Feature Name | Class | Elev. meters | County | Latitude DMS | Longitude DMS |
| Southern Lutheran Orphanage | Locale | 354 | Salem (city) | 37 17 25 N | 080 02 30 W |
| Southern Magisterial District | Civil | 863 | Tazewell | 37 03 55 N | 081 31 10 W |
| Southern Pines | Populated Place | 46 | Dinwiddie | 37 12 57 N | 077 28 19 W |
| Southern Pines | Populated Place | 394 | Roanoke | 37 12 37 N | 079 59 00 W |
| Southern Points | Populated Place | 0 | Virginia Beach (city) | 36 51 44 N | 076 03 19 W |
| Southern Seminary Junior College | School | 283 | Buena Vista (city) | 37 44 24 N | 079 21 00 W |
| Southern Service Corporation Dam | Dam | 93 | Powhatan | 37 32 37 N | 077 52 11 W |
| Southern Shopping Center | Locale | 4 | Norfolk (city) | 36 54 54 N | 076 15 19 W |
| Southern Virginia Mental Health Institute | Hospital | 133 | Danville (city) | 36 33 17 N | 079 24 36 W |
| Southern Yards | Locale | 498 | Wise | 36 53 59 N | 082 47 32 W |
| Southern-Shreve Family Graveyard | Cemetery | 92 | Arlington | 38 52 49 N | 077 07 40 W |
| Southgate (subdivision) | Populated Place | 635 | Montgomery | 37 13 06 N | 080 24 49 W |
| Southgate Plaza Shopping Center | Locale | 2 | Chesapeake (city) | 36 48 06 N | 076 16 29 W |
| Southgate Shopping Center | Locale | 123 | Culpeper | 38 27 45 N | 078 00 09 W |
| Southhampton Hills (subdivision) | Populated Place | 67 | Richmond | 37 32 28 N | 077 31 54 W |
| Southhampton Speedway | Locale | 28 | Southampton | 36 36 60 N | 077 17 31 W |
| Southland Acres | Populated Place | 273 | Lynchburg (city) | 37 21 15 N | 079 11 18 W |
| Southlawn Memorial Park | Cemetery | 46 | Prince George | 37 09 49 N | 077 21 56 W |
| Southpark Shopping Center | Locale | 233 | Winchester (city) | 39 09 23 N | 078 11 09 W |
| Southport Industrial Park | Locale | 109 | Chesterfield | 37 30 13 N | 077 35 59 W |
| Southridge | Populated Place | 96 | Fairfax | 38 55 07 N | 077 10 60 W |
| Southside Academy | School | 5 | Chesapeake (city) | 36 49 03 N | 076 13 42 W |
| Southside Baptist Church | Church | 52 | Petersburg (city) | 37 12 02 N | 077 25 42 W |
| Southside Baptist Temple | Church | 64 | Richmond | 37 29 07 N | 077 29 31 W |
| Southside Church | Church | 61 | Chesterfield | 37 26 06 N | 077 29 28 W |
| Southside Church | Church | 19 | Suffolk (city) | 36 41 36 N | 076 36 23 W |
| Southside Church of Christ | Church | 227 | Winchester (city) | 39 08 32 N | 078 10 23 W |
| Southside Community College | School | 110 | Brunswick | 36 50 20 N | 077 55 04 W |
| Southside Community Health Center | Hospital | 157 | Albemarle | 37 49 07 N | 078 35 39 W |
| Southside Community Hospital | Hospital | 105 | Prince Edward | 37 18 11 N | 078 24 16 W |
| Southside Community Interdenominational Church | Church | 141 | Mecklenburg | 36 43 39 N | 078 07 38 W |
| Southside Convalescent Home | Building | 139 | Nottoway | 37 04 34 N | 078 00 24 W |
| Southside Elementary School | School | 69 | Dinwiddie | 37 07 48 N | 077 32 07 W |
| Southside High School | School | 74 | Dinwiddie | 37 06 13 N | 077 33 47 W |
