Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Ebenezer School | School | 162 | Kershaw | 34 28 04 N | 080 41 07 W |
| Ebenezer School | School | 56 | Lee | 34 15 33 N | 080 10 15 W |
| Ebenezer School | School | 99 | Orangeburg | 33 39 35 N | 081 02 32 W |
| Ebenezer School | School | 61 | Sumter | 34 00 59 N | 080 24 11 W |
| Ebenezer School (historical) | School | 207 | Anderson | 34 23 07 N | 082 34 03 W |
| Ebenezer School (historical) | School | 206 | Anderson | 34 23 56 N | 082 33 27 W |
| Ebenezer School (historical) | School | 243 | Anderson | 34 33 08 N | 082 43 10 W |
| Ebenezer School (historical) | School | 85 | Barnwell | 33 24 16 N | 081 18 14 W |
| Ebenezer School (historical) | School | 24 | Berkeley | 33 15 28 N | 080 19 30 W |
| Ebenezer School (historical) | School | 27 | Berkeley | 33 09 06 N | 080 03 35 W |
| Ebenezer School (historical) | School | 213 | Cherokee | 35 00 33 N | 081 35 47 W |
| Ebenezer School (historical) | School | 32 | Clarendon | 33 51 55 N | 080 04 27 W |
| Ebenezer School (historical) | School | 43 | Florence | 34 10 29 N | 079 51 08 W |
| Ebenezer School (historical) | School | 320 | Greenville | 35 05 18 N | 082 15 49 W |
| Ebenezer School (historical) | School | 140 | Kershaw | 34 25 12 N | 080 41 02 W |
| Ebenezer School (historical) | School | 58 | Marlboro | 34 43 56 N | 079 48 26 W |
| Ebenezer School (historical) | School | 39 | Marlboro | 34 34 41 N | 079 38 59 W |
| Ebenezer School (historical) | School | 170 | Union | 34 51 43 N | 081 34 02 W |
| Ebinport Elementary School | School | 195 | York | 34 58 08 N | 081 01 49 W |
| Eccles Cemetery | Cemetery | 9 | Berkeley | 33 07 13 N | 079 45 07 W |
| Eccles Church | Church | 7 | Berkeley | 33 07 13 N | 079 45 00 W |
| Echaw Creek | Stream | | Berkeley | 33 15 21 N | 079 32 50 W |
| Echee Pond | Lake | 42 | Allendale | 33 05 06 N | 081 32 16 W |
| Ed Dohar Pond | Reservoir | 232 | Laurens | 34 38 36 N | 082 10 53 W |
| Ed Dohar Pond Dam D-3007 | Dam | 232 | Laurens | 34 38 36 N | 082 10 53 W |
| Edding Creek | Stream | -3 | Beaufort | 32 27 01 N | 080 31 47 W |
| Edding Point | Cape | 2 | Beaufort | 32 27 01 N | 080 31 54 W |
| Edding Point School (historical) | School | 3 | Beaufort | 32 25 49 N | 080 33 33 W |
| Eddy Lake | Lake | 2 | Horry | 33 38 40 N | 079 07 32 W |
| Eddy Lake (historical) | Populated Place | 9 | Horry | 33 39 01 N | 079 07 14 W |
| Eden Church | Church | 48 | Bamberg | 33 15 08 N | 081 05 51 W |
| Eden Church | Church | 302 | Spartanburg | 35 09 00 N | 081 58 38 W |
| Eden Pond | Reservoir | 80 | Lexington | 33 56 07 N | 081 13 04 W |
| Eden Saltworks Creek | Stream | | Horry | 33 50 37 N | 078 36 17 W |
| Eden School (historical) | School | 57 | Bamberg | 33 16 58 N | 081 06 48 W |
| Eden Street School (historical) | School | 43 | Clarendon | 33 43 04 N | 080 17 10 W |
| Edenfield Park | Park | 55 | Aiken | 33 29 30 N | 081 58 01 W |
