Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Ashley Retreat | Populated Place | 8 | Dorchester | 32 57 59 N | 080 14 42 W |
| Ashley River | Stream | | Charleston | 32 45 46 N | 079 55 44 W |
| Ashley River Baptist Church | Church | 4 | Charleston | 32 46 57 N | 079 59 33 W |
| Ashley River Church | Church | 13 | Dorchester | 32 56 03 N | 080 10 35 W |
| Ashley River Elementary School | School | 7 | Charleston | 32 48 03 N | 080 01 20 W |
| Ashley River Memorial Bridge | Bridge | 7 | Charleston | 32 47 01 N | 079 57 41 W |
| Ashley Shores (subdivision) | Populated Place | 6 | Charleston | 32 50 41 N | 079 59 32 W |
| Ashley Villas (subdivision) | Populated Place | 8 | Charleston | 32 51 34 N | 080 03 08 W |
| Ashleyville | Populated Place | 5 | Charleston | 32 47 36 N | 079 59 04 W |
| Ashmore Store (historical) | Locale | 261 | Greenville | 34 40 33 N | 082 15 26 W |
| Ashpole Swamp | Swamp | 19 | Dillon | 34 19 30 N | 079 06 23 W |
| Ashton | Populated Place | 35 | Colleton | 33 00 58 N | 080 58 14 W |
| Ashton Branch | Stream | | Colleton | 33 02 03 N | 080 57 52 W |
| Ashton Cemetery | Cemetery | 32 | Colleton | 33 01 18 N | 080 58 30 W |
| Ashton Church | Church | 32 | Colleton | 33 01 18 N | 080 58 30 W |
| Ashton School (historical) | School | 33 | Colleton | 33 01 07 N | 080 58 31 W |
| Ashwood | Populated Place | 58 | Lee | 34 06 33 N | 080 18 59 W |
| Ashwood Church | Church | 68 | Lee | 34 07 17 N | 080 20 36 W |
| Ashwood Estates | Populated Place | 34 | Florence | 34 07 41 N | 079 46 27 W |
| Ashwood Lake | Reservoir | 53 | Lee | 34 06 06 N | 080 18 57 W |
| Ashwood Raceway | Locale | 65 | Lee | 34 08 12 N | 080 19 06 W |
| Ashwood School (historical) | School | 58 | Lee | 34 06 29 N | 080 18 56 W |
| Ashworth Creek | Stream | | Cherokee | 35 13 07 N | 081 43 37 W |
| Asias Branch | Stream | | Newberry | 34 25 40 N | 081 36 34 W |
| Askew Cemetery | Cemetery | 170 | Union | 34 51 50 N | 081 36 23 W |
| Askins Pond | Reservoir | 18 | Florence | 33 48 43 N | 079 41 59 W |
| Askins Pond Dam D-3574 | Dam | 18 | Florence | 33 48 43 N | 079 41 59 W |
| Aspen Heights | Populated Place | 166 | Greenwood | 34 12 54 N | 082 06 49 W |
| Assembly Acres Camp Lake | Reservoir | 197 | Greenville | 34 31 48 N | 082 22 35 W |
| Assembly Acres Camp Lake Dam D-2881 | Dam | 197 | Greenville | 34 31 48 N | 082 22 35 W |
| Assembly Apostolic Church | Church | 224 | Anderson | 34 30 11 N | 082 37 46 W |
| Assembly of God Church | Church | 182 | Laurens | 34 25 10 N | 081 48 52 W |
| Assembly of God Church | Church | 125 | Lexington | 33 56 42 N | 081 14 11 W |
| Assembly of God Church (historical) | Church | 251 | Cherokee | 35 10 17 N | 081 37 45 W |
| Assembly of the Lord Church | Church | 46 | Aiken | 33 18 34 N | 081 48 24 W |
| Atalaya Mansion | Building | 1 | Georgetown | 33 30 10 N | 079 04 07 W |
| Atchison Chapel | Church | 249 | Spartanburg | 34 54 44 N | 081 59 20 W |