| Southside High School | School | 222 | Pittsylvania | 36 41 20 N | 079 22 16 W |
| Southside Hills | Populated Place | 366 | Salem (city) | 37 16 30 N | 080 04 44 W |
| Southside Industrial Park | Locale | 315 | Salem (city) | 37 17 02 N | 080 04 49 W |
| Southside Magisterial District | Civil | 244 | Appomattox | 37 18 14 N | 078 51 19 W |
| Southside Meadows | Populated Place | 18 | Suffolk (city) | 36 42 01 N | 076 35 55 W |
| Southside Park | Park | 100 | Fairfax | 38 53 06 N | 077 15 12 W |
| Southside Plaza Shopping Center | Locale | 61 | Chesterfield | 37 30 11 N | 077 28 41 W |
| Southside Regional Medical Center | Hospital | 39 | Petersburg (city) | 37 13 03 N | 077 23 51 W |
| Southside Ridge | Ridge | 429 | Botetourt | 37 31 00 N | 079 36 37 W |
| Southside School | School | 98 | Mecklenburg | 36 35 11 N | 078 13 03 W |
| Southside School (historical) | School | 180 | Pittsylvania | 36 32 46 N | 079 23 13 W |
| Southside Shores | Populated Place | 76 | Brunswick | 36 33 05 N | 077 51 15 W |
| Southside Speedway | Locale | 92 | Chesterfield | 37 27 03 N | 077 37 43 W |
| Southside Square Shopping Center | Locale | 37 | Emporia (city) | 36 41 54 N | 077 32 31 W |
| Southside Station Richmond Post Office | Post Office | 27 | Richmond | 37 29 48 N | 077 26 37 W |
| Southside Virginia Community College | School | 47 | Greensville | 36 42 26 N | 077 33 59 W |
| Southside Vocational School | School | 144 | Nottoway | 37 09 57 N | 078 06 57 W |
| Southside Volunteer Rescue Squad | Building | | Mecklenburg | 37 13 25 N | 078 14 35 W |
| Southside Wastewater Treatment Plant | Locale | 126 | Pittsylvania | 36 33 35 N | 079 22 09 W |
| Southview | Populated Place | 220 | Frederick | 39 07 50 N | 078 09 19 W |
| Southview Methodist Church | Church | 225 | Lynchburg (city) | 37 23 53 N | 079 09 24 W |
| Southview School | School | 358 | Roanoke | 37 19 26 N | 079 59 43 W |
| Southwest Branch Back River | Stream | | Hampton (city) | 37 06 01 N | 076 19 52 W |
| Southwest Cove | Bay | -3 | Westmoreland | 38 06 08 N | 076 42 59 W |
| Southwest Gut | Gut | 1 | Accomack | 37 39 03 N | 075 36 43 W |
| Southwest Historic District | Park | 305 | Roanoke (city) | 37 16 57 N | 079 58 29 W |
| Southwest Mountains | Ridge | 364 | Albemarle | 38 05 44 N | 078 20 06 W |
| Southwest Plaza Shopping Center | Locale | 355 | Roanoke (city) | 37 14 48 N | 080 01 50 W |
| Southwest Swamp | Stream | | Sussex | 36 56 39 N | 077 23 02 W |
| Southwest Virginia 4-H Center | Locale | 639 | Washington | 36 43 45 N | 081 55 19 W |
| Southwest Virginia Community College | School | 724 | Tazewell | 37 00 20 N | 081 47 42 W |
| Southwest Virginia Memorial Bridge | Bridge | 518 | Pulaski | 37 08 20 N | 080 34 29 W |
| Southwestern High School | School | 24 | Suffolk (city) | 36 38 16 N | 076 48 12 W |
| Southwestern School | School | 4 | Chesapeake (city) | 36 47 30 N | 076 24 21 W |
| Southwestern Virginia Mental Health Institute | Hospital | 682 | Smyth | 36 49 58 N | 081 30 40 W |
| Southwick Park | Park | 132 | Danville (city) | 36 33 32 N | 079 24 03 W |
