Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Canaan School (historical) | School | 45 | Orangeburg | 33 19 56 N | 080 56 15 W |
| Canaan School (historical) | School | 153 | Union | 34 35 11 N | 081 39 51 W |
| Canaan United Methodist Church | Church | 6 | Dorchester | 32 57 50 N | 080 17 15 W |
| Canady Branch | Stream | | Berkeley | 33 14 26 N | 079 56 52 W |
| Canady Landing | Populated Place | 3 | Charleston | 32 48 56 N | 080 24 17 W |
| Canadys | Populated Place | 25 | Colleton | 33 03 21 N | 080 37 13 W |
| Canadys Bridge | Bridge | 18 | Dorchester | 33 03 53 N | 080 36 47 W |
| Canadys Cemetery | Cemetery | 25 | Colleton | 33 03 31 N | 080 37 05 W |
| Canadys Steam Electric Generating Plant | Building | 23 | Colleton | 33 03 54 N | 080 37 21 W |
| Canal Branch | Stream | | Chesterfield | 34 39 47 N | 080 24 48 W |
| Canal Branch | Stream | | Chesterfield | 34 39 56 N | 080 12 58 W |
| Canal Branch | Stream | | Chesterfield | 34 40 48 N | 080 22 08 W |
| Canal Branch | Stream | | Florence | 34 11 25 N | 079 40 36 W |
| Canal Industries Pond | Reservoir | 28 | Florence | 34 12 37 N | 079 38 41 W |
| Canal Industries Pond Dam | Reservoir | 34 | Marlboro | 34 23 19 N | 079 36 17 W |
| Canal Industries Pond Dam D-2950 | Dam | 34 | Marlboro | 34 23 19 N | 079 36 17 W |
| Canal Industries Pond Dam D-3561 | Dam | 28 | Florence | 34 12 37 N | 079 38 41 W |
| Canal Picnic Area | Locale | 15 | Berkeley | 33 16 22 N | 079 57 50 W |
| Candy Branch | Stream | | Abbeville | 34 04 09 N | 082 19 38 W |
| Candy Branch | Stream | | Orangeburg | 33 25 40 N | 080 31 58 W |
| Candys Chapel | Church | 140 | McCormick | 34 00 34 N | 082 26 14 W |
| Cane Bay | Basin | 24 | Berkeley | 33 15 12 N | 080 11 26 W |
| Cane Bay | Basin | 15 | Georgetown | 33 46 10 N | 079 20 03 W |
| Cane Bay | Stream | | Horry | 33 49 20 N | 078 52 01 W |
| Cane Bay | Swamp | 23 | Marion | 34 07 33 N | 079 19 19 W |
| Cane Bay School (historical) | School | 17 | Georgetown | 33 45 46 N | 079 19 08 W |
| Cane Brake | Populated Place | 274 | Greenville | 34 53 16 N | 082 15 37 W |
| Cane Brake Branch | Stream | | Laurens | 34 33 10 N | 081 41 29 W |
| Cane Brake School (historical) | School | 145 | Saluda | 33 59 48 N | 081 43 15 W |
| Cane Branch | Gut | 21 | Dillon | 34 19 19 N | 079 16 48 W |
| Cane Branch | Stream | | Berkeley | 33 09 50 N | 079 30 48 W |
| Cane Branch | Stream | | Dorchester | 33 10 44 N | 080 23 18 W |
| Cane Branch | Stream | | Florence | 34 09 10 N | 079 40 22 W |
| Cane Branch | Stream | | Horry | 34 00 26 N | 078 56 19 W |
| Cane Branch Church | Church | 27 | Horry | 34 00 12 N | 078 56 31 W |
| Cane Branch Church | Church | 18 | Williamsburg | 33 42 39 N | 079 50 42 W |
