Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Selmer Middle School | School | 160 | McNairy | 35 10 27 N | 088 35 33 W |
| Selph School (historical) | School | 317 | Lawrence | 35 22 52 N | 087 13 50 W |
| Seminary Cemetery | Cemetery | 169 | Rutherford | 35 53 14 N | 086 26 09 W |
| Seminary Cemetery | Cemetery | 156 | Weakley | 36 07 53 N | 088 39 39 W |
| Seminary Church | Church | 158 | Weakley | 36 07 54 N | 088 39 42 W |
| Seminary Hill School (historical) | School | 331 | Coffee | 35 25 05 N | 086 06 03 W |
| Seminary School | School | 174 | Rutherford | 35 55 41 N | 086 32 57 W |
| Seminary School (historical) | School | 509 | Washington | 36 13 59 N | 082 26 53 W |
| Seminole Subdivision | Populated Place | 574 | Cumberland | 35 51 22 N | 085 04 40 W |
| Seminole Woods (subdivision) | Populated Place | 522 | Washington | 36 17 34 N | 082 22 60 W |
| Seneker Cemetery | Cemetery | 569 | Sullivan | 36 34 34 N | 082 18 44 W |
| Seneker Cemetery | Cemetery | 552 | Sullivan | 36 35 18 N | 082 18 23 W |
| Seng Branch | Stream | | Sevier | 35 43 17 N | 083 33 05 W |
| Seng Cove | Valley | | Johnson | 36 35 31 N | 081 43 33 W |
| Seng Cove Branch | Stream | | Johnson | 36 35 30 N | 081 43 36 W |
| Seng Patch Branch | Stream | | Sevier | 35 35 03 N | 083 37 46 W |
| Sengtown | Populated Place | 261 | Sumner | 36 36 48 N | 086 26 15 W |
| Sensabaugh Branch | Stream | | Hawkins | 36 25 11 N | 082 56 04 W |
| Sensabaugh Branch | Stream | | Hawkins | 36 34 46 N | 082 36 59 W |
| Sensabaugh Cemetery | Cemetery | 384 | Hawkins | 36 34 54 N | 082 37 42 W |
| Sensabaugh Ridge | Ridge | 434 | Hawkins | 36 34 33 N | 082 37 60 W |
| Sensabaugh Tunnel | Tunnel | 395 | Hawkins | 36 34 36 N | 082 37 29 W |
| Sensaboy Spring | Spring | 227 | Meigs | 35 41 32 N | 084 41 39 W |
| Sensing Cemetery | Cemetery | 153 | Dickson | 36 15 06 N | 087 16 12 W |
| Senter Hill Church | Church | 285 | Warren | 35 33 41 N | 085 38 49 W |
| Sentertown | Populated Place | 310 | Knox | 36 03 02 N | 083 49 48 W |
| Sentertown Missionary Baptist Church | Church | 312 | Knox | 36 03 06 N | 083 49 44 W |
| Sentinel Heights | Populated Place | 279 | Rhea | 35 30 09 N | 084 59 56 W |
| Separate Pond (historical) | Lake | 77 | Lauderdale | 35 49 16 N | 089 36 34 W |
| Sequatchie | Populated Place | 200 | Marion | 35 06 56 N | 085 35 37 W |
| Sequatchie Chapel | Church | 624 | Sequatchie | 35 12 25 N | 085 22 26 W |
| Sequatchie College | Locale | 251 | Bledsoe | 35 30 39 N | 085 17 08 W |
| Sequatchie County | Civil | 217 | Sequatchie | 35 20 00 N | 085 23 00 W |
| Sequatchie County Courthouse | Building | 216 | Sequatchie | 35 22 17 N | 085 23 15 W |
| Sequatchie County High School | School | 232 | Sequatchie | 35 22 48 N | 085 23 13 W |
| Sequatchie County Junior High School | School | 226 | Sequatchie | 35 22 44 N | 085 23 19 W |