| Southwood | Populated Place | 20 | Fairfax | 38 42 48 N | 077 06 20 W |
| Southwood Estates Mobile Home Park | Populated Place | 139 | Albemarle | 37 59 52 N | 078 31 26 W |
| Southwood Hills | Populated Place | 291 | Frederick | 39 18 15 N | 078 19 14 W |
| Southwoods | Populated Place | 337 | Roanoke | 37 14 40 N | 080 00 37 W |
| Southwyck Plaza Shopping Center | Locale | 159 | Pittsylvania | 36 33 07 N | 079 24 03 W |
| Sowders Chapel | Church | 433 | Montgomery | 37 06 48 N | 080 15 44 W |
| Sowego | Populated Place | 72 | Fauquier | 38 35 56 N | 077 34 35 W |
| Sowell Branch | Stream | | Albemarle | 37 55 52 N | 078 33 07 W |
| Sowers | Populated Place | 643 | Floyd | 37 00 12 N | 080 22 45 W |
| Sowers Cemetery | Cemetery | 764 | Floyd | 36 56 46 N | 080 24 27 W |
| Soyar Cemetery | Cemetery | 228 | Pittsylvania | 36 36 29 N | 079 33 45 W |
| Soyar Mountain | Summit | 261 | Pittsylvania | 36 35 34 N | 079 33 39 W |
| Spady Creek | Stream | | Northampton | 37 18 26 N | 075 55 03 W |
| Spain Cove | Bay | 0 | Accomack | 37 56 49 N | 076 02 22 W |
| Spainville | Populated Place | 120 | Nottoway | 37 11 20 N | 077 54 58 W |
| Spangler | Populated Place | 348 | Salem (city) | 37 17 57 N | 080 04 37 W |
| Spangler Cemetery | Cemetery | 505 | Lee | 36 41 13 N | 083 11 20 W |
| Spangler Dam | Dam | 80 | Greensville | 36 49 13 N | 077 38 29 W |
| Spangler Lake | Reservoir | 80 | Greensville | 36 49 13 N | 077 38 29 W |
| Spanglers Mill (historical) | Locale | 164 | Shenandoah | 38 59 21 N | 078 22 12 W |
| Spanish Grove | Populated Place | 177 | Mecklenburg | 36 47 45 N | 078 32 07 W |
| Spanish Grove Church | Church | 127 | Halifax | 36 44 01 N | 078 43 45 W |
| Sparkling Springs | Populated Place | 557 | Rockingham | 38 33 05 N | 078 57 06 W |
| Sparks Cemetery | Cemetery | 917 | Buchanan | 37 15 08 N | 081 45 56 W |
| Sparrow Point | Cape | 1 | Northampton | 37 25 04 N | 075 57 57 W |
| Sparrow Point | Cape | -3 | Northampton | 37 32 35 N | 075 56 18 W |
| Sparrow Road Elementary School | School | 5 | Chesapeake (city) | 36 48 42 N | 076 13 30 W |
| Sparta | Populated Place | 50 | Caroline | 37 59 30 N | 077 13 49 W |
| Sparta Volunteer Fire Department Company 4 | Building | | Caroline | 37 59 23 N | 077 14 30 W |
| Spartan Square Shopping Center | Locale | 318 | Salem (city) | 37 17 27 N | 080 04 54 W |
| Speaks Branch | Stream | | Lee | 36 37 09 N | 083 20 48 W |
| Speaks Chapel | Church | 427 | Lee | 36 38 13 N | 083 19 55 W |
| Spears Mountain | Summit | 495 | Buckingham | 37 33 43 N | 078 45 46 W |
| Spec | Populated Place | 338 | Botetourt | 37 27 16 N | 079 46 17 W |
| Spec Mines Branch | Stream | | Botetourt | 37 27 28 N | 079 46 05 W |
| Spec Mines Trail | Trail | 593 | Botetourt | 37 26 45 N | 079 44 40 W |
| Special Services Department Library | Building | 11 | Alexandria (city) | 38 49 25 N | 077 02 53 W |
| Speedwell | Populated Place | 707 | Wythe | 36 48 49 N | 081 10 18 W |
| Speedwell Elementary School | School | | Wythe | 37 22 04 N | 081 18 20 W |
| Speedwell Magisterial District | Civil | 779 | Wythe | 36 50 06 N | 081 08 24 W |