Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Enon School | School | 273 | Macon | 36 34 49 N | 085 54 19 W |
| Enon Spring Missionary Baptist Church | Church | 78 | Shelby | 35 03 50 N | 090 04 59 W |
| Ensley | Locale | 69 | Shelby | 35 04 08 N | 090 07 15 W |
| Ensley Plantation | Locale | 65 | Shelby | 35 04 00 N | 090 10 15 W |
| Ensley Revetment | Levee | 58 | Shelby | 35 02 52 N | 090 10 57 W |
| Ensor | Populated Place | 323 | Putnam | 36 10 04 N | 085 39 28 W |
| Ensor Church | Church | 166 | Jackson | 36 19 12 N | 085 49 30 W |
| Ensor Hollow | Valley | | Putnam | 36 12 45 N | 085 46 14 W |
| Ensor Hollow Branch | Stream | | Putnam | 36 12 51 N | 085 46 17 W |
| Ensor Park (subdivision) | Populated Place | 331 | Putnam | 36 08 52 N | 085 30 17 W |
| Ensor School (historical) | School | 294 | Putnam | 36 06 31 N | 085 37 56 W |
| Ensworth School | School | 159 | Davidson | 36 07 28 N | 086 50 24 W |
| Enterprise | Populated Place | 380 | Hawkins | 36 20 46 N | 082 55 43 W |
| Enterprise | Populated Place | 233 | Maury | 35 28 18 N | 087 10 46 W |
| Enterprise Church | Church | 353 | Hamblen | 36 09 00 N | 083 14 31 W |
| Enterprise Church | Church | 451 | Sullivan | 36 28 16 N | 082 19 26 W |
| Enterprise School (historical) | School | 117 | Gibson | 35 50 41 N | 088 56 34 W |
| Enterprise School (historical) | School | 337 | Hamblen | 36 08 23 N | 083 14 42 W |
| Enterprise School (historical) | School | 377 | Hawkins | 36 20 44 N | 082 55 44 W |
| Enterprise School (historical) | School | 239 | Maury | 35 28 02 N | 087 10 38 W |
| Enterprise School (historical) | School | 451 | Sullivan | 36 28 16 N | 082 19 26 W |
| Enterprise United Methodist Church | Church | 240 | Maury | 35 28 00 N | 087 10 37 W |
| Enville | Populated Place | 128 | Chester | 35 23 05 N | 088 25 39 W |
| Enville Church | Church | 174 | Chester | 35 24 21 N | 088 26 45 W |
| Enville School (historical) | School | 128 | Chester | 35 23 00 N | 088 25 58 W |
| Eoff Branch | Stream | | Coffee | 35 27 25 N | 086 11 53 W |
| Ephesian Primitive Baptist Church | Church | 131 | Davidson | 36 10 21 N | 086 48 38 W |
| Ephesus | Populated Place | 135 | Carroll | 36 07 49 N | 088 17 19 W |
| Ephesus Baptist Church | Church | 137 | Carroll | 36 07 49 N | 088 17 25 W |
| Ephesus Cemetery | Cemetery | 140 | Carroll | 36 07 48 N | 088 17 28 W |
| Ephesus Church | Church | 220 | Giles | 35 06 43 N | 086 57 43 W |
| Ephesus Church | Church | 226 | Maury | 35 32 41 N | 087 01 04 W |
| Ephesus School (historical) | School | 141 | Carroll | 36 07 48 N | 088 17 31 W |
| Ephraim Bales Place | Locale | 700 | Sevier | 35 41 47 N | 083 28 11 W |
| Episcopal Church of the Advent (historical) | Church | 146 | Davidson | 36 09 39 N | 086 46 53 W |