| Atchison Creek | Gut | 1 | Georgetown | 33 10 12 N | 079 19 31 W |
| Athelone Heights | Populated Place | 292 | Greenville | 34 46 55 N | 082 23 42 W |
| Athens Church | Church | 146 | Lexington | 33 47 06 N | 081 05 59 W |
| Athens Church (historical) | Church | 21 | Horry | 34 06 31 N | 079 05 08 W |
| Athens School | School | 22 | Horry | 34 06 07 N | 079 05 41 W |
| Athens School (historical) | School | 146 | Lexington | 33 47 05 N | 081 05 58 W |
| Athens School (historical) | School | 132 | Lexington | 33 46 25 N | 081 05 55 W |
| Atkins | Populated Place | 47 | Lee | 34 02 17 N | 080 06 55 W |
| Atkins Drainage Canal | Canal | 49 | Lee | 34 04 17 N | 080 08 21 W |
| Atkinson Branch | Stream | | Horry | 33 51 42 N | 079 14 21 W |
| Atkinson Invst Pond Dam D-3545 | Dam | 42 | Darlington | 34 18 07 N | 079 48 29 W |
| Atkinson Pond D-0228 Dam | Dam | 157 | Chester | 34 43 31 N | 081 08 41 W |
| Atlantic Beach | Populated Place | 9 | Horry | 33 48 10 N | 078 42 59 W |
| Atlantic Beach Town Hall | Building | 9 | Horry | 33 48 19 N | 078 43 06 W |
| Atlas Road School | School | 45 | Richland | 33 56 34 N | 080 58 30 W |
| Attaway | Populated Place | 6 | Beaufort | 32 28 04 N | 080 37 48 W |
| Atteza Church | Church | 3 | Beaufort | 32 28 55 N | 080 35 04 W |
| Auburn | Populated Place | 59 | Darlington | 34 22 32 N | 079 58 33 W |
| Auburn School (historical) | School | 58 | Darlington | 34 22 22 N | 079 58 12 W |
| Audubon Homes | Populated Place | 127 | Aiken | 33 31 12 N | 081 56 04 W |
| Audubon Park | Populated Place | 53 | Sumter | 33 55 38 N | 080 23 01 W |
| Augsburg Evangelical Lutheran Church | Church | 189 | Union | 34 42 36 N | 081 37 12 W |
| August Hill | Summit | 347 | Spartanburg | 35 08 24 N | 082 05 00 W |
| August Pond | Reservoir | 248 | Greenville | 34 34 42 N | 082 24 29 W |
| August Pond Dam D-2861 | Dam | 248 | Greenville | 34 34 42 N | 082 24 29 W |
| Augusta Acres | Populated Place | 276 | Greenville | 34 46 52 N | 082 21 46 W |
| Augusta Circle Elementary School | School | 301 | Greenville | 34 49 15 N | 082 23 39 W |
| Augusta City Lock and Dam | Dam | 47 | Edgefield | 33 33 15 N | 082 02 14 W |
| Augusta Fields | Populated Place | 184 | Greenwood | 34 08 35 N | 082 08 15 W |
| Augusta Road Church | Church | 274 | Greenville | 34 43 31 N | 082 23 07 W |
| Augusta Road Park | Park | 303 | Greenville | 34 48 46 N | 082 23 02 W |
| Augusta Street Presbyterian Church | Church | 307 | Greenville | 34 50 11 N | 082 24 18 W |
| Augusta Street Presbyterian Church | Church | 64 | Lexington | 33 59 26 N | 081 03 37 W |
| Augusta View Heights | Populated Place | 98 | Aiken | 33 30 24 N | 081 55 11 W |
| Auld Brass Plantation | Locale | 3 | Beaufort | 32 40 51 N | 080 48 42 W |
| Austin (historical) | Populated Place | 198 | Laurens | 34 28 40 N | 082 09 49 W |
