | 079 04 53 W |
| Altman Pond | Lake | 103 | Lexington | 33 44 42 N | 081 23 42 W |
| Alverson Grove Church | Church | 305 | Spartanburg | 35 09 31 N | 081 59 06 W |
| Alverson Pond | Reservoir | 251 | Spartanburg | 34 53 12 N | 082 08 11 W |
| Alverson Pond Dam | Dam | 251 | Spartanburg | 34 53 12 N | 082 08 11 W |
| Alvin | Populated Place | 14 | Berkeley | 33 20 57 N | 079 48 58 W |
| Amada Church | Church | 30 | Florence | 34 05 51 N | 079 41 57 W |
| Amaker Pond | Reservoir | 63 | Orangeburg | 33 35 15 N | 081 00 13 W |
| Amaker School (historical) | School | 63 | Calhoun | 33 39 10 N | 080 38 29 W |
| Aman (historical) | Populated Place | 58 | Lee | 34 05 14 N | 080 19 59 W |
| Ambler School | School | 360 | Pickens | 34 57 27 N | 082 39 51 W |
| Amelia Lake | Reservoir | 85 | Aiken | 33 41 13 N | 081 18 41 W |
| Amelia Street Historic District | Park | 70 | Orangeburg | 33 29 40 N | 080 51 36 W |
| American Creative School | School | 90 | Lexington | 33 59 02 N | 081 04 31 W |
| American Legion Lake | Reservoir | 200 | Abbeville | 34 25 48 N | 082 20 53 W |
| American Legion Memorial Athletic Field | Park | 240 | Anderson | 34 29 40 N | 082 38 38 W |
| American Legion Stadium | Park | 44 | Florence | 34 12 25 N | 079 45 27 W |
| Amick Grove Church | Church | 153 | Saluda | 33 57 20 N | 081 38 17 W |
| Amicks Ferry (historical) | Crossing | 110 | Lexington | 34 04 58 N | 081 25 28 W |
| Amicks Pond | Reservoir | 134 | Saluda | 33 57 30 N | 081 38 05 W |
| Amicks Pond Dam D-1599 | Dam | 134 | Saluda | 33 57 30 N | 081 38 05 W |
| Ammons Cemetery | Cemetery | 24 | Marion | 34 08 04 N | 079 19 33 W |
| Anchorage Plantation | Locale | 8 | Charleston | 32 39 24 N | 080 08 53 W |
| Ancrum Ferry | Locale | 39 | Kershaw | 34 06 54 N | 080 36 59 W |
| Ancrum Swamp | Swamp | 4 | Berkeley | 33 00 08 N | 080 05 29 W |
| Andell Bridge | Bridge | 2 | Charleston | 32 36 32 N | 080 09 02 W |
| Anderson | Populated Place | 240 | Anderson | 34 30 12 N | 082 39 00 W |
| Anderson Army Air Field (historical) | Military (Historical) | 229 | Anderson | 34 29 40 N | 082 42 30 W |
| Anderson Branch | Stream | | Edgefield | 33 36 42 N | 082 01 25 W |
| Anderson Branch | Stream | | Orangeburg | 33 24 15 N | 080 52 10 W |
| Anderson Bridge | Bridge | 17 | Florence | 33 58 31 N | 079 40 55 W |
| Anderson Bridge | Bridge | 207 | Spartanburg | 34 47 50 N | 082 10 05 W |
| Anderson Bridge | Bridge | 195 | Spartanburg | 34 53 03 N | 082 00 39 W |
| Anderson Cemetery | Cemetery | 166 | Chester | 34 39 43 N | 081 00 36 W |
| Anderson Cemetery | Cemetery | 45 | Darlington | 34 10 52 N | 079 55 06 W |
| Anderson Cemetery | Cemetery | 22 | Horry | 33 59 01 N | 078 59 16 W |
| Anderson Chapel (historical) | Church | 8 | Horry | 33 53 38 N | 079 03 14 W |
| Anderson City Hall | Building | 234 | Anderson | 34 30 04 N | 082 38 58 W |
| Anderson College | School | 232 | Anderson | 34 30 49 N | 082 38 19 W |
| Anderson College Library | Building | 234 | Anderson | 34 30 50 N | 082 38 23 W |
| Anderson Country Club | Locale | 226 | Anderson | 34 29 50 N | 082 40 29 W |
| Anderson County | Civil | 237 | Anderson | 34 32 00 N | 082 38 59 W |
| Anderson County Airport | Airport | 230 | Anderson | 34 29 41 N | 082 42 31 W |
| Anderson County Courthouse | Building | 240 | Anderson | 34 30 12 N | 082 38 59 W |
| Anderson County Health Center | Building | 234 | Anderson | 34 30 07 N | 082 39 10 W |
| Anderson County Jail | Building | 242 | Anderson | 34 32 00 N | 082 40 59 W |
| Anderson County Library | Building | 242 | Anderson | 34 30 35 N | 082 38 58 W |
| Anderson Creek | Stream | | Charleston | 32 56 19 N | 079 36 49 W |
| Anderson Downtown Historic District | Park | 240 | Anderson | 34 30 13 N | 082 39 00 W |
| Anderson Ferry (historical) | Crossing | 118 | Greenwood | 34 09 45 N | 081 54 28 W |
| Anderson First Presbyterian Cemetery | Cemetery | 233 | Anderson | 34 30 15 N | 082 39 15 W |
| Anderson Gardens (subdivision) | Populated Place | 225 | Anderson | 34 29 20 N | 082 37 03 W |
| Anderson Lake | Lake | 14 | Marion | 34 11 56 N | 079 09 45 W |