| Edens (historical) | Populated Place | 233 | Laurens | 34 34 32 N | 082 11 01 W |
| Edens Cemetery | Cemetery | 13 | Berkeley | 33 21 10 N | 079 49 09 W |
| Edens School (historical) | School | 235 | Laurens | 34 34 47 N | 082 11 09 W |
| Edens Small Pond | Reservoir | 30 | Calhoun | 33 46 07 N | 080 02 11 W |
| Edens Small Pond Dam D-2615 | Dam | 30 | Calhoun | 33 46 07 N | 080 02 11 W |
| Edenwood | Populated Place | 61 | Lexington | 33 57 14 N | 081 03 35 W |
| Edenwood Plaza Shopping Center | Locale | 49 | Lexington | 33 56 49 N | 081 04 38 W |
| Edgar A Brown Dam D-3064 | Dam | 54 | Barnwell | 33 14 49 N | 081 22 05 W |
| Edgar A Brown Lake | Reservoir | 54 | Barnwell | 33 14 49 N | 081 22 05 W |
| Edgefield | Populated Place | 162 | Edgefield | 33 47 22 N | 081 55 46 W |
| Edgefield County | Civil | 140 | Edgefield | 33 47 00 N | 081 57 59 W |
| Edgefield County Airport | Airport | 182 | Edgefield | 33 44 12 N | 081 49 10 W |
| Edgefield County Hospital | Hospital | 167 | Edgefield | 33 46 43 N | 081 55 48 W |
| Edgefield County Training School (historical) | School | 188 | Edgefield | 33 49 22 N | 081 47 57 W |
| Edgefield Heights (subdivision) | Populated Place | 119 | Aiken | 33 30 15 N | 081 57 22 W |
| Edgefield High School (historical) | School | 149 | Edgefield | 33 47 40 N | 081 55 40 W |
| Edgefield Historic District | Park | 160 | Edgefield | 33 47 22 N | 081 55 44 W |
| Edgemere | Populated Place | 198 | Greenwood | 34 13 23 N | 082 11 05 W |
| Edgemoor | Populated Place | 180 | Chester | 34 48 21 N | 081 00 41 W |
| Edgemoor Associate Reformed Presbyterian Church | Church | 182 | Chester | 34 48 14 N | 081 00 38 W |
| Edgemoor High School (historical) | School | 181 | Chester | 34 48 18 N | 081 00 34 W |
| Edgewater (subdivision) | Populated Place | 48 | Sumter | 33 55 15 N | 080 22 52 W |
| Edgewater Park | Populated Place | 4 | Charleston | 32 46 19 N | 080 00 05 W |
| Edgewood (subdivision) | Populated Place | 87 | Kershaw | 34 17 15 N | 080 36 49 W |
| Edgewood Baptist Church | Church | 25 | Colleton | 32 55 02 N | 080 40 43 W |
| Edgewood Cemetery | Cemetery | 183 | Greenwood | 34 12 28 N | 082 09 49 W |
| Edgewood Elementary School | School | 181 | York | 34 54 18 N | 081 02 17 W |
| Edgewood Middle School | School | 165 | Greenwood | 34 10 43 N | 082 01 11 W |
| Edgewood Park | Park | 164 | Abbeville | 34 05 59 N | 082 35 34 W |
| Edgewood School | School | 183 | Abbeville | 34 13 22 N | 082 25 58 W |
| Edgewood Square Shopping Center | Locale | 145 | Aiken | 33 31 26 N | 081 57 07 W |
| Edinburgh | Populated Place | 82 | Richland | 34 05 07 N | 080 56 54 W |
| Edings Island | Island | 1 | Charleston | 32 30 05 N | 080 18 10 W |
| Edingsville Beach | Beach | 2 | Charleston | 32 31 25 N | 080 15 49 W |
| Edisto | Populated Place | 67 | Orangeburg | 33 28 36 N | 080 53 55 W |
| Edisto Beach | Beach | 2 | Colleton | 32 29 14 N | 080 19 10 W |
