Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Seals Cemetery | Cemetery | 238 | Robertson | 36 31 37 N | 086 42 50 W |
| Searcy Cemetery | Cemetery | 170 | Rutherford | 35 55 52 N | 086 30 60 W |
| Searcy Cemetery | Cemetery | 154 | Rutherford | 35 57 53 N | 086 24 34 W |
| Searcys Ferry (historical) | Crossing | 109 | Montgomery | 36 29 19 N | 087 22 59 W |
| Seaton | Populated Place | 292 | Blount | 35 43 55 N | 083 52 15 W |
| Seaton Branch | Stream | | Sevier | 35 48 22 N | 083 32 18 W |
| Seaton Cemetery | Cemetery | 445 | Washington | 36 08 54 N | 082 34 17 W |
| Seaton Hollow | Valley | | Wayne | 35 07 50 N | 087 54 21 W |
| Seaton Spring | Populated Place | 377 | Sevier | 35 48 41 N | 083 29 45 W |
| Seaton Spring | Spring | 469 | Greene | 36 08 10 N | 082 38 35 W |
| Seaton Spring | Spring | 469 | Washington | 36 08 37 N | 082 34 29 W |
| Seaton Subdivision | Populated Place | 537 | Washington | 36 19 34 N | 082 22 54 W |
| Seaton Top | Summit | 614 | Sevier | 35 48 23 N | 083 29 26 W |
| Seats Chapel | Church | 191 | Henderson | 35 48 42 N | 088 29 48 W |
| Seats Landing | Locale | 122 | Davidson | 36 10 05 N | 086 56 27 W |
| Seavy-Lull Mine | Mine | 263 | Lawrence | 35 01 51 N | 087 36 12 W |
| Seay Hill | Summit | 295 | Wilson | 36 12 17 N | 086 22 27 W |
| Seay Hollow | Valley | | Hawkins | 36 17 07 N | 083 00 11 W |
| Seay Hubbard United Methodist Church | Church | 138 | Davidson | 36 08 48 N | 086 45 48 W |
| Seay School | School | 164 | Wilson | 36 12 42 N | 086 19 40 W |
| Seay Spring | Spring | 126 | Stewart | 36 30 46 N | 087 41 47 W |
| Seays Church (historical) | Church | 166 | Wilson | 36 12 26 N | 086 19 45 W |
| Sebands Branch | Stream | | Scott | 36 23 32 N | 084 40 07 W |
| Sebastian Pond | Lake | 279 | Moore | 35 17 55 N | 086 22 53 W |
| Sebbles Mill (historical) | Locale | 125 | Stewart | 36 20 45 N | 087 52 49 W |
| Sebert Prospect | Mine | 682 | Johnson | 36 36 29 N | 081 48 02 W |
| Sebowisha | Populated Place | 152 | Smith | 36 08 17 N | 085 52 08 W |
| Sebowisha Post Office (historical) | Post Office | 152 | Smith | 36 08 17 N | 085 52 08 W |
| Sebring Cemetery (historical) | Cemetery | 149 | Davidson | 36 07 27 N | 086 35 36 W |
| Second Avenue Church of Christ | Church | 229 | Marshall | 35 27 33 N | 086 47 17 W |
| Second Baptist Church | Church | 264 | Anderson | 36 06 45 N | 084 07 27 W |
| Second Baptist Church | Church | 205 | Hamilton | 35 01 38 N | 085 16 59 W |
| Second Baptist Church | Church | 134 | Hardin | 35 13 32 N | 088 13 51 W |
| Second Baptist Church | Church | 290 | Knox | 35 59 54 N | 083 55 33 W |
| Second Baptist Church | Church | 269 | Loudon | 35 47 26 N | 084 16 20 W |
| Second Baptist Church | Church | 89 | Shelby | 35 06 54 N | 090 03 43 W |
| Second Baptist Church | Church | 93 | Shelby | 35 07 55 N | 089 54 23 W |
| Second Baptist Church | Church | 174 | Wilson | 36 11 50 N | 086 17 59 W |
| Second Bethlehem Church | Church | 396 | Scott | 36 32 57 N | 084 26 54 W |
| Second Bethlehem Church | Church | 394 | Scott | 36 33 00 N | 084 26 56 W |
| Second Branch | Stream | | Marion | 35 15 34 N | 085 30 02 W |
| Second Branch | Stream | | Sevier | 35 38 00 N | 083 32 40 W |
| Second Church of Christ Science | Church | 94 | Shelby | 35 07 22 N | 089 56 40 W |
| Second Congregational Church | Church | 93 | Shelby | 35 07 11 N | 090 02 11 W |
| Second Creek | Stream | | Cumberland | 35 51 30 N | 085 09 29 W |
| Second Creek | Stream | | DeKalb | 36 03 19 N | 085 45 28 W |
| Second Creek | Stream | | Knox | 35 57 20 N | 083 55 17 W |
| Second Creek | Stream | | Trousdale | 36 22 31 N | 086 12 37 W |
| Second Creek Baptist Church | Church | 249 | Lawrence | 35 01 26 N | 087 20 15 W |
| Second Creek Cemetery | Cemetery | 252 | Lawrence | 35 01 24 N | 087 20 12 W |
| Second Creek Church | Church | 162 | Hardin | 35 00 56 N | 087 59 07 W |
| Second Creek Island | Island | 137 | Trousdale | 36 22 24 N | 086 12 41 W |
| Second Creek Methodist Church (historical) | Church | 200 | DeKalb | 36 03 12 N | 085 45 29 W |
| Second Creek School (historical) | School | 201 | DeKalb | 36 03 17 N | 085 45 17 W |