| Anderson Lake | Reservoir | 110 | Aiken | 33 43 01 N | 081 31 53 W |
| Anderson Mall Shopping Center | Locale | 244 | Anderson | 34 32 22 N | 082 40 12 W |
| Anderson Memorial Gardens | Cemetery | 235 | Anderson | 34 30 18 N | 082 42 25 W |
| Anderson Memorial Hospital | Hospital | 236 | Anderson | 34 30 48 N | 082 38 47 W |
| Anderson Mennonite Church | Church | 240 | Anderson | 34 28 21 N | 082 39 46 W |
| Anderson Millpond | Lake | 79 | Aiken | 33 27 29 N | 081 43 55 W |
| Anderson Millpond | Reservoir | 94 | Aiken | 33 27 01 N | 081 43 59 W |
| Anderson Millpond | Reservoir | 28 | Marlboro | 34 41 31 N | 079 50 05 W |
| Anderson Plaza Shopping Center | Locale | 191 | Greenwood | 34 10 24 N | 082 09 16 W |
| Anderson Post Office | Post Office | 244 | Anderson | 34 30 30 N | 082 38 56 W |
| Anderson Primary School | School | 18 | Williamsburg | 33 40 19 N | 079 49 14 W |
| Anderson Quarry | Mine | 86 | Fairfield | 34 19 37 N | 081 14 06 W |
| Anderson Reservoir | Reservoir | 230 | Anderson | 34 37 18 N | 082 34 59 W |
| Anderson Road Plaza Shopping Center | Locale | 303 | Greenville | 34 48 55 N | 082 26 33 W |
| Anderson School | School | 22 | Berkeley | 33 14 57 N | 079 58 01 W |
| Anderson Speedway | Locale | 271 | Anderson | 34 39 39 N | 082 35 07 W |
| Anderson Village (subdivision) | Populated Place | 225 | Anderson | 34 33 00 N | 082 39 42 W |
| Andersons Bridge | Bridge | 183 | Spartanburg | 34 50 55 N | 082 04 01 W |
| Andersons Ferry (historical) | Crossing | 201 | Oconee | 34 38 21 N | 082 51 10 W |
| Andersons Mill (historical) | Locale | 135 | Laurens | 34 20 54 N | 082 06 02 W |
| Andersons Mill (historical) | Locale | 183 | Spartanburg | 34 50 58 N | 082 04 06 W |
| Andersons Millpond | Reservoir | 28 | Marlboro | 34 41 31 N | 079 50 07 W |
| Andersons Pond D-3059 Dam | Dam | 68 | Barnwell | 33 19 49 N | 081 26 53 W |
| Andersonville (historical) | Populated Place | 201 | Anderson | 34 26 50 N | 082 51 19 W |
| Andersonville Cemetery | Cemetery | 213 | Anderson | 34 29 02 N | 082 48 14 W |
| Andersonville Church | Church | 213 | Anderson | 34 29 02 N | 082 48 14 W |
| Andersonville Ferry (historical) | Crossing | 201 | Anderson | 34 26 46 N | 082 51 28 W |
| Andover (historical) | Populated Place | 312 | Spartanburg | 35 04 45 N | 082 12 20 W |
| Andrew Chapel | Church | 115 | Calhoun | 33 42 21 N | 080 57 22 W |
| Andrew Chapel | Church | 47 | Orangeburg | 33 28 02 N | 080 42 47 W |
| Andrew Chapel Methodist Church (historical) | Church | 188 | Greenwood | 34 18 07 N | 082 09 46 W |
| Andrew Jackson Academy | School | 44 | Bamberg | 33 11 13 N | 081 01 13 W |
| Andrew Jackson High School | School | 187 | Lancaster | 34 34 25 N | 080 36 42 W |
| Andrew Jackson Middle School | School | 181 | Lancaster | 34 34 23 N | 080 36 54 W |
| Andrew Jackson State Park | Park | 180 | Lancaster | 34 50 23 N | 080 48 18 W |
| Andrew Jackson State Park Lake | Reservoir | 151 | Lancaster | 34 50 43 N | 080 48 29 W |
| Andrew Pickens Ranger Station | Building | 508 | Oconee | 34 48 35 N | 083 07 40 W |
| Andrews | Populated Place | 8 | Williamsburg | 33 27 05 N | 079 33 39 W |
| Andrews Branch Library | Building | 9 | Georgetown | 33 27 06 N | 079 33 42 W |
| Andrews Cemeteries | Cemetery | 188 | Greenwood | 34 18 07 N | 082 09 50 W |
| Andrews Chapel | Church | 46 | Clarendon | 33 39 16 N | 080 23 03 W |
| Andrews Chapel | Church | 186 | Greenwood | 34 17 31 N | 082 10 41 W |
| Andrews Chapel | Church | 49 | Orangeburg | 33 28 48 N | 080 42 20 W |
| Andrews Chapel School (historical) | School | 188 | Greenwood | 34 17 29 N | 082 10 45 W |
| Andrews Colored School (historical) | School | 10 | Georgetown | 33 27 02 N | 079 34 05 W |
| Andrews Farms (subdivision) | Populated Place | 225 | Spartanburg | 34 56 24 N | 081 53 12 W |
| Andrews Field House | Building | 237 | Spartanburg | 34 57 33 N | 081 55 56 W |
| Andrews High School | School | 10 | Georgetown | 33 26 58 N | 079 34 07 W |
| Andrews Industrial Park | Locale | 7 | Georgetown | 33 26 51 N | 079 31 24 W |