| Episcopal Church of the Good Shepherd | Church | 579 | Hamilton | 34 59 43 N | 085 21 04 W |
| Episcopal Church of the Holy Trinity | Church | 86 | Shelby | 35 05 34 N | 089 56 13 W |
| Episcopal Church of the Redeemer | Church | 225 | Bedford | 35 29 06 N | 086 27 30 W |
| Epison Hollow | Valley | | Hickman | 35 53 12 N | 087 40 22 W |
| Epperson | Populated Place | 505 | Monroe | 35 15 27 N | 084 20 15 W |
| Epperson Cemetery | Cemetery | 420 | Claiborne | 36 22 59 N | 083 30 31 W |
| Epperson Cemetery | Cemetery | 386 | Grainger | 36 24 00 N | 083 25 22 W |
| Epperson Creek | Stream | | Crockett | 35 51 12 N | 089 06 37 W |
| Epperson Hospital | Hospital | 292 | McMinn | 35 26 24 N | 084 36 23 W |
| Epperson School (historical) | School | 506 | Monroe | 35 15 28 N | 084 20 16 W |
| Epps Hills | Summit | 349 | Rutherford | 35 36 54 N | 086 23 51 W |
| Epps Hollow | Valley | | Lincoln | 35 12 13 N | 086 40 48 W |
| Epps Hollow | Valley | | Lincoln | 35 15 50 N | 086 33 46 W |
| Epson Spring | Spring | 411 | Hawkins | 36 28 53 N | 082 59 47 W |
| Epworth | Populated Place | 201 | Williamson | 35 52 25 N | 086 47 30 W |
| Epworth Church | Church | 75 | Shelby | 35 09 21 N | 090 01 16 W |
| Epworth Church | Church | 201 | Williamson | 35 52 27 N | 086 47 31 W |
| Erasmus | Populated Place | 490 | Cumberland | 35 53 13 N | 085 11 06 W |
| Erie | Populated Place | 280 | Loudon | 35 38 51 N | 084 34 29 W |
| Erie Church | Church | 276 | Roane | 35 38 49 N | 084 35 49 W |
| Erin | Populated Place | 137 | Houston | 36 19 06 N | 087 41 41 W |
| Erin Branch | Stream | | Houston | 36 19 17 N | 087 40 25 W |
| Erin Cemetery | Cemetery | 188 | Houston | 36 18 08 N | 087 41 53 W |
| Erin Cemetery | Cemetery | 180 | Houston | 36 19 18 N | 087 41 28 W |
| Erin City Hall | Building | 136 | Houston | 36 19 06 N | 087 41 35 W |
| Erin Elementary School | School | 127 | Houston | 36 18 53 N | 087 40 28 W |
| Erin Hollow | Valley | | Stewart | 36 29 02 N | 087 51 03 W |
| Erin Post Office | Post Office | 135 | Houston | 36 19 04 N | 087 41 44 W |
| Erlanger Hospital | Hospital | 216 | Hamilton | 35 02 56 N | 085 17 28 W |
| Ernest Fox Island (historical) | Island | 305 | Jefferson | 35 56 48 N | 083 29 27 W |
| Ernest L Ross Elementary School | School | 236 | Bradley | 35 12 23 N | 084 51 26 W |
| Ernest Taylor Dam | Dam | 600 | Sequatchie | 35 15 12 N | 085 23 18 W |
| Ernest Taylor Lake | Reservoir | 600 | Sequatchie | 35 15 12 N | 085 23 18 W |
| Ernest Vickers Dam | Dam | 128 | Carroll | 35 59 48 N | 088 28 00 W |
| Ernest Vickers Lake | Reservoir | 127 | Carroll | 35 59 48 N | 088 28 00 W |
| Ernestville | Populated Place | 564 | Unicoi | 36 04 17 N | 082 30 10 W |
| Ernie King Hollow | Valley | | Polk | 35 12 11 N | 084 30 25 W |
| Erranton Cemetery | Cemetery | 210 | Dickson | 36 00 08 N | 087 31 11 W |