| Second Creek School (historical) | School | 249 | Lawrence | 35 01 26 N | 087 20 08 W |
| Second Grove Church | Church | 242 | Robertson | 36 30 07 N | 086 41 18 W |
| Second Knob | Summit | 247 | Maury | 35 37 19 N | 087 02 59 W |
| Second Laurel Branch | Stream | | Scott | 36 14 26 N | 084 28 31 W |
| Second Missionary Baptist Church | Church | 171 | Davidson | 36 07 21 N | 086 47 12 W |
| Second Presbyterian Church | Church | 296 | Blount | 35 44 55 N | 083 59 05 W |
| Second Presbyterian Church | Church | 178 | Davidson | 36 06 38 N | 086 48 03 W |
| Second Presbyterian Church | Church | 277 | Knox | 35 57 08 N | 083 56 45 W |
| Second Presbyterian Church | Church | 93 | Shelby | 35 07 24 N | 089 55 37 W |
| Second Prong | Stream | | Unicoi | 36 06 06 N | 082 29 10 W |
| Second Street Church of Christ | Church | 213 | Giles | 35 12 06 N | 087 01 52 W |
| Second Tunnel | Tunnel | 604 | Carter | 36 15 56 N | 082 10 16 W |
| Second United Methodist Church | Church | 282 | Knox | 35 57 56 N | 083 56 05 W |
| Second United Presbyterian Church | Church | 205 | Hamilton | 35 02 53 N | 085 18 45 W |
| Secondary Retention Reservoir | Reservoir | 335 | Coffee | 35 22 24 N | 086 03 12 W |
| Secondary Retention Reservoir Dam | Dam | 335 | Coffee | 35 22 24 N | 086 03 12 W |
| Secrest Cemetery | Cemetery | 237 | Maury | 35 39 47 N | 086 57 08 W |
| Secret Prayer Hollow | Valley | | Houston | 36 18 03 N | 087 40 28 W |
| Sectionhouse Hollow | Valley | | Humphreys | 36 05 06 N | 087 50 33 W |
| Sedberry Cemetery | Cemetery | 292 | Williamson | 35 48 12 N | 087 00 35 W |
| Sedberry Cemetery | Cemetery | 308 | Williamson | 35 48 43 N | 087 01 56 W |
| Seeber Cemetery | Cemetery | 502 | Anderson | 36 10 11 N | 084 12 54 W |
| Seeber Creek | Stream | | Anderson | 36 05 19 N | 084 16 46 W |
| Seeber Creek | Stream | | Anderson | 36 07 03 N | 084 14 03 W |
| Seeber Flats | Populated Place | 501 | Anderson | 36 10 07 N | 084 12 57 W |
| Seed Tick Branch | Stream | | Hamilton | 35 13 25 N | 085 18 51 W |
| Seedtick Creek | Stream | | Humphreys | 35 50 10 N | 087 49 02 W |
| Seehorn Creek | Stream | | Jefferson | 36 02 15 N | 083 20 13 W |
| Seiber Cemetery | Cemetery | 257 | Anderson | 36 03 42 N | 084 18 03 W |
| Seiber Chapel (historical) | Church | 249 | Lewis | 35 27 46 N | 087 38 39 W |
| Seifarth Cemetery | Cemetery | 200 | Humphreys | 36 06 33 N | 087 42 30 W |
| Seivers Cemetery | Cemetery | 288 | Anderson | 36 09 28 N | 084 10 34 W |
| Selaris Lake | Lake | 119 | Haywood | 35 34 08 N | 089 17 50 W |
| Selby (historical) | Populated Place | 352 | Putnam | 36 13 45 N | 085 28 36 W |
| Selby Cemetery | Cemetery | 407 | Cumberland | 35 46 58 N | 084 59 52 W |
| Selby Cemetery | Cemetery | 404 | Cumberland | 35 47 05 N | 085 00 03 W |
| Selby Cemetery | Cemetery | 493 | Cumberland | 35 48 59 N | 084 57 23 W |
| Selby Creek | Stream | | Cumberland | 35 47 30 N | 085 00 32 W |
| Self Cemetery | Cemetery | 110 | Dyer | 36 04 07 N | 089 15 54 W |
| Self Cemetery | Cemetery | 353 | Hawkins | 36 19 56 N | 083 00 18 W |
| Self Hollow | Valley | | Blount | 35 49 57 N | 083 56 01 W |
| Self Hollow | Valley | | Decatur | 35 25 15 N | 088 01 40 W |
| Self Landing | Locale | 110 | Decatur | 35 25 19 N | 088 01 18 W |
| Self Slough | Stream | | Decatur | 35 25 30 N | 088 01 49 W |
| Selkirk (historical) | Populated Place | 236 | Roane | 35 54 10 N | 084 21 15 W |
| Sellers Bluff | Cliff | 190 | Maury | 35 40 29 N | 087 05 53 W |
| Sellers Branch | Stream | | Monroe | 35 30 38 N | 084 02 36 W |
| Sellers Cemetery | Cemetery | 179 | Carroll | 35 53 32 N | 088 23 49 W |
| Sellers Hollow | Valley | | Maury | 35 45 26 N | 087 03 09 W |
| Sellers Mine | Mine | 202 | Maury | 35 40 42 N | 087 04 57 W |
| Sells Cemetery | Cemetery | 503 | Fentress | 36 18 58 N | 085 07 18 W |
| Sells Cemetery | Cemetery | 305 | Overton | 36 29 38 N | 085 16 30 W |
| Sells Mill Creek | Stream | | Overton | 36 28 09 N | 085 08 15 W |
| Selmer | Populated Place | 137 | McNairy | 35 10 12 N | 088 35 32 W |
| Selmer Church | Church | 154 | McNairy | 35 09 44 N | 088 35 31 W |
| Selmer Elementary School | School | 134 | McNairy | 35 09 53 N | 088 35 39 W |