Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Fosters Bay | Swamp | 24 | Colleton | 32 59 08 N | 080 45 45 W |
| Fosters Branch | Stream | | Newberry | 34 24 31 N | 081 30 26 W |
| Fosters Chapel | Church | 202 | Union | 34 49 37 N | 081 35 04 W |
| Fosters Chapel | Church | 205 | Union | 34 50 35 N | 081 41 20 W |
| Fosters Crossroads | Populated Place | 190 | Lancaster | 34 47 12 N | 080 50 28 W |
| Fosters Grove | Populated Place | 264 | Spartanburg | 35 03 46 N | 081 53 49 W |
| Fosters Landing | Locale | 6 | Berkeley | 33 15 15 N | 079 32 48 W |
| Fosters Mill (historical) | Locale | 118 | Union | 34 35 37 N | 081 50 13 W |
| Fosters School | School | 205 | Union | 34 49 46 N | 081 40 57 W |
| Foulk Cemetery | Cemetery | 160 | Saluda | 33 57 13 N | 081 34 35 W |
| Foundation Church | Church | 213 | York | 34 55 14 N | 080 55 35 W |
| Foundation School (historical) | School | 209 | York | 34 55 13 N | 080 55 37 W |
| Fountain Academy (historical) | School | 149 | Aiken | 33 38 04 N | 081 39 29 W |
| Fountain Branch | Stream | | Darlington | 34 19 16 N | 079 44 31 W |
| Fountain Branch (historical) | Stream | | Berkeley | 33 17 41 N | 080 01 14 W |
| Fountain Inn | Populated Place | 264 | Greenville | 34 41 20 N | 082 11 44 W |
| Fountain Inn Elementary School | School | 265 | Greenville | 34 41 45 N | 082 12 13 W |
| Fountain Inn Municipal Cemetery | Cemetery | 260 | Greenville | 34 41 30 N | 082 11 34 W |
| Fountain Lake | Populated Place | 26 | Orangeburg | 33 25 03 N | 080 19 35 W |
| Four Bridges Cemetery | Cemetery | 55 | Sumter | 33 59 07 N | 080 24 56 W |
| Four Bridges Church | Church | 55 | Sumter | 33 59 07 N | 080 24 56 W |
| Four Bridges School (historical) | School | 56 | Sumter | 33 59 06 N | 080 24 57 W |
| Four Corners | Locale | 6 | Charleston | 32 46 35 N | 079 55 51 W |
| Four County State Fish Hatchery | Locale | 169 | Newberry | 34 16 13 N | 081 34 51 W |
| Four H Club Dam D-3040 | Dam | 155 | Abbeville | 34 05 30 N | 082 21 41 W |
| Four H Club Lake | Reservoir | 155 | Abbeville | 34 05 30 N | 082 21 41 W |
| Four Hole Bridge | Bridge | 12 | Dorchester | 33 08 30 N | 080 20 54 W |
| Four Hole Bridge Revolutionary Post | Locale | 13 | Dorchester | 33 08 28 N | 080 20 52 W |
| Four Hole School | School | 48 | Orangeburg | 33 29 25 N | 080 43 08 W |
| Four Hole School (historical) | School | 18 | Berkeley | 33 10 16 N | 080 17 05 W |
| Four Hole Special Church | Church | 18 | Dorchester | 33 03 40 N | 080 22 30 W |
| Four Hole Swamp | Stream | | Dorchester | 33 03 05 N | 080 24 15 W |
| Four Holes | Populated Place | 23 | Orangeburg | 33 16 43 N | 080 25 59 W |
| Four Holes Church | Church | 50 | Orangeburg | 33 29 23 N | 080 43 17 W |
| Four Mile Branch School (historical) | School | 48 | Chesterfield | 34 44 10 N | 079 56 10 W |