| Sequatchie County Middle School | School | 226 | Sequatchie | 35 22 42 N | 085 23 20 W |
| Sequatchie First Baptist Church | Church | 206 | Marion | 35 06 44 N | 085 35 53 W |
| Sequatchie Post Office | Post Office | 201 | Marion | 35 07 00 N | 085 35 38 W |
| Sequatchie River | Stream | | Marion | 35 01 31 N | 085 38 08 W |
| Sequatchie School (historical) | School | 202 | Marion | 35 06 42 N | 085 35 48 W |
| Sequatchie Valley | Valley | | Marion | 35 01 10 N | 085 37 05 W |
| Sequatchie Valley Golf and Country Club | Locale | 185 | Marion | 35 03 09 N | 085 43 27 W |
| Sequatchie Valley Memorial Gardens | Cemetery | 205 | Marion | 35 03 43 N | 085 38 33 W |
| Sequatchie-Bledsoe Vocational Center | School | 231 | Sequatchie | 35 22 44 N | 085 23 10 W |
| Sequatchie-Bledsoe Vocational Training Center | School | 239 | Bledsoe | 35 29 56 N | 085 17 54 W |
| Sequoia Grove | Populated Place | 251 | Bradley | 35 12 45 N | 084 50 52 W |
| Sequoia Hills | Populated Place | 422 | Greene | 36 05 50 N | 082 52 24 W |
| Sequooyah Estates | Populated Place | 429 | Hamblen | 36 09 49 N | 083 16 40 W |
| Sequoyah Birthplace Memorial | Park | 263 | Monroe | 35 34 48 N | 084 13 02 W |
| Sequoyah Branch Johnson Mental Health Center | Hospital | 232 | Hamilton | 35 14 45 N | 085 11 20 W |
| Sequoyah Church | Church | 229 | Hamilton | 35 13 09 N | 085 09 28 W |
| Sequoyah Church | Church | 248 | Hamilton | 35 15 06 N | 085 06 57 W |
| Sequoyah Council Boy Scout Reservation | Locale | 340 | Hamblen | 36 19 44 N | 083 10 06 W |
| Sequoyah Dock | Locale | 333 | Anderson | 36 14 53 N | 084 03 15 W |
| Sequoyah Elementary School | School | 274 | Knox | 35 56 08 N | 083 58 03 W |
| Sequoyah Estates | Populated Place | 311 | Monroe | 35 30 32 N | 084 22 50 W |
| Sequoyah Heights | Populated Place | 274 | Blount | 35 46 12 N | 084 10 04 W |
| Sequoyah Heights (subdivision) | Populated Place | 529 | Washington | 36 21 56 N | 082 24 13 W |
| Sequoyah Hills | Populated Place | 225 | Hamilton | 35 11 53 N | 085 09 15 W |
| Sequoyah Hills | Populated Place | 255 | Knox | 35 56 10 N | 083 58 29 W |
| Sequoyah Hills Presbyterian Church | Church | 262 | Knox | 35 56 02 N | 083 57 53 W |
| Sequoyah Landing | Locale | 311 | Anderson | 36 15 28 N | 084 03 13 W |
| Sequoyah Landing Cabin Area | Locale | 311 | Anderson | 36 15 32 N | 084 03 14 W |
| Sequoyah Marina | Locale | 311 | Anderson | 36 15 34 N | 084 03 13 W |
| Sequoyah Nuclear Plant | Locale | 35 | Hamilton | 35 13 36 N | 085 05 31 W |
| Sequoyah Park | Park | 251 | Knox | 35 55 39 N | 083 58 12 W |
| Sequoyah School | School | 299 | Monroe | 35 35 59 N | 084 22 01 W |
| Sequoyah Shores | Populated Place | 248 | Roane | 35 50 50 N | 084 31 44 W |
| Sequoyah Vocational Technical School | School | 259 | Hamilton | 35 13 44 N | 085 10 02 W |
| Serena Chapel | Church | 224 | Hamilton | 35 09 45 N | 085 11 31 W |