| Ervin Branch | Stream | | Hardeman | 35 13 42 N | 088 49 26 W |
| Ervin Cemetery | Cemetery | 239 | Moore | 35 09 29 N | 086 21 18 W |
| Ervin Chapel | Church | 372 | Hamblen | 36 16 06 N | 083 08 11 W |
| Ervine Cemetery | Cemetery | 202 | Maury | 35 33 52 N | 087 00 11 W |
| Erwin | Populated Place | 510 | Unicoi | 36 08 42 N | 082 25 00 W |
| Erwin Cemetery | Cemetery | 268 | Bedford | 35 30 42 N | 086 18 19 W |
| Erwin Cemetery | Cemetery | 235 | Marshall | 35 27 33 N | 086 41 52 W |
| Erwin Cemetery | Cemetery | 190 | Maury | 35 43 32 N | 087 10 12 W |
| Erwin Cemetery | Cemetery | 260 | Meigs | 35 19 18 N | 084 45 12 W |
| Erwin Cemetery | Cemetery | 220 | Meigs | 35 22 07 N | 084 51 45 W |
| Erwin City Hall | Building | 511 | Unicoi | 36 08 41 N | 082 24 57 W |
| Erwin Post Office | Post Office | 511 | Unicoi | 36 08 46 N | 082 24 57 W |
| Erwin Presbyterian Church | Church | 513 | Unicoi | 36 08 40 N | 082 24 54 W |
| Erwin Slave Cemetery | Cemetery | 238 | Rutherford | 35 34 29 N | 086 25 58 W |
| Eskind Biomedical Library | Building | 172 | Davidson | 36 08 35 N | 086 48 09 W |
| Eskridge Cemetery | Cemetery | 277 | Franklin | 35 05 53 N | 086 15 59 W |
| Eskridge Cemetery (historical) | Cemetery | 149 | Davidson | 36 04 35 N | 086 33 40 W |
| Eskridge Cemetery (historical) | Cemetery | 149 | Rutherford | 36 03 54 N | 086 32 03 W |
| Eslick Branch | Stream | | Lincoln | 35 08 54 N | 086 23 05 W |
| Espey Cemetery | Cemetery | 158 | Rutherford | 35 59 46 N | 086 28 51 W |
| Espy Cemetery | Cemetery | 381 | Cannon | 35 41 22 N | 086 06 60 W |
| Esquire Estates | Populated Place | 168 | Rutherford | 35 54 26 N | 086 22 10 W |
| Essary Springs | Populated Place | 129 | Hardeman | 35 00 43 N | 088 47 53 W |
| Essary Springs Baptist Church | Church | 116 | Hardeman | 35 00 38 N | 088 47 45 W |
| Essary Springs Cemetery | Cemetery | 148 | Hardeman | 35 00 43 N | 088 48 13 W |
| Esslinger Cemetery | Cemetery | 388 | Sevier | 35 58 32 N | 083 33 19 W |
| Estabrook Hall | Building | 261 | Knox | 35 57 20 N | 083 55 26 W |
| Estanaula (historical) | Populated Place | 98 | Haywood | 35 27 35 N | 089 05 30 W |
| Estanelle School | School | 274 | Monroe | 35 23 03 N | 084 22 60 W |
| Estep Branch | Stream | | Carter | 36 26 20 N | 082 02 48 W |
| Estep Cemetery | Cemetery | 647 | Carter | 36 18 13 N | 082 07 16 W |
| Estep Cemetery | Cemetery | 577 | Carter | 36 22 51 N | 082 12 36 W |
| Estep Hollow | Valley | | Carter | 36 26 23 N | 082 02 39 W |
| Estep Hollow | Valley | | Claiborne | 36 35 12 N | 083 29 56 W |
| Estep Physical Fitness Center | Building | 161 | Montgomery | 36 37 41 N | 087 27 02 W |
| Estes Acres | Populated Place | 169 | Rutherford | 35 57 47 N | 086 22 18 W |
| Estes Branch | Stream | | Lewis | 35 32 15 N | 087 21 16 W |