| Edisto Beach | Populated Place | 2 | Colleton | 32 28 46 N | 080 20 05 W |
| Edisto Beach State Park | Park | 0 | Charleston | 32 30 21 N | 080 18 40 W |
| Edisto Church | Church | 100 | Aiken | 33 28 09 N | 081 24 18 W |
| Edisto Church | Church | 34 | Bamberg | 33 12 49 N | 080 52 15 W |
| Edisto Church | Church | 12 | Charleston | 32 34 45 N | 080 17 48 W |
| Edisto Church | Church | 12 | Colleton | 33 02 33 N | 080 26 15 W |
| Edisto Church | Church | 50 | Orangeburg | 33 22 32 N | 080 55 50 W |
| Edisto Club | Populated Place | 55 | Bamberg | 33 24 11 N | 081 09 22 W |
| Edisto Experimental Station | Locale | 98 | Barnwell | 33 21 52 N | 081 19 42 W |
| Edisto High School | School | 71 | Orangeburg | 33 26 07 N | 080 54 57 W |
| Edisto Island | Island | 7 | Charleston | 32 33 34 N | 080 17 42 W |
| Edisto Island | Populated Place | 2 | Charleston | 32 33 37 N | 080 16 47 W |
| Edisto Island Church | Church | 11 | Charleston | 32 34 48 N | 080 18 30 W |
| Edisto Island Library | Building | 7 | Charleston | 32 34 23 N | 080 17 09 W |
| Edisto Island School | School | 7 | Charleston | 32 34 23 N | 080 17 09 W |
| Edisto Lake | Reservoir | 95 | Aiken | 33 40 49 N | 081 19 17 W |
| Edisto Middle School | School | 56 | Orangeburg | 33 23 43 N | 080 57 25 W |
| Edisto Plant Basin Dam D-2147 | Dam | 98 | Aiken | 33 39 13 N | 081 34 11 W |
| Edisto Plant Settling Basin Hube | Reservoir | 98 | Aiken | 33 39 13 N | 081 34 11 W |
| Edisto Pond | Reservoir | 60 | Bamberg | 33 21 37 N | 081 05 59 W |
| Edisto Pond Dam D-2810 | Dam | 60 | Bamberg | 33 21 37 N | 081 05 59 W |
| Edisto Pond Dam D-3061 | Dam | 87 | Barnwell | 33 21 07 N | 081 18 41 W |
| Edisto Primary School | School | 77 | Orangeburg | 33 26 09 N | 080 55 22 W |
| Edisto River | Stream | | Charleston | 32 39 16 N | 080 23 17 W |
| Edisto Sand Pit | Mine | 2 | Charleston | 32 45 32 N | 080 26 14 W |
| Edisto School | School | 31 | Colleton | 33 08 06 N | 080 44 23 W |
| Edisto School (historical) | School | 102 | Aiken | 33 28 12 N | 081 24 18 W |
| Edisto School (historical) | School | 36 | Bamberg | 33 12 29 N | 080 52 54 W |
| Edisto School (historical) | School | 36 | Orangeburg | 33 17 59 N | 080 53 58 W |
| Edisto Village Shopping Center | Locale | 51 | Orangeburg | 33 28 58 N | 080 52 04 W |
| Edistone (historical) | Populated Place | 57 | Orangeburg | 33 28 06 N | 080 53 03 W |
| Edith L Frierson Elementary School | School | 10 | Charleston | 32 38 24 N | 080 10 58 W |
| Edmund | Populated Place | 142 | Lexington | 33 51 42 N | 081 12 00 W |
| Edmund A Burns Elementary School | School | 11 | Charleston | 32 51 13 N | 079 59 28 W |
| Edmund School (historical) | School | 142 | Lexington | 33 51 37 N | 081 12 01 W |
| Edmund School (historical) | School | 143 | Lexington | 33 51 21 N | 081 12 08 W |
| Edmunds High School | School | 52 | Sumter | 33 55 39 N | 080 21 13 W |