| Austin Acres | Populated Place | 55 | Sumter | 33 54 36 N | 080 25 26 W |
| Autumn Oaks | Populated Place | 241 | Anderson | 34 32 36 N | 082 37 30 W |
| Aveleigh Cemetery | Cemetery | 167 | Newberry | 34 17 02 N | 081 35 55 W |
| Aveleigh Presbyterian Church | Church | 155 | Newberry | 34 16 37 N | 081 36 56 W |
| Avenue of Oaks | Populated Place | 11 | Dorchester | 32 57 51 N | 080 08 50 W |
| Averill | Populated Place | 42 | Allendale | 33 04 28 N | 081 30 48 W |
| Avery Ford | Crossing | 88 | Union | 34 26 41 N | 081 32 24 W |
| Averys Ferry (historical) | Crossing | 201 | Anderson | 34 28 56 N | 082 57 39 W |
| Avian Park (subdivision) | Populated Place | 2 | Charleston | 32 47 52 N | 079 51 21 W |
| Aviation Square Shopping Center | Locale | 11 | Charleston | 32 54 24 N | 080 01 28 W |
| Avondale | Populated Place | 4 | Charleston | 32 47 18 N | 079 59 23 W |
| Avondale | Populated Place | 266 | Oconee | 34 42 57 N | 083 00 51 W |
| Avondale | Populated Place | 52 | Sumter | 33 54 41 N | 080 24 21 W |
| Avondale (subdivision) | Populated Place | 183 | Greenwood | 34 13 18 N | 082 08 46 W |
| Avondale Heights (subdivision) | Populated Place | 320 | Pickens | 34 49 25 N | 082 35 09 W |
| Avondale Terrace (subdivision) | Populated Place | 184 | York | 34 57 48 N | 081 00 59 W |
| Awanita Lake | Reservoir | 398 | Greenville | 35 08 07 N | 082 29 30 W |
| Awanita Lake Dam D-2215 | Dam | 388 | Greenville | 35 07 12 N | 082 29 29 W |
| Awendaw | Populated Place | 6 | Charleston | 33 02 16 N | 079 36 47 W |
| Awendaw Chapel (historical) | Church | 6 | Charleston | 33 02 13 N | 079 37 04 W |
| Awendaw Church | Church | 6 | Charleston | 32 58 51 N | 079 39 37 W |
| Awendaw Church | Church | 5 | Charleston | 33 01 41 N | 079 37 37 W |
| Awendaw Creek | Stream | | Charleston | 33 02 01 N | 079 31 57 W |
| Awendaw School | School | 6 | Charleston | 32 59 23 N | 079 38 37 W |
| Aycock Pond Dam D-3667 | Dam | 199 | York | 34 52 12 N | 081 14 29 W |
| Ayers (historical) | Populated Place | 45 | Marlboro | 34 36 39 N | 079 42 09 W |
| Aynor | Populated Place | 31 | Horry | 33 59 60 N | 079 11 58 W |
| Aynor High School | School | 31 | Horry | 33 59 60 N | 079 12 28 W |
| Aynor School (historical) | School | 25 | Horry | 33 59 29 N | 079 12 13 W |
| Azalea Estates (subdivision) | Populated Place | 25 | Dorchester | 33 02 28 N | 080 12 04 W |
| Azalea Sands Golf Course | Locale | 7 | Horry | 33 48 54 N | 078 42 44 W |
| Azalea Trailer Park | Populated Place | 55 | Sumter | 33 58 09 N | 080 23 25 W |
| B A Gary Middle School | School | 45 | Darlington | 34 17 23 N | 079 52 20 W |
| B B Dunn Pond Dam D-3027 | Dam | 166 | Abbeville | 34 13 24 N | 082 40 53 W |
| B D Lee Elementary School | School | 229 | Cherokee | 35 04 39 N | 081 39 42 W |
| B Workman Pond | Reservoir | 241 | Spartanburg | 34 48 12 N | 082 07 05 W |
| B'nai Israel Center | Church | 224 | Spartanburg | 34 57 30 N | 081 54 41 W |