| Four Mile Church (historical) | Church | 37 | Barnwell | 33 11 19 N | 081 43 23 W |
| Four Mile Creek | Stream | | Georgetown | 33 26 28 N | 079 15 03 W |
| Four Mile Creek | Stream | | York | 34 56 36 N | 080 53 54 W |
| Four Mile Reach | Channel | 57 | Edgefield | 33 34 33 N | 082 04 11 W |
| Four Mile School (historical) | School | 45 | Barnwell | 33 11 46 N | 081 42 49 W |
| Four Mile School (historical) | School | 5 | Charleston | 32 49 31 N | 079 50 25 W |
| Four Mile School (historical) | School | 5 | Charleston | 32 49 03 N | 079 50 04 W |
| Four Mile School (historical) | School | 11 | Horry | 33 52 23 N | 079 06 15 W |
| Four Pines School | School | 108 | Orangeburg | 33 33 46 N | 081 10 36 W |
| Four Seasons | Populated Place | 83 | Kershaw | 34 12 12 N | 080 43 24 W |
| Fourmile Branch | Stream | | Barnwell | 33 08 53 N | 081 44 59 W |
| Fourmile Branch | Stream | | Spartanburg | 34 56 27 N | 081 50 29 W |
| Fourmile Church | Church | 122 | Aiken | 33 24 49 N | 081 40 38 W |
| Fourmile Creek | Stream | | Orangeburg | 33 30 10 N | 080 54 17 W |
| Fourmile Creek | Stream | | Pickens | 34 47 27 N | 082 52 24 W |
| Fourmile Creek Canal | Canal | 10 | Georgetown | 33 09 46 N | 079 18 49 W |
| Fourmile Swamp | Stream | | Horry | 33 51 58 N | 079 06 03 W |
| Fourmile Swamp | Swamp | 6 | Jasper | 32 20 44 N | 081 04 47 W |
| Foursquare Gospel Church | Church | 221 | Cherokee | 35 04 26 N | 081 37 59 W |
| Fourteenmile Creek | Stream | | Lexington | 34 01 38 N | 081 09 54 W |
| Fourth Creek | Stream | | Lexington | 33 44 08 N | 081 06 19 W |
| Fourth of July Branch | Stream | | Berkeley | 33 10 16 N | 079 47 13 W |
| Fourth Presbyterian Church | Church | 303 | Greenville | 34 50 56 N | 082 23 29 W |
| Fourth Street Baptist Church | Church | 64 | Darlington | 34 22 15 N | 080 04 04 W |
| Fourty Acre Rock | Summit | 183 | Lancaster | 34 40 08 N | 080 31 37 W |
| Fouts Cemetery | Cemetery | 161 | Saluda | 33 57 49 N | 081 34 59 W |
| Fowl Craw Lake | Lake | 6 | Hampton | 32 35 41 N | 081 22 29 W |
| Fowler | Populated Place | 23 | Williamsburg | 33 42 10 N | 079 41 48 W |
| Fowler Branch | Stream | | Marion | 34 10 36 N | 079 14 37 W |
| Fowler Cemetery | Cemetery | 9 | Berkeley | 33 01 30 N | 079 45 20 W |
| Fowler Cemetery | Cemetery | 27 | Horry | 34 07 24 N | 078 53 25 W |
| Fowler School | School | 16 | Williamsburg | 33 43 26 N | 079 41 36 W |
| Fowler School (historical) | School | 32 | Horry | 34 08 01 N | 078 53 43 W |
| Fowlers Second Pond Dam D-3607 | Dam | 24 | Dillon | 34 16 49 N | 079 16 29 W |
| Fowlers Third Pond Dam D-3606 | Dam | 25 | Dillon | 34 16 43 N | 079 16 29 W |
| Fowles Pond | Reservoir | 113 | Lexington | 33 51 19 N | 081 20 41 W |
| Fox Bank (historical) | Populated Place | 22 | Berkeley | 33 07 09 N | 080 03 39 W |