| Cane Branch Lookout Tower | Tower | 29 | Colleton | 32 50 57 N | 080 47 07 W |
| Cane Branch School (historical) | School | 18 | Colleton | 32 50 41 N | 080 46 19 W |
| Cane Branch School (historical) | School | 18 | Williamsburg | 33 42 39 N | 079 50 47 W |
| Cane Creek | Gut | 0 | Georgetown | 33 09 57 N | 079 15 30 W |
| Cane Creek | Stream | | Cherokee | 35 12 31 N | 081 48 07 W |
| Cane Creek | Stream | | Greenville | 34 54 35 N | 082 16 49 W |
| Cane Creek | Stream | | Lancaster | 34 41 45 N | 080 51 32 W |
| Cane Creek | Stream | | Laurens | 34 15 22 N | 082 00 56 W |
| Cane Creek | Stream | | Oconee | 34 43 51 N | 082 54 52 W |
| Cane Creek | Stream | | Pickens | 34 57 15 N | 082 54 31 W |
| Cane Creek | Stream | | Spartanburg | 34 42 48 N | 081 51 27 W |
| Cane Creek | Stream | | Union | 34 29 48 N | 081 26 26 W |
| Cane Creek Cemetery | Cemetery | 171 | Union | 34 38 11 N | 081 31 21 W |
| Cane Creek Cemetery | Cemetery | 153 | Union | 34 37 38 N | 081 32 47 W |
| Cane Creek Cemetery | Cemetery | 166 | Union | 34 36 32 N | 081 31 16 W |
| Cane Creek Church (historical) | Church | 37 | Allendale | 32 53 26 N | 081 24 30 W |
| Cane Creek Landing | Locale | 244 | Oconee | 34 44 06 N | 082 59 03 W |
| Cane Creek Presbyterian Church | Church | 170 | Union | 34 38 10 N | 081 31 20 W |
| Cane Creek School (historical) | School | 278 | Pickens | 34 56 57 N | 082 53 48 W |
| Cane Creek Watershed Site 16 | Reservoir | 177 | Lancaster | 34 46 19 N | 080 40 11 W |
| Cane Creek Watershed Site Seven | Reservoir | 163 | Lancaster | 34 46 49 N | 080 41 41 W |
| Cane Creek WCD Dam Number 18-A D-1786 | Dam | 165 | Lancaster | 34 44 07 N | 080 42 47 W |
| Cane Gall | Swamp | 28 | Hampton | 32 44 07 N | 081 06 37 W |
| Cane Gully Branch | Stream | | Berkeley | 33 13 12 N | 079 55 35 W |
| Cane Island | Island | 0 | Beaufort | 32 22 25 N | 080 39 58 W |
| Cane Island | Island | 28 | Chesterfield | 34 44 58 N | 079 54 17 W |
| Cane Island | Island | 12 | Dorchester | 33 03 51 N | 080 28 41 W |
| Cane Island | Island | 13 | Dorchester | 33 03 28 N | 080 30 08 W |
| Cane Island | Island | 1 | Georgetown | 33 09 37 N | 079 15 12 W |
| Cane Mountain | Summit | 755 | Pickens | 35 02 24 N | 082 50 25 W |
| Cane Patch (subdivision) | Populated Place | 7 | Horry | 33 44 28 N | 078 49 22 W |
| Cane Patch Swamp | Swamp | 10 | Horry | 33 45 52 N | 078 50 40 W |
| Cane Pond Branch | Stream | | Berkeley | 33 15 10 N | 079 54 18 W |
| Cane Savannah | Populated Place | 55 | Sumter | 33 54 07 N | 080 27 01 W |
| Cane Savannah Creek | Stream | | Sumter | 33 52 41 N | 080 21 28 W |
| Cane Savannah Raceway | Locale | 55 | Sumter | 33 54 13 N | 080 26 42 W |
| Cane Spring School (historical) | School | 225 | York | 35 01 48 N | 081 17 59 W |