| Sergeant Alvin York Mill State Historic Area | Park | 269 | Fentress | 36 32 32 N | 084 57 60 W |
| Serles | Populated Place | 113 | Hardeman | 35 10 09 N | 088 50 37 W |
| Service Branch | Stream | | Hamilton | 35 10 59 N | 085 20 13 W |
| Service Branch | Stream | | Monroe | 35 16 17 N | 084 09 12 W |
| Service Branch | Stream | | Overton | 36 10 56 N | 085 10 04 W |
| Service Flat | Flat | 687 | Scott | 36 14 06 N | 084 34 02 W |
| Service Tree Branch | Stream | | Monroe | 35 19 33 N | 084 04 59 W |
| Servilla | Populated Place | 289 | Polk | 35 14 07 N | 084 27 42 W |
| Sesquicentennial Park | Park | 131 | Carroll | 36 00 29 N | 088 23 01 W |
| Sesson Hollow | Valley | | Humphreys | 36 12 24 N | 087 53 51 W |
| Seth | Populated Place | 273 | Maury | 35 32 52 N | 087 17 23 W |
| Seth Hollow | Valley | | Jackson | 36 20 04 N | 085 33 24 W |
| Seton Hollow | Valley | | Lewis | 35 31 15 N | 087 17 55 W |
| Setters Lake | Reservoir | 170 | Davidson | 36 16 24 N | 086 54 37 W |
| Setters School (historical) | School | 167 | Davidson | 36 16 21 N | 086 55 25 W |
| Settle Cemetery | Cemetery | 159 | Stewart | 36 23 41 N | 087 52 13 W |
| Settle Cemetery | Cemetery | 129 | Stewart | 36 27 08 N | 087 50 57 W |
| Settle Hollow | Valley | | Stewart | 36 23 42 N | 087 52 20 W |
| Settle Point School (historical) | School | 160 | Hickman | 35 46 00 N | 087 34 06 W |
| Settlers Knob (subdivision) | Populated Place | 172 | Wilson | 36 11 46 N | 086 31 39 W |
| Settlers Point | Populated Place | 207 | Williamson | 35 56 57 N | 086 56 48 W |
| Seuler Cemetery | Cemetery | 233 | Roane | 35 52 48 N | 084 31 40 W |
| Seven (historical) | Populated Place | 248 | Lawrence | 35 16 18 N | 087 14 20 W |
| Seven Cedars | Populated Place | 282 | McMinn | 35 20 42 N | 084 31 60 W |
| Seven Island Shoals | Bar | 254 | Knox | 35 57 15 N | 083 42 06 W |
| Seven Islands | Island | 257 | Knox | 35 57 05 N | 083 42 04 W |
| Seven Islands | Island | 226 | Roane | 35 47 38 N | 084 28 25 W |
| Seven Islands | Populated Place | 284 | Knox | 35 56 53 N | 083 42 14 W |
| Seven Islands Church | Church | 284 | Knox | 35 56 56 N | 083 42 16 W |
| Seven Islands Church | Church | 275 | Knox | 35 57 01 N | 083 42 21 W |
| Seven Islands Shoals | Bar | 226 | Roane | 35 47 40 N | 084 28 55 W |
| Seven Knobs | Summit | 284 | Jackson | 36 17 07 N | 085 35 27 W |
| Seven Mile Eddy | Rapids | 256 | Sevier | 35 56 43 N | 083 41 10 W |
| Seven Mile Ferry (historical) | Crossing | 109 | Montgomery | 36 29 33 N | 087 20 19 W |
| Seven Mile Island | Island | 110 | Montgomery | 36 29 16 N | 087 20 45 W |
| Seven Oaks | Populated Place | 364 | Hamblen | 36 11 40 N | 083 23 55 W |
| Seven Oaks (subdivision) | Populated Place | 422 | Hawkins | 36 33 30 N | 082 38 60 W |
| Seven Oaks Park | Park | 173 | Davidson | 36 06 29 N | 086 41 56 W |
| Seven Points | Locale | 153 | Davidson | 36 07 55 N | 086 34 10 W |