| Fox Bay | Swamp | 33 | Horry | 34 04 01 N | 078 53 05 W |
| Fox Bay | Swamp | 27 | Marion | 34 08 54 N | 079 16 30 W |
| Fox Bay | Swamp | 26 | Marion | 34 13 58 N | 079 09 59 W |
| Fox Branch | Stream | | Chesterfield | 34 38 05 N | 080 17 59 W |
| Fox Branch | Stream | | Horry | 33 57 19 N | 078 56 21 W |
| Fox Branch Cemetery | Cemetery | 15 | Horry | 33 57 28 N | 078 56 47 W |
| Fox Creek | Stream | | Aiken | 33 31 59 N | 082 00 38 W |
| Fox Creek | Stream | | Fairfield | 34 23 59 N | 080 49 32 W |
| Fox Gully Branch | Stream | | Berkeley | 33 08 03 N | 079 48 05 W |
| Fox Hollow (subdivision) | Populated Place | 81 | Darlington | 34 23 41 N | 080 06 09 W |
| Fox Hunt | Populated Place | 246 | Spartanburg | 34 54 37 N | 082 01 13 W |
| Fox Lake | Lake | 3 | Jasper | 32 20 45 N | 081 08 04 W |
| Fox Mill (historical) | Locale | 42 | Aiken | 33 28 41 N | 081 56 24 W |
| Fox Pond | Swamp | 6 | Jasper | 32 17 18 N | 081 01 53 W |
| Fox Run (subdivision) | Populated Place | 282 | Oconee | 34 42 25 N | 082 55 53 W |
| Fox Run Country Club | Locale | 255 | Greenville | 34 44 25 N | 082 12 20 W |
| Fox Squirrel Ridge | Ridge | 322 | Pickens | 34 55 53 N | 082 41 44 W |
| Fox Swamp | Stream | | Berkeley | 33 19 24 N | 079 55 11 W |
| Fox Swamp Canal | Canal | 30 | Dillon | 34 23 42 N | 079 21 43 W |
| Fox Tindal Pond | Reservoir | 44 | Clarendon | 33 39 13 N | 080 26 35 W |
| Fox Valley | Populated Place | 232 | Anderson | 34 31 52 N | 082 36 11 W |
| Foxborough (subdivision) | Populated Place | 18 | Berkeley | 33 01 21 N | 080 03 01 W |
| Foxchase | Populated Place | 148 | Aiken | 33 32 00 N | 081 45 37 W |
| Foxcroft | Populated Place | 41 | Florence | 34 12 21 N | 079 50 38 W |
| Foxcroft | Populated Place | 304 | Greenville | 34 52 00 N | 082 18 07 W |
| Foxhall (subdivision) | Populated Place | 73 | Richland | 34 02 01 N | 080 59 15 W |
| Foxtown | Populated Place | 148 | Aiken | 33 42 48 N | 081 34 10 W |
| Foxville | Populated Place | 37 | Sumter | 33 53 10 N | 080 33 21 W |
| Foxville Crossroads | Populated Place | 232 | Abbeville | 34 23 22 N | 082 21 31 W |
| Foxville School (historical) | School | 232 | Abbeville | 34 23 05 N | 082 21 17 W |
| Foyster Creek | Stream | | Greenville | 35 01 36 N | 082 16 15 W |
| Frampton Inlet | Gut | 1 | Charleston | 32 31 53 N | 080 14 51 W |
| Fran Bridge (historical) | Bridge | 97 | Kershaw | 34 35 31 N | 080 23 00 W |
| Frances Chapel | Church | 67 | Chesterfield | 34 34 44 N | 080 01 51 W |
| Frances Mack Elementary School | School | 152 | Lexington | 33 49 13 N | 081 06 14 W |
| Francis Brown African Methodist Episcopal Church | Church | 5 | Charleston | 32 47 31 N | 079 56 44 W |
| Francis Cyril Jones Bridge | Bridge | 102 | Lexington | 33 48 08 N | 081 29 00 W |
| Francis Marion Bridge | Bridge | 23 | Clarendon | 33 30 35 N | 080 26 53 W |