| Cane Swamp | Swamp | 12 | Marion | 33 56 37 N | 079 25 08 W |
| Canebrake Branch | Stream | | Saluda | 34 01 13 N | 081 44 09 W |
| Canepatch Swash | Beach | 4 | Horry | 33 44 06 N | 078 49 34 W |
| Caney Branch | Stream | | Lancaster | 34 40 53 N | 080 41 13 W |
| Caney Branch | Stream | | Lexington | 33 58 41 N | 081 28 57 W |
| Caney Branch | Stream | | Oconee | 34 50 51 N | 082 54 07 W |
| Caney Branch | Stream | | Williamsburg | 33 42 25 N | 079 27 21 W |
| Caney Branch School | School | 27 | Colleton | 32 51 59 N | 080 45 44 W |
| Caney Branch School | School | 151 | Lexington | 33 57 32 N | 081 29 26 W |
| Caney Fork Creek | Stream | | Chester | 34 40 53 N | 081 16 01 W |
| Canfield Cemetery | Cemetery | 118 | McCormick | 33 53 00 N | 082 14 41 W |
| Cannan Church | Church | 4 | Colleton | 32 42 39 N | 080 42 45 W |
| Cannon Bridge | Bridge | 36 | Orangeburg | 33 18 51 N | 080 57 55 W |
| Cannon Cemetery | Cemetery | 47 | Darlington | 34 17 23 N | 079 52 57 W |
| Cannon Church | Church | 94 | Orangeburg | 33 37 59 N | 081 01 50 W |
| Cannon Creek | Stream | | Pickens | 34 52 01 N | 082 45 19 W |
| Cannon Creek Cemetery | Cemetery | 180 | Newberry | 34 15 19 N | 081 34 32 W |
| Cannon Hills | Populated Place | 283 | Greenville | 34 59 13 N | 082 15 11 W |
| Cannon Lake | Lake | 4 | Marion | 33 52 11 N | 079 16 12 W |
| Cannon Memorial Hospital | Hospital | 302 | Pickens | 34 52 28 N | 082 42 25 W |
| Cannon Memorial Park | Cemetery | 266 | Greenville | 34 42 08 N | 082 13 16 W |
| Cannon Mountain | Summit | 387 | Pickens | 34 53 02 N | 082 40 51 W |
| Cannon Mountain Church | Church | 349 | Pickens | 34 53 02 N | 082 40 34 W |
| Cannon Park | Park | 4 | Charleston | 32 46 60 N | 079 56 39 W |
| Cannon Pond | Reservoir | 168 | Laurens | 34 24 36 N | 081 53 35 W |
| Cannon Pond Dam D-2994 | Dam | 168 | Laurens | 34 24 36 N | 081 53 35 W |
| Cannon Street Baptist Church | Church | 6 | Charleston | 32 47 28 N | 079 56 37 W |
| Cannons Camp Ground | Populated Place | 253 | Spartanburg | 35 00 34 N | 081 51 39 W |
| Cannons Campground Church | Church | 248 | Spartanburg | 35 00 31 N | 081 51 35 W |
| Cannons Creek | Stream | | Newberry | 34 16 54 N | 081 20 44 W |
| Cannons Creek Cemetery | Cemetery | 134 | Newberry | 34 16 43 N | 081 32 14 W |
| Cannons Creek Church (historical) | Church | 142 | Newberry | 34 16 43 N | 081 32 10 W |
| Cannons Creek-Prosperity Church | Church | 179 | Newberry | 34 15 18 N | 081 34 34 W |
| Cannons Elementary School | School | 255 | Spartanburg | 35 00 43 N | 081 51 45 W |
| Cannons Mill (historical) | Locale | 25 | Horry | 34 02 14 N | 079 07 02 W |
| Canoe Creek | Stream | | Anderson | 34 16 04 N | 082 43 34 W |
| Canoe Creek | Stream | | Cherokee | 35 06 07 N | 081 34 23 W |